المؤلفون: Michaela Liedtke, Amarendra K. Neppalli, Elizabeth McGehee, Ehsan Malek, Saad Z. Usmani, Robert F. Cornell, Swapna Narayana, Ankit Kansagra, Natalie S. Callander, Elvira Umyarova, Parameswaran Hari, Arjun Lakshman, Ridhi Gupta, Barry Paul, Joshua Mansour, Zhubin Gahvari, Ujjawal H. Gandhi, William Varnado, Alyssa Barnstead, Saurabh Chhabra, Mark A. Fiala, Emma C. Scott, Megan Jagosky, Saranya Kodali, Ravi Vij, Yubin Kang, Kelly N. Godby, Luciano J. Costa, Shaji Kumar

المصدر: Leukemia. 33:2266-2275

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Oncology, Cancer Research, medicine.medical_specialty, Population, Antibodies, Monoclonal, Humanized, Article, Cohort Studies, Young Adult, 03 medical and health sciences, chemistry.chemical_compound, Antineoplastic Agents, Immunological, 0302 clinical medicine, Refractory, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, Immunologic Factors, Progression-free survival, education, Multiple myeloma, Aged, Aged, 80 and over, Isatuximab, education.field_of_study, Membrane Glycoproteins, business.industry, Antibodies, Monoclonal, Daratumumab, Hematology, Middle Aged, medicine.disease, ADP-ribosyl Cyclase 1, Carfilzomib, Progression-Free Survival, Regimen, 030104 developmental biology, chemistry, 030220 oncology & carcinogenesis, Female, Immunotherapy, Multiple Myeloma, business, Proteasome Inhibitors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::578f20b4b94ab5eea695d3fdb5fd3826Test
https://doi.org/10.1038/s41375-019-0435-7Test

المؤلفون: Jiri Mayer, Hans Carl Hasselbalch, Zdenek Racil, Lijuan Han, Angela Maurer, Anders Lindholm Sørensen, Deniz Gezer, Claudia Schubert, Julia Czech, Ivan G. Costa, Sabrina Cordua, Tim H. Brümmendorf, Barbora Weinbergerova, Nicolas Chatain, Morten Orebo Holmström, Lasse Kjær, Trine Alma Knudsen, Bernd Denecke, Thomas Stauffer Larsen, Vibe Skov, Julian Baumeister, Steffen Koschmieder, Kristina Feldberg, Blanka Kubešová, Tiago Maié, Gerhard Müller-Newen, Assja Crepcia

المصدر: Czech, J, Cordua, S, Weinbergerova, B, Baumeister, J, Crepcia, A, Han, L, Maié, T, Costa, I G, Denecke, B, Maurer, A, Schubert, C, Feldberg, K, Gezer, D, Brümmendorf, T H, Müller-Newen, G, Mayer, J, Racil, Z, Kubesova, B, Knudsen, T, Sørensen, A L, Holmström, M, Kjær, L, Skov, V, Larsen, T S, Hasselbalch, H C, Chatain, N & Koschmieder, S 2019, ' JAK2V617F but not CALR mutations confer increased molecular responses to interferon-α via JAK1/STAT1 activation ', Leukemia, vol. 33, no. 4, pp. 995-1010 . https://doi.org/10.1038/s41375-018-0295-6Test

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Cancer Research, CD34, Alpha interferon, Apoptosis, Antiviral Agents, Peripheral blood mononuclear cell, Mice, 03 medical and health sciences, 0302 clinical medicine, Downregulation and upregulation, Pegylated interferon, Biomarkers, Tumor, Tumor Cells, Cultured, medicine, Animals, Humans, Aged, Cell Proliferation, Retrospective Studies, Myeloproliferative Disorders, biology, business.industry, Interferon-alpha, Janus Kinase 1, Hematology, Janus Kinase 2, Middle Aged, Prognosis, Haematopoiesis, STAT1 Transcription Factor, 030104 developmental biology, Oncology, 030220 oncology & carcinogenesis, Mutation, biology.protein, Cancer research, Female, Stem cell, Calreticulin, business, Follow-Up Studies, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56f5523d5077aee3a85880cb282335b6Test
https://doi.org/10.1038/s41375-018-0295-6Test

المؤلفون: Alice S. Mims, Jessica Kohlschmidt, Sophia E. Maharry, Jonathan E. Kolitz, Christopher J. Walker, Shelley Orwick, Eunice S. Wang, Bayard L. Powell, James S. Blachly, Ann-Kathrin Eisfeld, Richard Stone, John C. Byrd, Deedra Nicolet, Albert de la Chapelle, Krzysztof Mrózek, Andrew J. Carroll, Clara D. Bloomfield

المصدر: Leukemia

مصطلحات موضوعية: Male, Adult, 0301 basic medicine, Oncology, congenital, hereditary, and neonatal diseases and abnormalities, Cancer Research, medicine.medical_specialty, Myeloid, Adolescent, Nonsense mutation, Article, Frameshift mutation, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Risk Factors, Internal medicine, medicine, Humans, Missense mutation, neoplasms, Aged, Aged, 80 and over, Neurofibromin 1, business.industry, Remission Induction, Myeloid leukemia, Adult Acute Myeloid Leukemia, Hematology, Middle Aged, Prognosis, medicine.disease, nervous system diseases, 3. Good health, Leukemia, Myeloid, Acute, Leukemia, 030104 developmental biology, medicine.anatomical_structure, Targeted Mutation, 030220 oncology & carcinogenesis, Mutation, Female, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01aeac8269a2e35669d6dc17adf5bbd7Test
https://doi.org/10.1038/s41375-018-0147-4Test

المؤلفون: Manja Meggendorfer, Niroshan Nadarajah, Annette Fasan, Claudia Haferlach, Sabine Jeromin, Alexander Höllein, Wolfgang Kern, Torsten Haferlach

المصدر: Leukemia. 32:2270-2274

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Oncology, Cancer Research, medicine.medical_specialty, Neoplasm, Residual, Myeloid, Adolescent, MEDLINE, Young Adult, 03 medical and health sciences, RUNX1 Translocation Partner 1 Protein, 0302 clinical medicine, Neoplasm Recurrence, Internal medicine, Runx1 runx1t1, medicine, Humans, Neoplasm, Young adult, Aged, Aged, 80 and over, business.industry, Hematology, Middle Aged, medicine.disease, Minimal residual disease, Leukemia, Myeloid, Acute, Leukemia, 030104 developmental biology, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Core Binding Factor Alpha 2 Subunit, Mutation, Female, Neoplasm Recurrence, Local, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f9ff1d75db3f062aafd81b148cbf4f4Test
https://doi.org/10.1038/s41375-018-0086-0Test

المؤلفون: Karin Tarte, Thomas E. Witzig, Imane Azzaoui, Thomas M. Habermann, Andrew L. Feldman, Céline Pangault, Noel Milpied, Stephen M. Ansell, Thierry Fest, Marie Parrens, Matthew J. Maurer, James R. Cerhan, Delphine Rossille, Mikael Roussel, Susan L. Slager, Thierry Lamy, Gaëlle Labouré, Brian K. Link

المساهمون: Microenvironment, Cell Differentiation, Immunology and Cancer (MICMAC), Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), CHU Pontchaillou [Rennes], Mayo Clinic [Rochester], CHU Bordeaux [Bordeaux], University of Iowa [Iowa City], This study is supported by the French Health Minister (BMS_LyTrans project, NCT01287923), the National Institute of Cancer (INCa Translational Research 2010), the French Lymphoma Study Association (LYSA), the French National Agency for Research (ANR Carnot/CALYM), the National Cancer Institute (P50 CA97274, R01 CA92153), and the Henry J Predolin Foundation. Concerning the French cohort, we are indebted to the LYSA pathology platform (Hôpital Henri Mondor, Créteil) for immunohistochemical experiments, the Centre de Ressources Biologiques CRB-Santé (BB-0033-00056) of the Rennes hospital for providing high quality samples. This work was partly supported by a French National Cancer Institute post-doctoral fellowship (grant number PDOC-RC-GO/07-003) to the first author (D.R.)., Université de Rennes (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Chard-Hutchinson, Xavier

المصدر: Leukemia
Leukemia, Nature Publishing Group: Open Access Hybrid Model Option B, 2017, 31 (4), pp.988-991. ⟨10.1038/leu.2016.385⟩
Leukemia, 2017, 31 (4), pp.988-991. ⟨10.1038/leu.2016.385⟩

مصطلحات موضوعية: Adult, Male, [SDV.MHEP.HEM] Life Sciences [q-bio]/Human health and pathology/Hematology, Cancer Research, medicine.medical_specialty, Adolescent, Programmed Cell Death 1 Receptor, [SDV.CAN]Life Sciences [q-bio]/Cancer, Article, Young Adult, 03 medical and health sciences, 0302 clinical medicine, [SDV.CAN] Life Sciences [q-bio]/Cancer, Refractory, immune system diseases, hemic and lymphatic diseases, Internal medicine, Biomarkers, Tumor, Tumor Microenvironment, medicine, Humans, ComputingMilieux_MISCELLANEOUS, Aged, Aged, 80 and over, Hematology, business.industry, Peripheral tolerance, [SDV.MHEP.HEM]Life Sciences [q-bio]/Human health and pathology/Hematology, Middle Aged, Prognosis, medicine.disease, 3. Good health, Lymphoma, Leukemia, Oncology, Apoptosis, 030220 oncology & carcinogenesis, Immunology, Cancer research, Female, Rituximab, Lymphoma, Large B-Cell, Diffuse, business, Diffuse large B-cell lymphoma, 030215 immunology, medicine.drug

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a0877267aca814536e5a4718fd95531Test
https://doi.org/10.1038/leu.2016.385Test

المؤلفون: Panu E. Kovanen, Kimmo Porkka, Sami Blom, Tero Aittokallio, Satu Mustjoki, Riku Turkki, Himanshu Chheda, Teijo Pellinen, Olli Dufva, Perttu Koskenvesa, Antonio Ribeiro, Oscar Brück, Olli Kallioniemi

المساهمون: Medicum, Department of Clinical Chemistry and Hematology, Clinicum, Department of Oncology, Hematologian yksikkö, University of Helsinki, Institute for Molecular Medicine Finland, HUSLAB, Department of Pathology, Doctoral Programme in Integrative Life Science, Doctoral Programme in Drug Research, Tero Aittokallio / Principal Investigator, Bioinformatics, Department of Medicine, Olli-Pekka Kallioniemi / Principal Investigator, Department of Diagnostics and Therapeutics, HUS Comprehensive Cancer Center, Precision Systems Medicine

المصدر: Leukemia. 32(7)

مصطلحات موضوعية: 0301 basic medicine, Male, Cancer Research, Biopsy, T-Lymphocytes, Leukocyte Count, 0302 clinical medicine, Immunophenotyping, Bone Marrow, T-Lymphocyte Subsets, hemic and lymphatic diseases, Tumor Microenvironment, Medicine, TREATMENT-FREE REMISSION, MOLECULAR RESPONSE, Cancer immunology, Aged, 80 and over, CHRONIC MYELOGENOUS LEUKEMIA, Myeloid leukemia, Hematology, Middle Aged, Flow Cytometry, Immunohistochemistry, 3. Good health, Leukemia, medicine.anatomical_structure, Treatment Outcome, Oncology, 030220 oncology & carcinogenesis, Absolute neutrophil count, Female, STEM-CELLS, Adult, 3122 Cancers, DISCONTINUATION, IMATINIB, DEATH 1, Immunomodulation, 03 medical and health sciences, Young Adult, Immune system, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Humans, Lymphocyte Count, CHRONIC MYELOID-LEUKEMIA, Protein Kinase Inhibitors, Aged, CHRONIC-PHASE, business.industry, Myeloid-Derived Suppressor Cells, Histocompatibility Antigens Class I, medicine.disease, 030104 developmental biology, Tissue Array Analysis, Immunology, T-CELLS, Bone marrow, business, Biomarkers, Chronic myelogenous leukemia

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6e158960303ae4a91970e77d2a50cabTest
https://pubmed.ncbi.nlm.nih.gov/29925907Test

المؤلفون: Wei Ding, Kimberly A. Gwin, Henan Zhang, Neil E. Kay, Sameer A. Parikh, Kay L. Medina, Charla R. Secreto, Bryce A. Manso, Molly G. Mikkelson

المصدر: Leukemia. 33(3)

مصطلحات موضوعية: 0301 basic medicine, Adult, Male, Cancer Research, CD34, Antigens, CD34, Bone Marrow Cells, Article, 03 medical and health sciences, 0302 clinical medicine, Immune system, Bone Marrow, hemic and lymphatic diseases, Proto-Oncogene Proteins, medicine, Humans, GATA1 Transcription Factor, Progenitor cell, Immunodeficiency, Aged, Aged, 80 and over, business.industry, Tumor Necrosis Factor-alpha, Hematology, Middle Aged, medicine.disease, Flow Cytometry, Hematopoietic Stem Cells, Hypoxia-Inducible Factor 1, alpha Subunit, Leukemia, Lymphocytic, Chronic, B-Cell, GATA2 Transcription Factor, Killer Cells, Natural, Leukemia, Haematopoiesis, 030104 developmental biology, medicine.anatomical_structure, Oncology, 030220 oncology & carcinogenesis, Immunology, Trans-Activators, Female, Bone marrow, business, Untreated Chronic Lymphocytic Leukemia

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::917395186311b006e447e92dc1f52854Test
https://pubmed.ncbi.nlm.nih.gov/30291337Test