A new device for inducing deep localized vaporization in liver with the Nd-YAG laser
| العنوان: | A new device for inducing deep localized vaporization in liver with the Nd-YAG laser |
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| المؤلفون: | J. J. Eledjam, C. Pignodel, A. Ould-Said, S. Rouy, G. Godlewski, P. Sambuc, J. M. Bourgeois |
| المصدر: | Lasers in Medical Science. 3:111-117 |
| بيانات النشر: | Springer Science and Business Media LLC, 1988. |
| سنة النشر: | 1988 |
| مصطلحات موضوعية: | Hyperthermia, medicine.medical_specialty, Materials science, business.industry, Ultrasound, Connective tissue, Dermatology, Laser, medicine.disease, Surgery, law.invention, Lesion, Core (optical fiber), medicine.anatomical_structure, law, Nd:YAG laser, Vaporization, medicine, medicine.symptom, business, Nuclear medicine |
| الوصف: | A new device, composed of a hand-piece (250 mm in length, and 5 mm in diameter) connected to a cooling circulation, has been developed for the purpose of inducing focal coagulation deep in the liver, using a high-power Nd-YAG laser. The device, guiding and protecting the optical fibre, withstands a power-setting of 100 W and allows means transmission of 80% during intrahepatic application with an average power density of 10 200 W/cm2. Thirty-six lesions of 12–18 mm in diameter were made in 11 pigs under ultrasound control with laser shorts of 80 W mean power output for 10s duration. Intrahepatic thermocouples showed a high rise in temperature in the core of the lesion, inducing vaporization, while moderate hyperthermia (54.4%C/60s on average), high enough for tumour cell kill, was observed 1 cm from the laser source. Immediately after irradiation ultrasound revealed a central echo-free lesion, well defined on day 3 by a hyperechoic border and invaded from day 20 by internal hyperechoic enhancement. Anatomical examination demonstrated, on day 0, an excavated site of vaporization which was surround, from day 3 on wards, by an increasing ring of connective tissue, and which was covered, from day 30 onwards, by a fibrotic network gaining ground towards the centre of the lesion. Good healing free of complications, was observed after four months' follow-up. The technique is proposed for photocoagulation of deep metastases. |
| تدمد: | 1435-604X 0268-8921 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_________::0644905bc24ae24ae6b573b496b49756Test https://doi.org/10.1007/bf02593798Test |
| حقوق: | CLOSED |
| رقم الانضمام: | edsair.doi...........0644905bc24ae24ae6b573b496b49756 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 1435604X 02688921 |
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