Computed tomography coronary angiography in asymptomatic patients
| العنوان: | Computed tomography coronary angiography in asymptomatic patients |
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| المؤلفون: | Onofrio A. Catalano, R. De Rosa, Alfredo Blandino, Ignazio Salamone, A. Palumbo, Massimo Midiri, Annick C. Weustink, Erica Maffei, Teresa Arcadi, Filippo Cademartiri, Chiara Martini, Ludovico La Grutta, Carlo Tedeschi, Roberto Malago, Nico R. Mollet |
| المساهمون: | Radiology & Nuclear Medicine, Cardiology, Maffei, E, Palumbo, A, Martini, C, Tedeschi, C, Arcadi, T, La Grutta, L, Malagò, R, Weustink, AC, Mollet, NR, De Rosa, R, Catalano, O, Salamone, I, Blandino, A, Midiri, M, Cademartiri, F |
| المصدر: | Europe PubMed Central Radiologia Medica, 116(8), 1161-1173. Springer-Verlag Italia |
| بيانات النشر: | Springer Science and Business Media LLC, 2011. |
| سنة النشر: | 2011 |
| مصطلحات موضوعية: | Adult, Male, Coronary angiography, medicine.medical_specialty, Coronary Angiography, Risk Assessment, Sensitivity and Specificity, Coronary artery disease, Asymptomatic, Computed tomography coronary angiography, Diagnosis, Differential, SDG 3 - Good Health and Well-being, Predictive Value of Tests, Risk Factors, Outpatients, Prevalence, medicine, Humans, Radiology, Nuclear Medicine and imaging, Sicily, Aged, Neuroradiology, Primary prevention, Computed tomography coronary angiography, Conventional coronary angiography, Asymptomatic, Primary prevention, Coronary artery disease, medicine.diagnostic_test, business.industry, Ultrasound, Coronary Stenosis, Calcinosis, Interventional radiology, General Medicine, Middle Aged, Conventional coronary angiography, medicine.disease, Predictive value of tests, Female, Tomography, Radiology, medicine.symptom, Settore MED/36 - Diagnostica Per Immagini E Radioterapia, Tomography, X-Ray Computed, business, CARDIAC CT |
| الوصف: | This study assessed the accuracy of computed tomography coronary angiography (CT-CA) for detecting significant coronary artery disease (CAD; a parts per thousand yen50% lumen reduction) in intermediate/high-risk asymptomatic patients. A total of 183 consecutive asymptomatic individuals (92 men; mean age 54 +/- 11 years) with more than one major risk factor (obesity, hypertension, diabetes, hypercholesterolaemia, family history, smoking) and an inconclusive or nonfeasible noninvasive stress test result (stress electrocardiography, stress echocardiography, nuclear stress scintigraphy) underwent CT-CA in an outpatient setting. All patients underwent conventional coronary angiography (CAG) within 4 weeks. Data from CT-CA were compared with CAG regarding the presence of significant CAD (a parts per thousand yen50% lumen reduction). Mean calcium score was 177 +/- 432, mean heart rate during the CT-CA scan was 58 +/- 8 bpm and the prevalence (per-patient) of obstructive CAD was 19%. CT-CA showed single-vessel CAD in 9% of patients, two-vessel CAD in 9% and three-vessel CAD in 0%. Per-patient sensitivity, specificity, positive predictive value and negative predictive value of CT-CA were 100% (90-100), 98% (96-99), 97% (85-99), 100% (97-100), respectively. Positive and negative likelihood ratios were 151 and 0, respectively. CT-CA is an excellent noninvasive imaging modality for excluding significant CAD in intermediate/ high-risk asymptomatic patients with inconclusive or nonfeasible noninvasive stress test. |
| تدمد: | 1826-6983 0033-8362 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bff18dae9d34a2826bcedb0ffb72123Test https://doi.org/10.1007/s11547-011-0723-4Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....6bff18dae9d34a2826bcedb0ffb72123 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 18266983 00338362 |
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