Evaluation of low-dose dual energy computed tomography for in vivo assessment of renal/ureteric calculus composition
| العنوان: | Evaluation of low-dose dual energy computed tomography for in vivo assessment of renal/ureteric calculus composition |
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| المؤلفون: | Shrawan Kumar Singh, Anupam Lal, Niranjan Khandelwal, Arup K. Mandal, Harshavardhan Mahalingam, Shalmoli Bhattacharyya |
| المصدر: | Korean Journal of Urology |
| بيانات النشر: | The Korean Urological Association, 2015. |
| سنة النشر: | 2015 |
| مصطلحات موضوعية: | Adult, Male, medicine.medical_specialty, Ureteral Calculi, Struvite, Urinary system, Calcium oxalate, Magnesium Compounds, urologic and male genital diseases, Radiation Dosage, Phosphates, chemistry.chemical_compound, Kidney Calculi, Young Adult, Urolithiasis, In vivo, Hounsfield scale, Apatites, Image Interpretation, Computer-Assisted, medicine, Image noise, Humans, Prospective Studies, Calculus (medicine), X-ray computed tomography, Receiver operating characteristic, Calcium Oxalate, business.industry, Dual-Energy Computed Tomography, Middle Aged, medicine.disease, Surgery, Uric Acid, chemistry, Endourology/Urolithiasis, Original Article, Female, Waist Circumference, Nuclear medicine, business, Tomography, X-Ray Computed, human activities |
| الوصف: | Purpose This study aimed to assess the accuracy of low-dose dual-energy computed tomography (DECT) in predicting the composition of urinary calculi. Materials and Methods A total of 52 patients with urinary calculi were scanned with a 128-slice dual-source DECT scanner by use of a low-dose protocol. Dual-energy (DE) ratio, weighted average Hounsfield unit (HU) of calculi, radiation dose, and image noise levels were recorded. Two radiologists independently rated study quality. Stone composition was assessed after extraction by Fourier transform infrared spectroscopy (FTIRS). Analysis of variance was used to determine if the differences in HU values and DE ratios between the various calculus groups were significant. Threshold cutoff values to classify the calculi into separate groups were identified by receiver operating characteristic curve analysis. Results A total of 137 calculi were detected. FTIRS analysis differentiated the calculi into five groups: uric acid (n=17), struvite (n=3), calcium oxalate monohydrate and dihydrate (COM-COD, n=84), calcium oxalate monohydrate (COM, n=28), and carbonate apatite (n=5). The HU value could differentiate only uric acid calculi from calcified calculi (p80% sensitivity and specificity to differentiate them. The DE ratio could not differentiate COM from COM-COD calculi. No study was rated poor in quality by either of the observers. The mean radiation dose was 1.8 mSv. Conclusions Low-dose DECT accurately predicts urinary calculus composition in vivo while simultaneously reducing radiation exposure without compromising study quality. |
| اللغة: | English |
| تدمد: | 2005-6745 2005-6737 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6631d5f0f230ccd972c4d9afec805351Test http://europepmc.org/articles/PMC4534433Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....6631d5f0f230ccd972c4d9afec805351 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20056745 20056737 |
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