نتائج البحث

1

Type 1 diabetic mellitus patients with increased atherosclerosis risk display decreased CDKN2A/2B/2BAS gene expression in leukocytes

المؤلفون: Herminia González-Navarro, Juan F. Ascaso, Verónica Sánchez-García, Andrea Herrero-Cervera, Ángela Vinué, Sergio Martínez-Hervás, Deborah J. Burks, José T. Real

المصدر: Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-12 (2019)
Martínez Hervás, Sergio Sánchez-García, Verónica Herrero-Cervera, Andrea Vinué Visús, María Ángela Real Collado, José Tomás Ascaso Gimilio, Juan Francisco Burks, Deborah Jane González Navarro, Herminia 2019 Type 1 diabetic mellitus patientswith increased atherosclerosisriskdisplay decreased CDKN2A/2B/2BAS gene expression in leukocytes Journal Of Translational Medicine 17 1 222
Journal of Translational Medicine
RODERIC. Repositorio Institucional de la Universitat de Valéncia
instname

مصطلحات موضوعية: Blood Glucose, 0301 basic medicine, endocrine system diseases, Cellular differentiation, lcsh:Medicine, 0302 clinical medicine, Risk Factors, RAR-related orphan receptor gamma, immune system diseases, Leukocytes, IL-2 receptor, Diabetis, FOXP3, Cell Differentiation, General Medicine, Type 1 diabetes, 030220 oncology & carcinogenesis, Cytokines, RNA, Long Noncoding, medicine.symptom, Adult, medicine.medical_specialty, CD14, T cells, Inflammation, Peripheral blood mononuclear cell, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Internal medicine, medicine, Humans, RNA, Messenger, Cyclin-Dependent Kinase Inhibitor p16, Cyclin-Dependent Kinase Inhibitor p15, Glycated Hemoglobin, business.industry, Research, lcsh:R, Atherosclerosis, medicine.disease, Cardiovascular risk, Diabetes Mellitus, Type 1, 030104 developmental biology, Endocrinology, Gene Expression Regulation, Case-Control Studies, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11f8d1c14c7b49302adbadd1e70fe7b9Test
http://link.springer.com/article/10.1186/s12967-019-1977Test-1

2

Transient receptor potential melastatin 2 channels are overexpressed in myalgic encephalomyelitis/chronic fatigue syndrome patients

المؤلفون: Hélène Cabanas, Donald Staines, Sonya Marshall-Gradisnik, Cassandra Balinas

المصدر: Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-11 (2019)
Journal of Translational Medicine

مصطلحات موضوعية: 0301 basic medicine, Interleukin 2, Adult, Cytotoxicity, Immunologic, Male, Encephalomyelitis, Cell, TRPM Cation Channels, lcsh:Medicine, Stimulation, CD38, General Biochemistry, Genetics and Molecular Biology, Flow cytometry, 03 medical and health sciences, 0302 clinical medicine, medicine, Humans, TRPM2, Adenosine diphosphate ribose, Cyclic ADP-Ribose, Fatigue Syndrome, Chronic, biology, medicine.diagnostic_test, Chemistry, Research, lcsh:R, General Medicine, medicine.disease, ADP-ribosyl Cyclase 1, Killer Cells, Natural, Transient receptor potential melastatin 2, 030104 developmental biology, medicine.anatomical_structure, Myalgic encephalomyelitis/chronic fatigue syndrome, 030220 oncology & carcinogenesis, biology.protein, Cancer research, Interleukin-2, Natural killer cells, Female, Calcium, Antibody, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9e60c5262fe2d0a51f9918ac96c8c52Test
https://doaj.org/article/8cbd2da5d83c47c881241e44a3db55d5Test

3

Identification of susceptibility loci for cardiovascular disease in adults with hypertension, diabetes, and dyslipidemia

المؤلفون: Da-Hyun Park, Yu-Jin Kwon, Ji-Won Lee, Seong-Jin Kim, Hyuk Jae Chang, Jung Oh Kim, Ja-Eun Choi, Jae-Min Park, Kyung-Won Hong, Youhyun Song

المصدر: Journal of Translational Medicine
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-11 (2021)

مصطلحات موضوعية: Adult, 0301 basic medicine, medicine.medical_specialty, Population, lcsh:Medicine, Polycomb-Group Proteins, Single-nucleotide polymorphism, Genome-wide association study, Coronary Artery Disease, Protein Serine-Threonine Kinases, 030204 cardiovascular system & hematology, Genome-wide association studies, General Biochemistry, Genetics and Molecular Biology, Ligases, 03 medical and health sciences, Diabetes mellitus, 0302 clinical medicine, Risk Factors, Internal medicine, Epidemiology, medicine, Humans, cardiovascular diseases, Prospective Studies, Prospective cohort study, education, Dyslipidemias, Polycomb Repressive Complex 1, education.field_of_study, business.industry, Research, lcsh:R, General Medicine, Cardiovascular disease, medicine.disease, 030104 developmental biology, Dyslipidemia, Cardiovascular Diseases, Hypertension, Cohort, business, Genome-Wide Association Study

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6512dba72848ad63d8ae6fdd8b2bab4Test
https://doi.org/10.1186/s12967-021-02751-3Test

4

Overexpression of microRNA-195-5p reduces cisplatin resistance and angiogenesis in ovarian cancer by inhibiting the PSAT1-dependent GSK3β/β-catenin signaling pathway

المؤلفون: Beihua Kong, Jun Dai, Peihai Zhang, Rujia Wei

المصدر: Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-17 (2019)
Journal of Translational Medicine

مصطلحات موضوعية: 0301 basic medicine, Angiogenesis, lcsh:Medicine, Carcinoma, Ovarian Epithelial, Mice, 0302 clinical medicine, Gene expression, Tumor Cells, Cultured, Phosphoserine aminotransferase 1, Wnt Signaling Pathway, beta Catenin, Aged, 80 and over, Ovarian Neoplasms, Mice, Inbred BALB C, Neovascularization, Pathologic, Chemistry, General Medicine, Middle Aged, Gene Expression Regulation, Neoplastic, 030220 oncology & carcinogenesis, Phosphorylation, Female, Signal transduction, medicine.drug, Adult, Mice, Nude, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, In vivo, Ovarian cancer, microRNA, medicine, Animals, Humans, Transaminases, Cisplatin resistance, Aged, Cisplatin, Glycogen Synthase Kinase 3 beta, Research, lcsh:R, Glycogen synthase kinase-3β/β-catenin signaling pathway, MicroRNA-195-5p, Xenograft Model Antitumor Assays, MicroRNAs, HEK293 Cells, 030104 developmental biology, Drug Resistance, Neoplasm, Apoptosis, Cancer research

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4039825f13f3d1acbbe641200a5ffac0Test
http://link.springer.com/article/10.1186/s12967-019-1932Test-1

5

Enhanced AZIN1 RNA editing and overexpression of its regulatory enzyme ADAR1 are important prognostic biomarkers in gastric cancer

المؤلفون: Junichiro Hiro, Akira Yamamoto, Chengzeng Yin, Masato Kusunoki, Masaki Ohi, Shigeyuki Yoshiyama, Yuji Toiyama, Tsunehiko Shigemori, Ajay Goel, Takashi Ichikawa, Yoshinaga Okugawa, Kunitoshi Shigeyasu, Toshimitsu Araki, Hiromi Yasuda, Hiroyuki Fujikawa

المصدر: Journal of Translational Medicine, Vol 16, Iss 1, Pp 1-11 (2018)
Journal of Translational Medicine

مصطلحات موضوعية: 0301 basic medicine, Male, RNA editing, Adenosine Deaminase, AZIN1, lcsh:Medicine, Risk Factors, Medicine, Antizyme inhibitor 1, Aged, 80 and over, biology, RNA-Binding Proteins, General Medicine, Middle Aged, Prognosis, 3. Good health, Gene Expression Regulation, Neoplastic, Real-time polymerase chain reaction, Treatment Outcome, Lymphatic Metastasis, Disease Progression, Female, Adult, Adolescent, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Young Adult, Stomach Neoplasms, Biomarkers, Tumor, Humans, Clinical significance, Aged, Lymph node metastasis, business.industry, Research, lcsh:R, RNA, Cancer, Odds ratio, medicine.disease, Survival Analysis, 030104 developmental biology, ADAR, Multivariate Analysis, Peritoneal metastasis, Cancer research, biology.protein, Neoplasm Recurrence, Local, business, Carrier Proteins, Gastric cancer

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dd98de332cd433f8dd3e360da82bb12Test
http://link.springer.com/article/10.1186/s12967-018-1740-zTest

6

CD25 and TGF-β blockade based on predictive integrated immune ratio inhibits tumor growth in pancreatic cancer

المؤلفون: Dayong Jin, Abulimiti Nuerxiati, Ning Pu, Wenchuan Wu, Guochao Zhao, Wenhui Lou, Jian-ang Li, Xuefeng Xu, Tiantao Kuang, Hanlin Yin, Dansong Wang

المصدر: Journal of Translational Medicine, Vol 16, Iss 1, Pp 1-13 (2018)
Journal of Translational Medicine

مصطلحات موضوعية: 0301 basic medicine, Male, medicine.medical_treatment, Programmed Cell Death 1 Receptor, lcsh:Medicine, CD8-Positive T-Lymphocytes, T-Lymphocytes, Regulatory, B7-H1 Antigen, Pancreatic ductal adenocarcinoma, 0302 clinical medicine, Transforming Growth Factor beta, IL-2 receptor, Aged, 80 and over, Tissue microarray, FOXP3, Forkhead Transcription Factors, General Medicine, Middle Aged, Prognosis, Tumor Burden, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Female, Immunotherapy, Carcinoma, Pancreatic Ductal, Adult, Combination therapy, Regulatory T cell, Adenocarcinoma, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Lymphocytes, Tumor-Infiltrating, Pancreatic cancer, medicine, Animals, Humans, Aged, Cell Proliferation, business.industry, Tumor-infiltrating lymphocytes, Research, lcsh:R, Interleukin-2 Receptor alpha Subunit, medicine.disease, Survival Analysis, Mice, Inbred C57BL, Pancreatic Neoplasms, Disease Models, Animal, Program death receptor-1, 030104 developmental biology, Integrated immune ratio, Multivariate Analysis, Cancer research, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3277a2c13a353914c2ebdbf213cc87eTest
http://link.springer.com/article/10.1186/s12967-018-1673-6Test

7

Wolfram syndrome, a rare neurodegenerative disease: from pathogenesis to future treatment perspectives

المؤلفون: Giorgia Tascini, Roberta Crispoldi, Susanna Esposito, Ursula Grohmann, Maria Teresa Pallotta, Giada Mondanelli, Ciriana Orabona

المصدر: Journal of Translational Medicine
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-12 (2019)

مصطلحات موضوعية: 0301 basic medicine, Male, lcsh:Medicine, Type 2 diabetes, Disease, Review, Deafness, Bioinformatics, Endoplasmic Reticulum, 0302 clinical medicine, Diabetes insipidus, Optic atrophy, Type 1 diabetes, WFS1, WFS2, Wolfram syndrome, Child, Clinical Trials as Topic, Neurodegeneration, Genetic disorder, Neurodegenerative Diseases, General Medicine, Prognosis, 030220 oncology & carcinogenesis, Child, Preschool, Disease Progression, Female, Adult, Adolescent, Genes, Recessive, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Young Adult, Atrophy, Drug Development, Diabetes mellitus, medicine, Humans, business.industry, lcsh:R, Drug Repositioning, Infant, Membrane Proteins, medicine.disease, 030104 developmental biology, Diabetes Mellitus, Type 1, Etiology, Quality of Life, Interdisciplinary Communication, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::760c8a15a6df3b9cd9d46737332a66acTest
https://pubmed.ncbi.nlm.nih.gov/31337416Test

8

Circulating miR-3659 may be a potential biomarker of dyslipidemia in patients with obesity

المؤلفون: De Zhai Yang, Shuo Yang, Wei Xiong Lin, Liu Miao, Shang Ling Pan, Rui-Xing Yin

المصدر: Journal of Translational Medicine
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-10 (2019)

مصطلحات موضوعية: 0301 basic medicine, Male, COL1A1, lcsh:Medicine, Gene Expression Omnibus, 0302 clinical medicine, Weighted gene co-expression network analysis, Cluster Analysis, Gene Regulatory Networks, Protein Interaction Maps, 3' Untranslated Regions, Aged, 80 and over, General Medicine, Middle Aged, 030220 oncology & carcinogenesis, Female, Adult, Adolescent, Single-nucleotide polymorphism, Computational biology, Biology, Polymorphism, Single Nucleotide, General Biochemistry, Genetics and Molecular Biology, Collagen Type I, 03 medical and health sciences, Young Adult, microRNA, medicine, Humans, Obesity, Circulating MicroRNA, KEGG, Gene, Aged, Dyslipidemias, Base Sequence, Microarray analysis techniques, Research, lcsh:R, Molecular Sequence Annotation, medicine.disease, Collagen Type I, alpha 1 Chain, Collagen, type I, alpha 1, 030104 developmental biology, Gene Ontology, Dyslipidemia, ROC Curve, miR-3659, Biomarkers

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54841fda2fd3d97bc10a164dac0152eeTest
http://europepmc.org/articles/PMC6332685Test

9

Selective pharmacological inhibition of DDR1 prevents experimentally-induced glomerulonephritis in prevention and therapeutic regime

المصدر: Journal of Translational Medicine, Vol 16, Iss 1, Pp 1-20 (2018)
Journal of Translational Medicine, Vol. 16, No 1 (2018) P. 148
Journal of Translational Medicine
Journal of translational medicine 16(1), 148 (2018). doi:10.1186/s12967-018-1524-5

مصطلحات موضوعية: 0301 basic medicine, Male, 030232 urology & nephrology, lcsh:Medicine, ddc:616.07, Kidney, Receptor tyrosine kinase, Epithelium, Podocyte, Mice, 0302 clinical medicine, Glomerulonephritis, Glomerulosclerosis, Gene Regulatory Networks, Receptor, Regulation of gene expression, Aged, 80 and over, biology, General Medicine, Middle Aged, medicine.anatomical_structure, Phenotype, Female, Adult, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Discoidin Domain Receptor 1, medicine, CKD, Gene silencing, Animals, Humans, Aged, Inflammation, DDR1 inhibition, DDR1, business.industry, Research, Gene Expression Profiling, lcsh:R, Epithelial Cells, Gene signature, medicine.disease, Fibrosis, Disease Models, Animal, 030104 developmental biology, Gene Expression Regulation, Cancer research, biology.protein, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48473b0f4a7ce5837acf3a101aafd6f5Test
http://link.springer.com/article/10.1186/s12967-018-1524-5Test

10

Undetectable circulating tumor DNA (ctDNA) levels correlate with favorable outcome in metastatic melanoma patients treated with anti-PD1 therapy

المؤلفون: Hendrik Everaert, Danielle Lienard, Bart Neyns, Gil Awada, Simon Planken, Marleen Keyaerts, Hakim El Housni, Véronique Del Marmol, Pierre Heimann, Hassane Njimi, Mélanie Delaunoy, Julia Katharina Schwarze, Teofila Seremet, Yanina Jansen

المساهمون: Surgery, Faculty of Medicine and Pharmacy, Clinical sciences, Internal Medicine, Supporting clinical sciences, Medical Imaging, Nuclear Medicine, Medical Oncology, Laboratory for Medical and Molecular Oncology, Laboratory of Molecullar and Cellular Therapy

المصدر: Journal of Translational Medicine
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-13 (2019)
Journal of translational medicine, 17 (1

مصطلحات موضوعية: Central Nervous System, Male, 0301 basic medicine, Oncology, medicine.medical_treatment, Programmed Cell Death 1 Receptor, lcsh:Medicine, Kaplan-Meier Estimate, 0302 clinical medicine, Cost of Illness, Favorable outcome, Neoplasm Metastasis, Anti pd1, Melanoma, NRAS mutations monitoring, Medicine(all), Hazard ratio, General Medicine, Sciences bio-médicales et agricoles, Middle Aged, Treatment Outcome, Circulating tumor DNA, 030220 oncology & carcinogenesis, Female, Immunotherapy, Biologie, Adult, medicine.medical_specialty, Monitoring, Metastatic melanoma, medicine.drug_class, Monoclonal antibody, General Biochemistry, Genetics and Molecular Biology, BRAF, 03 medical and health sciences, Internal medicine, BRAF/NRAS mutations monitoring, medicine, Humans, Liquid biopsy, Aged, business.industry, Research, lcsh:R, Translational research, 030104 developmental biology, Multivariate Analysis, Mutation, business, Follow-Up Studies

وصف الملف: 1 full-text file(s): application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a6bbc4e61b7332e00b567ee9e5508abTest
https://doi.org/10.1186/s12967-019-2051-8Test

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