دورية أكاديمية

Clinical parameters and treatment outcome in patients of acromegaly: A retrospective analysis of 51 patients

التفاصيل البيبلوغرافية
العنوان: Clinical parameters and treatment outcome in patients of acromegaly: A retrospective analysis of 51 patients
المؤلفون: Shahid Ahmed, Ahmed Tashfeen Ashraf, Muhammad Junaid Mushtaq, Zujaja Hina Haroon
المصدر: Journal of the Pakistan Medical Association, Vol 72, Iss 2 (2022)
بيانات النشر: Pakistan Medical Association, 2022.
سنة النشر: 2022
المجموعة: LCC:Medicine
مصطلحات موضوعية: Medicine
الوصف: The aim of the study was to analyze the pattern of clinical presentation and management outcome in patients of acromegaly. It is a cross-sectional study based on the clinical records of 51 patients of Acromegaly. All the recorded clinical data was analyzed to see the pattern of clinical presentation and management outcome. IBM SPSS statistics version 22 was used for statistical analysis. The median age was 32 years. Twenty seven patients underwent surgery and 6 (22.2%) achieved remission. With pharmacological management, 35.8% patients achieved control of the disease with Octreotide LAR and 7.1% with cabergoline. Eighteen patients were treated with External Beam Radiation (EBR) and Stereotactic Radiosurgery (SRS). Remission rate has been 88.9% with SRS and 33.3% with EBR. The study shows higher prevalence of Growth Hormone (GH) secreting tumour in younger people and men. Remission rate was highest in patients treated with radiotherapy after partial response to TSS. Keywords: Acromegaly, trans-sphenoidal surgery, radiotherapy, Octreotide. Continuous...
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 0030-9982
العلاقة: https://www.ojs.jpma.org.pk/index.php/public_html/article/view/2104Test; https://doaj.org/toc/0030-9982Test
DOI: 10.47391/JPMA.2104
الوصول الحر: https://doaj.org/article/8eb5c8a0541c477891b9039e6d956b4cTest
رقم الانضمام: edsdoj.8eb5c8a0541c477891b9039e6d956b4c
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:00309982
DOI:10.47391/JPMA.2104