BackgroundIt is unclear whether achieving multiple risk factor (RF) goals through protocol-guided intensive medical therapy is feasible or improves outcomes in type 2 diabetes mellitus.ObjectivesThis study sought to quantify the relationship between achieved RF goals in the BARI 2D (Bypass Angioplasty Investigation Revascularization 2 Diabetes) trial and cardiovascular events/survival.MethodsWe performed a nonrandomized analysis of survival/cardiovascular events and control of 6 RFs (no smoking, non–high-density lipoprotein cholesterol