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1دورية أكاديمية
المؤلفون: Yoo, Euna, Stokes, Barbara H, de Jong, Hanna, Vanaerschot, Manu, Kumar, TRS, Lawrence, Nina, Njoroge, Mathew, Garcia, Arnold, Van der Westhuyzen, Renier, Momper, Jeremiah D, Ng, Caroline L, Fidock, David A, Bogyo, Matthew
المصدر: Journal of the American Chemical Society. 140(36)
مصطلحات موضوعية: Infectious Diseases, Malaria, Vector-Borne Diseases, Rare Diseases, Orphan Drug, 5.1 Pharmaceuticals, Development of treatments and therapeutic interventions, Infection, Good Health and Well Being, Artemisinins, Dose-Response Relationship, Drug, Molecular Structure, Plasmodium falciparum, Proteasome Endopeptidase Complex, Proteasome Inhibitors, Structure-Activity Relationship, Chemical Sciences, General Chemistry
وصف الملف: application/pdf
الوصول الحر: https://escholarship.org/uc/item/7962n5cxTest
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2دورية أكاديمية
المؤلفون: Su, Jing, Chen, Feng, Cryns, Vincent L, Messersmith, Phillip B
المصدر: Journal of the American Chemical Society. 133(31)
مصطلحات موضوعية: Biotechnology, Cancer, Bioengineering, Breast Cancer, Development of treatments and therapeutic interventions, 5.1 Pharmaceuticals, Antineoplastic Agents, Boronic Acids, Bortezomib, Catechols, Cell Death, Cell Line, Tumor, Cell Proliferation, Cell Survival, Dose-Response Relationship, Drug, Drug Carriers, Drug Delivery Systems, Drug Screening Assays, Antitumor, Humans, Hydrogen-Ion Concentration, Molecular Structure, Polymers, Proteasome Endopeptidase Complex, Proteasome Inhibitors, Pyrazines, Structure-Activity Relationship, Chemical Sciences, General Chemistry
وصف الملف: application/pdf
الوصول الحر: https://escholarship.org/uc/item/1p58j5khTest
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3
المؤلفون: Kristen A. Baltgalvis, Vincent M. Crowley, Michael A. Schafroth, Brian E. Nordin, Benjamin F. Cravatt, Christie L Eissler, Joe L Rodriguez, Shota Kikuchi, Xiaoyu Zhang, Thomas G Wucherpfennig, Todd Kinsella, Kent T Symons, Melissa M. Dix, David S. Weinstein, Dean Stamos, Gabriel M. Simon, Yu Yamashita, Ludwig Bauer, Lena M Luukkonen
المصدر: J Am Chem Soc
مصطلحات موضوعية: Male, Proteasome Endopeptidase Complex, Proteolysis, Protein degradation, 010402 general chemistry, 01 natural sciences, Biochemistry, Article, Catalysis, Chimera (genetics), Colloid and Surface Chemistry, Cell Line, Tumor, medicine, Humans, Receptor, medicine.diagnostic_test, biology, Ubiquitin, Chemistry, Prostatic Neoplasms, Ubiquitin-Protein Ligase Complexes, General Chemistry, 0104 chemical sciences, Ubiquitin ligase, Cell biology, Androgen receptor, Receptors, Androgen, Cell culture, Cancer cell, biology.protein
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9801b3a3bafd3e374259ca9ad1a1524Test
https://doi.org/10.1021/jacs.1c00990Test -
4
المؤلفون: Jiao Zhou, Arjun Saha, Ziwei Huang, Arieh Warshel
المصدر: J Am Chem Soc
مصطلحات موضوعية: Proteasome Endopeptidase Complex, SARS-CoV-2, General Chemistry, Biochemistry, Antiviral Agents, Catalysis, Article, COVID-19 Drug Treatment, Molecular Docking Simulation, Colloid and Surface Chemistry, Humans, Protease Inhibitors, Pandemics, Coronavirus 3C Proteases
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7674d061746987eb15924e05325e51c3Test
https://pubmed.ncbi.nlm.nih.gov/35436404Test -
5
المؤلفون: Nathaniel J. Henning, Andrew G. Manford, Jessica N. Spradlin, Scott M. Brittain, Erika Zhang, Jeffrey M. McKenna, John A. Tallarico, Markus Schirle, Michael Rape, Daniel K. Nomura
المصدر: J Am Chem Soc
مصطلحات موضوعية: Proteasome Endopeptidase Complex, Binding Sites, Dasatinib, Fusion Proteins, bcr-abl, Ubiquitin-Protein Ligase Complexes, Cell Cycle Proteins, General Chemistry, Azepines, Triazoles, Biochemistry, Catalysis, Recombinant Proteins, Article, Cell Line, Mice, Colloid and Surface Chemistry, Acetamides, Proteolysis, Animals, Humans, Cysteine, Carrier Proteins, Protein Kinase Inhibitors, Protein Binding, Transcription Factors
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::883c232f223b56eeda2a0e64db5426bfTest
https://pubmed.ncbi.nlm.nih.gov/34994556Test -
6
المؤلفون: Hanna De Jong, Caroline L. Ng, Nina Lawrence, Arnold Garcia, Manu Vanaerschot, T. R.S. Kumar, Matthew Bogyo, Jeremiah D. Momper, Euna Yoo, Renier van der Westhuyzen, David A. Fidock, Mathew Njoroge, Barbara H. Stokes
المصدر: Journal of the American Chemical Society, vol 140, iss 36
مصطلحات موضوعية: 0301 basic medicine, Proteasome Endopeptidase Complex, Plasmodium falciparum, High selectivity, Peptide binding, Computational biology, 01 natural sciences, Biochemistry, Plasmodium, Article, Catalysis, Dose-Response Relationship, Structure-Activity Relationship, 03 medical and health sciences, Rare Diseases, Colloid and Surface Chemistry, medicine, Structure–activity relationship, Artemisinin, Enhanced selectivity, Dose-Response Relationship, Drug, Molecular Structure, biology, 010405 organic chemistry, Extramural, Chemistry, General Chemistry, biology.organism_classification, Artemisinins, Malaria, 0104 chemical sciences, Vector-Borne Diseases, Infectious Diseases, Orphan Drug, Good Health and Well Being, 030104 developmental biology, Proteasome, 5.1 Pharmaceuticals, Chemical Sciences, Drug, Development of treatments and therapeutic interventions, Infection, Proteasome Inhibitors, medicine.drug
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2de9fe299bdc9ec131d773b85cc71d37Test
https://doi.org/10.1021/jacs.8b06656Test -
7
المؤلفون: Zaizai Dong, Shumu Li, Song Yongmei, Zhen Zhang, Libo Zhao, Li Xu, Hongyu Yuan, Wei Zhou, Sun Guogui, Xiaohong Fang
المصدر: Journal of the American Chemical Society. 141(46)
مصطلحات موضوعية: Proteasome Endopeptidase Complex, Lung Neoplasms, Aptamer, Druggability, Mice, Nude, Adenocarcinoma of Lung, Antineoplastic Agents, Mitochondrion, 010402 general chemistry, Leucine-Rich Repeat Proteins, 01 natural sciences, Biochemistry, Catalysis, Small Molecule Libraries, Colloid and Surface Chemistry, medicine, Animals, Humans, Protein Interaction Maps, Protein kinase A, Gene knockdown, Chemistry, Proteins, General Chemistry, Aptamers, Nucleotide, medicine.disease, Small molecule, 0104 chemical sciences, Proteasome, A549 Cells, Cancer research, Adenocarcinoma, Drug Screening Assays, Antitumor
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b54cc064b64c852675b3f1a2278eee29Test
https://pubmed.ncbi.nlm.nih.gov/31657561Test -
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المؤلفون: Sumeet K. Singh, Ashraf Brik, Michael H. Glickman, Oded Kleifeld, Sachitanand M. Mali, Hosahalli P. Hemantha, Indrajit Sahu
المصدر: Journal of the American Chemical Society. 138:16004-16015
مصطلحات موضوعية: 0301 basic medicine, chemistry.chemical_classification, Proteasome Endopeptidase Complex, Isopeptide bond, Deubiquitinating Enzymes, Molecular Structure, Ubiquitin, Chemistry, Substrate (chemistry), General Chemistry, Cleavage (embryo), Ubiquitinated Proteins, Biochemistry, Catalysis, Cell biology, 03 medical and health sciences, Chain length, 030104 developmental biology, Colloid and Surface Chemistry, Proteasome, Humans, Degradation (geology), Deubiquitination
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83e496580589e6408990ff6931175853Test
https://doi.org/10.1021/jacs.6b09611Test -
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المؤلفون: Bo-Tao Xin, Gerjan de Bruin, Herman S. Overkleeft, Bogdan I. Florea
المصدر: Journal of the American Chemical Society. 138:9874-9880
مصطلحات موضوعية: 0301 basic medicine, Cytoplasm, Proteasome Endopeptidase Complex, Protein subunit, 7. Clean energy, 01 natural sciences, Biochemistry, Protein Structure, Secondary, Catalysis, 03 medical and health sciences, Colloid and Surface Chemistry, Protein structure, Fluorescence Resonance Energy Transfer, Humans, Binding site, Fluorescent Dyes, Binding Sites, 010405 organic chemistry, Chemistry, Native Polyacrylamide Gel Electrophoresis, General Chemistry, Core Particle, 0104 chemical sciences, 030104 developmental biology, Förster resonance energy transfer, Proteasome, Composition (visual arts), Proteasome Inhibitors, HeLa Cells
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f497831ad879fee3472b1747de042e7Test
https://doi.org/10.1021/jacs.6b04207Test -
10
المؤلفون: Michael Groll, Alberto Plaza, Rolf Müller, Christian Dubiella, Lena Keller, Marcel Kaiser
المصدر: Journal of the American Chemical Society. 137:8121-8130
مصطلحات موضوعية: Models, Molecular, Proteasome Endopeptidase Complex, In silico, Biochemistry, Mass Spectrometry, Catalysis, Condensation domain, chemistry.chemical_compound, Colloid and Surface Chemistry, Epoxomicin, Anti-Infective Agents, Thioesterase, Drug Discovery, Gene cluster, Humans, Myxococcales, Nuclear Magnetic Resonance, Biomolecular, Phylogeny, Glutamine amidotransferase, Drug discovery, General Chemistry, Biosynthetic Pathways, Proteasome, chemistry, Multigene Family, Peptides, Proteasome Inhibitors, Chromatography, Liquid
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::148bfb144a28646a6b130a50b85ab9d2Test
https://doi.org/10.1021/jacs.5b03833Test