المؤلفون: Gossec, Laure, Hawker, Gillian, Davis, Aileen M., Maillefert, Jean Francis, Lohmander, Stefan, Altman, Roy, Cibere, Jolanda, Conaghan, Philip G., Hochberg, Marc C., Jordan, Joanne M., Katz, Jeffrey N., March, Lyn, Mahomed, Nizar, Pavelka, Karel, Roos, Ewa, Suarez-Almazor, Maria E., Zanoli, Gustavo, Dougados, Maxime

المصدر: Journal of Rheumatology. 34(6):1432-1435

مصطلحات موضوعية: structure, function, pain, osteoarthritis, severity, outcome measure, Medicin och hälsovetenskap, Klinisk medicin, Reumatologi och inflammation, Medical and Health Sciences, Clinical Medicine, Rheumatology and Autoimmunity

الوصف: Objective. Time to theoretical indication of joint replacement surgery has been proposed as a primary outcome for potential structure-modifying interventions for osteoarthritis (OA). The objectives of this OMERACT/OARSI Working Group were to identify pain, physical function, and structure states that represent the progression from early to late disease for individuals with OA of the hip and knee, and to create a composite measure of these 3 domains to define states of OA severity and a surrogate measure of "need for joint replacement surgery." Methods. For pain, focus groups and one-on-one interviews were used. For function, Rasch analysis was performed on existing indices - the Hip Dysfunction and Osteoarthritis Outcome Score (HOOS) and the Knee injury and Osteoarthritis Outcome Score (KOOS), each of which subsumes the Western Ontario and McMaster University Osteoarthritis Index (WOMAC) questions. For structure, a comparison of existing indices (Kellgren-Lawrence, OARSI stages, and joint space width) was performed for the hip and the knee. Results. For pain, key features of pain that are most distressing to people with OA from early to late disease were identified. For function, the reduction of the number of items based on the existing indices continues. For structure, the analysis is also ongoing. Conclusion. Preliminary results were presented at OMERACT 8; the final objective will be to combine the 3 domains (pain, function, and structure) and to create a composite index that could define states of severity and "need for total joint replacement," which could be used to evaluate treatment response to disease-modifying drugs in OA clinical trials.

الوصول الحر: https://lup.lub.lu.se/record/650760Test
http://www.jrheum.com/subscribers/07/06/1432.htmlTest

المؤلفون: Klara, Kristina, Collins, Jamie E., Gurary, Ellen, Elman, Scott A., Stenquist, Derek S., Losina, Elena, Katz, Jeffrey N.

المصدر: Journal of Rheumatology; Jul2016, Vol. 43 Issue 7, p1421-1426, 6p

المؤلفون: Gossec, Laure, Paternotte, Simon, Bingham III, Clifton O., Clegg, Daniel O., Coste, Philippe, Conaghan, Philip G., Davis, Aileen M., Giacovelli, Giampaolo, Gunther, Klaus-Peter, Hawker, Gillian, Hochberg, Marc C., Jordan, Joanne M., Katz, Jeffrey N., Kloppenburg, Margreet, Lanzarotti, Arturo, Lim, Keith, Lohmander, L. Stefan, Mahomed, Nizar N., Maillefert, Jean Francis, Manno, Rebecca L.

المصدر: Journal of Rheumatology; Aug2011, Vol. 38 Issue 8, p1765-1769, 5p

المؤلفون: Cadarette SM, Katz JN, Brookhart MA, Levin R, Stedman MR, Choudhry NK, Solomon DH, Cadarette, Suzanne M, Katz, Jeffrey N, Brookhart, M Alan, Levin, Raisa, Stedman, Margaret R, Choudhry, Niteesh K, Solomon, Daniel H

المصدر: Journal of Rheumatology; Feb2008, Vol. 35 Issue 2, p319-326, 8p

المؤلفون: Lübbeke A, Katz JN, Perneger TV, Hoffmeyer P, Lübbeke, Anne, Katz, Jeffrey N, Perneger, Thomas V, Hoffmeyer, Pierre

المصدر: Journal of Rheumatology; Feb2007, Vol. 34 Issue 2, p394-400, 7p

المؤلفون: Mahomed, Nizar N, Liang, Matthew H, Cook, Earl F, Daltroy, Lawren H, Fortin, Paul R, Fossel, Anne H, Katz, Jeffrey N

المصدر: Journal of Rheumatology; June 2002, Vol. 29 Issue: 6 p1273-1279, 7p

مستخلص: OBJECTIVE: To evaluate the relationship between patient expectations of total joint arthroplasty (TJA) and health related quality of life plus satisfaction 6 months after surgery. Methods. This prospective cohort study included patients undergoing primary total hip (THA) and knee arthroplasty (TKA). Patients were evaluated with self-report questionnaires prior to surgery and 6 months post-surgery. Medical Outcomes Study Short Form 36 (SF-36), the Western Ontario McMaster Universities Osteoarthritis Index (WOMAC), and a satisfaction scale were used to evaluate outcomes at final followup. Multivariate regression models were used to evaluate the impact of expectations on outcomes. RESULTS: There were 102 patients with THA and 89 with TKA. Mean age was 66 years. All patients achieved significant improvements in their WOMAC and SF-36 scores following surgery. Patient expectations regarding surgery were not associated with their age, gender, index joint of surgery, marital status, or race. Expectations were not correlated with pre-operative functional health status. Expectation of complete pain relief after surgery was an independent predictor of better physical function and improvement in level of pain at 6 months post-surgery. Expectation of low risk of complications from TJA was an independent predictor of greater satisfaction. CONCLUSIONS: Patient expectations were important independent predictors of improved functional outcomes and satisfaction following TJA. Greater understanding of the relationship between expectations and outcomes may improve the process of care and outcomes of TJA.

المؤلفون: Solomon, Daniel H, Katz, Jeffrey N

المصدر: Journal of Rheumatology; July 2002, Vol. 29 Issue: 7 p1345-1347, 3p