المؤلفون: John F. Carpenter, Cheng Her

المصدر: Journal of Pharmaceutical Sciences. 109:739-749

مصطلحات موضوعية: Materials science, Chemical substance, Light, Drug Compounding, Polysorbates, Pharmaceutical Science, Nanoparticle tracking analysis, Nanoparticle, 02 engineering and technology, Buffers, 030226 pharmacology & pharmacy, Polyvinyl alcohol, Excipients, Protein Aggregates, 03 medical and health sciences, chemistry.chemical_compound, Colloid, 0302 clinical medicine, Nanotechnology, Colloids, Particle Size, Microparticle, Infusions, Intravenous, Infusion Pumps, Immunoglobulins, Intravenous, Equipment Design, Hydrogen-Ion Concentration, 021001 nanoscience & nanotechnology, chemistry, Nanoparticles, Particle, Stress, Mechanical, Particle size, 0210 nano-technology, Biomedical engineering

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1647ce370bf5b7365a09d33157a3b83dTest
https://doi.org/10.1016/j.xphs.2019.05.013Test

المؤلفون: Akira Shiota, Takashi Tadokoro, Hiroaki Oyama, Hiroki Koga, Katsumi Maenaka, Masanori Noda, Susumu Uchiyama, Tetsuo Torisu, Masami Yokoyama

المصدر: Journal of Pharmaceutical Sciences. 109:308-315

مصطلحات موضوعية: Sodium Acetate, Protein Conformation, Drug Compounding, Sodium, Pharmaceutical Science, chemistry.chemical_element, 02 engineering and technology, Buffers, 030226 pharmacology & pharmacy, Mass Spectrometry, Buffer (optical fiber), Protein Aggregates, 03 medical and health sciences, chemistry.chemical_compound, Colloid, 0302 clinical medicine, Computational chemistry, Sodium citrate, Protein Unfolding, Calorimetry, Differential Scanning, Protein Stability, Temperature, Antibodies, Monoclonal, Hydrogen-Ion Concentration, 021001 nanoscience & nanotechnology, Monomer, Models, Chemical, chemistry, Virial coefficient, Immunoglobulin G, Chromatography, Gel, 0210 nano-technology, Nonlinear regression, Sodium acetate

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb19ee6c4fb43cdd23dea5c146095bc9Test
https://doi.org/10.1016/j.xphs.2019.10.038Test

المؤلفون: Marisa K. Joubert, Nathan H. Joh, Linda O. Narhi, Gregory V. Barnett, Nancy Jiao, Twinkle R. Christian, Shawn Cao

المصدر: Journal of Pharmaceutical Sciences. 109:640-645

مصطلحات موضوعية: Drug Compounding, Polysorbates, Pharmaceutical Science, 02 engineering and technology, Buffers, Protein aggregation, 030226 pharmacology & pharmacy, Flow imaging, Protein Aggregates, Surface-Active Agents, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Drug Stability, Pulmonary surfactant, Silicone Oils, Protein particles, Particle Size, Drug Packaging, Polysorbate, Chromatography, Protein Stability, Syringes, Drop (liquid), Antibodies, Monoclonal, Hydrogen-Ion Concentration, 021001 nanoscience & nanotechnology, Silicone oil, chemistry, Immunoglobulin G, Proteolysis, Stress, Mechanical, Particle size, 0210 nano-technology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10ca4a3ed083de2b8d99ffde5e740978Test
https://doi.org/10.1016/j.xphs.2019.10.066Test

المؤلفون: Robert D. Sitrin, Lakshmi Khandke, David B. Volkin, David McAdams, John M. Hickey, Jessica A. White, Sangeeta B. Joshi, Sanjeev Agarwal, Stanley J. Cryz

المصدر: Journal of Pharmaceutical Sciences

مصطلحات موضوعية: Preservative, Protein Conformation, medicine.medical_treatment, Drug Compounding, Pharmaceutical Science, formulation, Aluminum Hydroxide, 02 engineering and technology, Buffers, 030226 pharmacology & pharmacy, Article, law.invention, 03 medical and health sciences, Viral Proteins, 0302 clinical medicine, Antigen, adjuvant, Adjuvants, Immunologic, Drug Stability, law, vaccine, preservative, medicine, Deamidation, Antigens, Viral, Gel electrophoresis, Vaccines, Synthetic, Chromatography, Chemistry, Protein Stability, Thimerosal, Preservatives, Pharmaceutical, Rotavirus Vaccines, Temperature, stability, Hydrogen-Ion Concentration, 021001 nanoscience & nanotechnology, Fusion protein, rotavirus, Vaccines, Subunit, Recombinant DNA, 0210 nano-technology, Adjuvant

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7058458b69fb8775360763a94ee10085Test
http://europepmc.org/articles/PMC6941222Test

المؤلفون: Lihua Huang, Steven J. Thomas, Tingting Wang, Natarajan Rajagopalan, Ning Wang, Matthew Clemens, Markham Aaron Paul

المصدر: Journal of Pharmaceutical Sciences. 108:1264-1271

مصطلحات موضوعية: Surface Properties, Chemistry, Pharmaceutical, Oxide, Pharmaceutical Science, Excipient, Poloxamer, 02 engineering and technology, Buffers, 030226 pharmacology & pharmacy, Excipients, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Ultraviolet visible spectroscopy, Drug Stability, Liquid chromatography–mass spectrometry, medicine, Histidine, Chemistry, Hydrogen-Ion Concentration, 021001 nanoscience & nanotechnology, Chemical engineering, Drug delivery, Degradation (geology), Chemical stability, 0210 nano-technology, Hydrophobic and Hydrophilic Interactions, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25a635a8129c1a1552aff1f8098807faTest
https://doi.org/10.1016/j.xphs.2018.10.057Test

المؤلفون: Haley Bacon, Jeff Abel, Andrew Kosky, Rahul Kaushik, Gerd R. Kleemann, Ball Nicole

المصدر: Journal of Pharmaceutical Sciences. 107:1296-1303

مصطلحات موضوعية: 0106 biological sciences, 0301 basic medicine, Drug Compounding, Static Electricity, Ultrafiltration, Pharmaceutical Science, Excipient, Acetates, Buffers, 01 natural sciences, Buffer (optical fiber), Diffusion, Excipients, 03 medical and health sciences, 010608 biotechnology, Protein purification, medicine, Chromatography, High Pressure Liquid, Mathematics, Chromatography, Scale (chemistry), Antibodies, Monoclonal, Hydrogen-Ion Concentration, Standard curve, Diafiltration, 030104 developmental biology, Models, Chemical, Volume (thermodynamics), medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf33286c863fd8afcb305bb1ac040200Test
https://doi.org/10.1016/j.xphs.2018.01.010Test

المؤلفون: Alina Kulakova, Gerhard Winter, Matja Zalar, Alexander P. Golovanov, Hristo L. Svilenov, Pernille Harris

المصدر: Svilenov, H L, Kulakova, A, Zalar, M, Golovanov, A P, Harris, P & Winter, G 2020, ' Orthogonal techniques to study the effect of pH, sucrose and arginine salts on monoclonal antibody physical stability and aggregation during long-term storage ', Journal of Pharmaceutical Sciences, vol. 109, no. 1, pp. 584-594 . https://doi.org/10.1016/j.xphs.2019.10.065Test
Journal of pharmaceutical sciences 109(1), 584-594 (2020). doi:10.1016/j.xphs.2019.10.065
Journal of pharmaceutical sciences S0022354919307373 (2019). doi:10.1016/j.xphs.2019.10.065
Svilenov, H L, Kulakova, A, Zalar, M, Golovanov, A P, Harris, P & Winter, G 2020, ' Orthogonal Techniques to Study the Effect of pH, Sucrose, and Arginine Salts on Monoclonal Antibody Physical Stability and Aggregation During Long-Term Storage ', Journal of Pharmaceutical Sciences, vol. 109, no. 1, pp. 584-594 . https://doi.org/10.1016/j.xphs.2019.10.065Test
Journal of Pharmaceutical Sciences

مصطلحات موضوعية: Sucrose, Time Factors, Arginine, Drug Compounding, Drug Storage, Pharmaceutical Science, 02 engineering and technology, Protein aggregation, Buffers, 030226 pharmacology & pharmacy, 03 medical and health sciences, chemistry.chemical_compound, Protein Aggregates, 0302 clinical medicine, Drug Stability, Protein formulation, Thermal stability, ddc:610, Colloids, Monoclonal antibody(s), Fluorescence spectroscopy, Protein Unfolding, Physical stability, pH, Protein Stability, Arginine glutamate, Temperature, Antibodies, Monoclonal, Dipeptides, Hydrogen-Ion Concentration, 021001 nanoscience & nanotechnology, Nuclear magnetic resonance (NMR) spectroscopy, 3. Good health, High-Throughput Screening Assays, Monomer, chemistry, Ionic strength, Yield (chemistry), Biophysics, Urea, 0210 nano-technology, Light scattering (dynamic)

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fd81c5795a2e2e2230e1ccbfe6fbe8dTest
https://pubmed.ncbi.nlm.nih.gov/31689429Test

المؤلفون: Andreas Niederquell, Martin Kuentz

المصدر: Journal of Pharmaceutical Sciences. 107:503-506

مصطلحات موضوعية: Taurocholic Acid, Drug, food.ingredient, Chemical structure, media_common.quotation_subject, Pharmaceutical Science, 02 engineering and technology, Buffers, Free-energy relationship, 030226 pharmacology & pharmacy, Lecithin, Micelle, 03 medical and health sciences, Colloid, 0302 clinical medicine, food, Computational chemistry, Lecithins, Organic chemistry, Intestinal Mucosa, Solubility, media_common, Chemistry, Solvation, Fasting, Hydrogen-Ion Concentration, 021001 nanoscience & nanotechnology, Body Fluids, Intestinal Absorption, Pharmaceutical Preparations, 0210 nano-technology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b89957de5c8736882e654a61cc497686Test
https://doi.org/10.1016/j.xphs.2017.08.017Test

المؤلفون: Khadijah Edueng, Claudia da Costa Mathews, Rikesh Dattani, Caroline Alvebratt, Anette Müllertz, Krista Ojala, Peter Sieger, Sara B. E. Andersson, Yan He, Jan Bevernage, Damien Bonneau, Thomas Müller, Uwe Muenster, Cecilie Maria Madsen, René Holm, Christel A. S. Bergström, Thomas Rades

المصدر: Journal of Pharmaceutical Sciences. 105:2864-2872

مصطلحات موضوعية: Chemistry, Pharmaceutical, Pharmaceutical Science, 02 engineering and technology, Buffers, 030226 pharmacology & pharmacy, Intestinal fluid, 03 medical and health sciences, 0302 clinical medicine, X-Ray Diffraction, Solubility, Dissolution, Chromatography, High Pressure Liquid, Detection limit, Chromatography, Chemistry, Phosphate buffered saline, Reproducibility of Results, Hydrogen-Ion Concentration, 021001 nanoscience & nanotechnology, Body Fluids, Kinetics, Water soluble, Powders, 0210 nano-technology, Algorithms

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16d4048dd450d91e236294690bf4ee99Test
https://doi.org/10.1016/j.xphs.2016.03.010Test

المؤلفون: Christopher J. Roberts, Bruce A. Kerwin, Gregory V. Barnett, Alexander Hillsley, Vladimir I. Razinkov

المصدر: Journal of Pharmaceutical Sciences. 105:1066-1073

مصطلحات موضوعية: 0301 basic medicine, Chemistry, Pharmaceutical, Analytical chemistry, Pharmaceutical Science, Activation energy, Acetates, Buffers, Protein aggregation, 030226 pharmacology & pharmacy, Citric Acid, Isothermal process, Ion, Excipients, Protein Aggregates, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Differential scanning calorimetry, Static light scattering, Protein Unfolding, Ions, Chemistry, Temperature, Antibodies, Monoclonal, Hydrogen-Ion Concentration, 030104 developmental biology, Biochemistry, Immunoglobulin G, Degradation (geology), Streptavidin, Sodium acetate

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fd4cdde67d3221e433b925a51dda99bTest
https://doi.org/10.1016/j.xphs.2015.12.017Test