A Pilot Study of Neural Correlates of Loss of Control Eating in Children With Overweight/Obesity: Probing Intermittent Access to Food as a Means of Eliciting Disinhibited Eating
| العنوان: | A Pilot Study of Neural Correlates of Loss of Control Eating in Children With Overweight/Obesity: Probing Intermittent Access to Food as a Means of Eliciting Disinhibited Eating |
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| المؤلفون: | Sarah K. Keedy, K. Luan Phan, Daniel P. Dickstein, Andrea B. Goldschmidt, Setareh O'Brien, Daniel Le Grange, Jennifer O. Fisher, Annmarie MacNamara |
| المصدر: | Journal of pediatric psychology, vol 43, iss 8 |
| بيانات النشر: | Oxford University Press (OUP), 2018. |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | Male, Pediatric Obesity, 050103 clinical psychology, Food intake, Child Behavior, Pilot Projects, Audiology, Overweight, 0302 clinical medicine, Original Research Articles, Developmental and Educational Psychology, Psychology, Child, medicine.diagnostic_test, digestive, oral, and skin physiology, 05 social sciences, Unconsciousness, Brain, Magnetic Resonance Imaging, neural activation, loss of control eating, Female, medicine.symptom, executive functioning, medicine.medical_specialty, Neuroimaging, Developmental & Child Psychology, Basic Behavioral and Social Science, Feeding and Eating Disorders, 03 medical and health sciences, Reward, Clinical Research, Behavioral and Social Science, medicine, Humans, 0501 psychology and cognitive sciences, Obesity, Nutrition, Neural correlates of consciousness, business.industry, Overweight obesity, Neurosciences, dietary restriction, Feeding Behavior, medicine.disease, Food, disinhibited eating, Pediatrics, Perinatology and Child Health, business, Functional magnetic resonance imaging, 030217 neurology & neurosurgery |
| الوصف: | Objective Neural substrates of loss of control (LOC) eating are undercharacterized. We aimed to model intermittent access to food to elicit disinhibited eating in youth undergoing neuroimaging, given evidence that restricted food access may increase subsequent food intake via enhancing reward value of food and diminishing eating-related self-control. Methods Participants were 18 preadolescents (aged 9-12 years) who were overweight/obese with recent LOC eating (OW-LOC; n = 6); overweight/obese with no history of LOC eating (OW-CON; n = 5); or non-overweight with no history of LOC eating (NW-CON; n = 7). Participants underwent functional magnetic resonance imaging during a simulated food restriction paradigm in which they were alternately given restricted or unrestricted access to milkshake solutions. Results There were no significant main effects of restricted versus unrestricted access to milkshake flavors. Group main effects revealed increased activation for OW-LOC relative to OW-CON in areas related to attentional processes (right middle frontal gyrus), inhibitory control/attentional shifts (right and left cuneus), and emotion regulation (left cingulate gyrus); and for OW-LOC relative to NW-CON in areas related to response inhibition (right inferior frontal gyrus). Significant block type × group interaction effects were found for the right middle frontal gyrus, left cingulate gyrus, and left cuneus, but these appeared to be accounted for primarily by group. Discussion There were clear group differences in neural activity in brain regions related to self-regulation during a food restriction paradigm. Elevations in these regions among OW-LOC relative to OW-CON and NW-CON, respectively, may suggest that youth with LOC eating expended more cognitive effort to regulate ingestive behavior. |
| تدمد: | 1465-735X 0146-8693 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05041db82384129e081eb66fbb667c7fTest https://doi.org/10.1093/jpepsy/jsy009Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....05041db82384129e081eb66fbb667c7f |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 1465735X 01468693 |
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