Technological Advances in Deep Brain Stimulation
| العنوان: | Technological Advances in Deep Brain Stimulation |
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| المؤلفون: | Keyoumars Ashkan, Michael Samuel, Ismail Ughratdar |
| المصدر: | Journal of Parkinson's Disease. 5:483-496 |
| بيانات النشر: | IOS Press, 2015. |
| سنة النشر: | 2015 |
| مصطلحات موضوعية: | Clinical Trials as Topic, Neuronavigation, Deep brain stimulation, Computer science, business.industry, Deep Brain Stimulation, medicine.medical_treatment, Brain, Parkinson Disease, Lead location, Neuromodulation (medicine), Cellular and Molecular Neuroscience, Software, Human–computer interaction, medicine, Humans, Robot, Software design, Neurology (clinical), business, Electrodes, Electromagnetic Phenomena, Stereotactic neurosurgery |
| الوصف: | Functional and stereotactic neurosurgery has always been regarded as a subspecialty based on and driven by technological advances. However until recently, the fundamentals of deep brain stimulation (DBS) hardware and software design had largely remained stagnant since its inception almost three decades ago. Recent improved understanding of disease processes in movement disorders as well clinician and patient demands has resulted in new avenues of development for DBS technology. This review describes new advances both related to hardware and software for neuromodulation. New electrode designs with segmented contacts now enable sophisticated shaping and sculpting of the field of stimulation, potentially allowing multi-target stimulation and avoidance of side effects. To avoid lengthy programming sessions utilising multiple lead contacts, new user-friendly software allows for computational modelling and individualised directed programming. Therapy delivery is being improved with the next generation of smaller profile, longer-lasting, re-chargeable implantable pulse generators (IPGs). These include IPGs capable of delivering constant current stimulation or personalised closed-loop adaptive stimulation. Post-implantation Magnetic Resonance Imaging (MRI) has long been an issue which has been partially overcome with 'MRI conditional devices' and has enabled verification of DBS lead location. Surgical technique is considering a shift from frame-based to frameless stereotaxy or greater role for robot assisted implantation. The challenge for these contemporary techniques however, will be in demonstrating equivalent safety and accuracy to conventional methods. We also discuss potential future direction utilising wireless technology allowing for miniaturisation of hardware. |
| تدمد: | 1877-718X 1877-7171 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2470ca8a16392bbca21cb6ddbc7f2941Test https://doi.org/10.3233/jpd-150579Test |
| رقم الانضمام: | edsair.doi.dedup.....2470ca8a16392bbca21cb6ddbc7f2941 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 1877718X 18777171 |
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