Effect of Genetic-Environmental Interaction on Chinese Childhood Myopia
| العنوان: | Effect of Genetic-Environmental Interaction on Chinese Childhood Myopia |
|---|---|
| المؤلفون: | Jie Yang, Yao Xiang, Yan Wang, Chen-Wei Pan, Fengyun Zhang, Wenyi Yang, Xiyan Zhang |
| المصدر: | Journal of Ophthalmology, Vol 2020 (2020) Journal of Ophthalmology |
| بيانات النشر: | Hindawi Limited, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Article Subject, genetic structures, business.industry, Regression analysis, RE1-994, 010502 geochemistry & geophysics, 01 natural sciences, eye diseases, 03 medical and health sciences, Ophthalmology, 0302 clinical medicine, Relative risk, 030221 ophthalmology & optometry, Medicine, sense organs, business, Research Article, 0105 earth and related environmental sciences, Demography |
| الوصف: | Objective. The purpose of this study was to evaluate the effect of genetic-environmental interaction on myopia in Chinese children aged 6 to 9 years. Methods. Students had the physical examination and were required to provide basic demographic information. Their families were asked to fill in a questionnaire concerning factors related to myopia. Multiple regression analysis was performed, and adjusted risk ratio values were calculated to assess the role between gene and environment. Value of the environmental and genetic index (EGI) was calculated to demonstrate the effect of genetic-environmental interaction on myopia. Results. The prevalence of myopia maintained at a high level. EGI was calculated as 0.125 suggesting that genetic factors may play the 12.5% role in the formation of myopia and environmental factors may play a role of 87.5% in the formation of myopia. Conclusions. For young pupils aged 6 to 9 years, myopia prevalence maintained at a high level, and duration of homework time and staring at electronic screen were the strongest factors associated with myopia. The calculated value of EGI was low, which suggests that environmental factors may play the leading role in the formation of myopia. A long-term follow-up research to improve the accuracy value of EGI is our next job. |
| وصف الملف: | text/xhtml |
| اللغة: | English |
| تدمد: | 2090-0058 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73f9bbe0c6da8015aca18c5dc193d29dTest https://doaj.org/article/9e7cfdae2d224f7c9e1485ab696b9a41Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....73f9bbe0c6da8015aca18c5dc193d29d |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20900058 |
|---|