التفاصيل البيبلوغرافية
| العنوان: |
Cervical length and cervicovaginal HCG for prediction of pre-term birth in women with signs and symptoms of pre-term labour. |
| المؤلفون: |
Bagga, R.1 (AUTHOR), Takhtani, M.1 (AUTHOR), Suri, V.1 (AUTHOR), Adhikari, K.1 (AUTHOR) drkp1981@gmail.com, Arora, S.2 (AUTHOR), Bhardwaj, S.2 (AUTHOR) |
| المصدر: |
Journal of Obstetrics & Gynaecology. Jul2010, Vol. 30 Issue 5, p451-455. 5p. 5 Charts, 1 Graph. |
| مصطلحات موضوعية: |
*PREMATURE labor, *PREGNANCY, *TRANSVAGINAL ultrasonography, *DELIVERY (Obstetrics), *CHILDBIRTH, *BIOMARKERS |
| مستخلص: |
The study group consisted of 100 women with a singleton pregnancy with pre-term labour between 26-36 weeks' gestation. Cervicovaginal secretions were collected for HCG assay and cervical length was measured by transvaginal sonography (TVS). These parameters were analysed to predict pre-term birth. The pre-term delivery rate was 55%; 24% delivered within 48 h and 11% within 7 days of admission. The sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of cervical length or=45 mIU/ml was the optimal cut-off, with a sensitivity, specificity, PPV and NPV for predicting delivery within 48 h and 7 days to be 95.8%, 73.7%, 53.5% and 98.2% and 85.7%, 80%, 69.8% and 91.2%, respectively. Combining either qualitative or quantitative HCG assay with cervical length significantly increased the sensitivity and NPV of cervical length alone for prediction of pre-term delivery both within 48 h and 7 days. It was concluded that increased cervicovaginal HCG and reduced cervical length predicted an increased risk of pre-term delivery in women with pre-term labour. Qualitative cervicovaginal HCG assay may be used as a bedside test to predict pre-term delivery within 48 h or within 7 days. [ABSTRACT FROM AUTHOR] |
| قاعدة البيانات: |
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