OpenDose: open access resources for nuclear medicine dosimetry
| العنوان: | OpenDose: open access resources for nuclear medicine dosimetry |
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| المؤلفون: | David Sarrut, A. Desbrée, Gilles Mathieu, Manuel Bardiès, Jérémie Dabin, Pawel Bzowski, Francesca Botta, Maxime Chauvin, Alessandra Malaroda, Alex Vergara Gil, Lara Struelens, A P Robinson, Erin McKay, Erick Mora-Ramirez, Damian Borys, Nadia Falzone, Andrea Mairani, Ana M. Denis-Bacelar, B.Q. Lee |
| المساهمون: | Centre de Recherches en Cancérologie de Toulouse (CRCT), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Silesian University of Technology, European Institute of Oncology [Milan] (ESMO), Centre d'Etude de l'Energie Nucléaire (SCK-CEN), National Physical Laboratory [Teddington] (NPL), Institut de Radioprotection et de Sûreté Nucléaire, Fontenay-aux-Roses, University of Oxford [Oxford], Heidelberg University Hospital [Heidelberg], University of Wollongong [Australia], Institut National de la Santé et de la Recherche Médicale (INSERM), St George Hospital, Centre de Recherche en Acquisition et Traitement de l'Image pour la Santé (CREATIS), Université Jean Monnet [Saint-Étienne] (UJM)-Hospices Civils de Lyon (HCL)-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Université de Lyon-Institut National des Sciences Appliquées (INSA)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM), Chauvin, Maxime, Institut de Radioprotection et de Sûreté Nucléaire (IRSN), University of Oxford, Imagerie Tomographique et Radiothérapie, Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Hospices Civils de Lyon (HCL)-Université Jean Monnet - Saint-Étienne (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Hospices Civils de Lyon (HCL)-Université Jean Monnet - Saint-Étienne (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS) |
| المصدر: | Journal of Nuclear Medicine Journal of Nuclear Medicine, Society of Nuclear Medicine, 2020, pp.jnumed.119.240366. ⟨10.2967/jnumed.119.240366⟩ J Nucl Med Journal of Nuclear Medicine, 2020, pp.jnumed.119.240366. ⟨10.2967/jnumed.119.240366⟩ |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Radiation Dosimetry, open-access database, Relational database, Computer science, International Cooperation, Monte Carlo method, [SDV.CAN]Life Sciences [q-bio]/Cancer, 030218 nuclear medicine & medical imaging, Access to Information, 03 medical and health sciences, 0302 clinical medicine, Resource (project management), Software, [SDV.CAN] Life Sciences [q-bio]/Cancer, Radiation Physics, Humans, Dosimetry, Radiology, Nuclear Medicine and imaging, Radiometry, Reference model, dosimetry, business.industry, Radionuclide Therapy, Monte Carlo methods, 3. Good health, Computer engineering, 030220 oncology & carcinogenesis, Absorbed dose, Educational resources, Nuclear Medicine, business, Monte Carlo Method, Radiobiology/Dosimetry |
| الوصف: | Radiopharmaceutical dosimetry depends on the localization in space and time of radioactive sources and requires the estimation of the amount of energy emitted by the sources deposited within targets. In particular, when computing resources are not accessible, this task can be performed using precomputed tables of specific absorbed fractions (SAFs) or S values based on dosimetric models. The aim of the OpenDose collaboration is to generate and make freely available a range of dosimetric data and tools. Methods: OpenDose brings together resources and expertise from 18 international teams to produce and compare traceable dosimetric data using 6 of the most popular Monte Carlo codes in radiation transport (EGSnrc/EGS++, FLUKA, GATE, Geant4, MCNP/MCNPX, and PENELOPE). SAFs are uploaded, together with their associated statistical uncertainties, in a relational database. S values are then calculated from monoenergetic SAFs on the basis of the radioisotope decay data presented in International Commission on Radiological Protection Publication 107. Results: The OpenDose collaboration produced SAFs for all source region and target combinations of the 2 International Commission on Radiological Protection Publication 110 adult reference models. SAFs computed from the different Monte Carlo codes were in good agreement at all energies, with SDs below individual statistical uncertainties. Calculated S values were in good agreement with OLINDA/EXM 2.0 (commercial) and IDAC-Dose 2.1 (free) software. A dedicated website (www.opendose.org) has been developed to provide easy and open access to all data. Conclusion: The OpenDose website allows the display and downloading of SAFs and the corresponding S values for 1,252 radionuclides. The OpenDose collaboration, open to new research teams, will extend data production to other dosimetric models and implement new free features, such as online dosimetric tools and patient-specific absorbed dose calculation software, together with educational resources. |
| وصف الملف: | application/pdf |
| تدمد: | 0161-5505 1535-5667 |
| DOI: | 10.2967/jnumed.119.240366 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80d87970b456d8431da695d1a52148ecTest |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....80d87970b456d8431da695d1a52148ec |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 01615505 15355667 |
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| DOI: | 10.2967/jnumed.119.240366 |