دورية أكاديمية

Anti-SARS-CoV-2 humoral and cellular responses in multiple sclerosis patients treated with anti-CD20 monoclonal antibodies.

التفاصيل البيبلوغرافية
العنوان: Anti-SARS-CoV-2 humoral and cellular responses in multiple sclerosis patients treated with anti-CD20 monoclonal antibodies.
المؤلفون: Nicolas, Philippe, Marion-Moffet, Hugo, Gossez, Morgane, Vukusic, Sandra, Monneret, Guillaume, Marignier, Romain, Venet, Fabienne
المصدر: Journal of Neurology; Jan2023, Vol. 270 Issue 1, p32-36, 5p
مصطلحات موضوعية: HUMORAL immunity, CD19 antigen, MONOCLONAL antibodies, MULTIPLE sclerosis, NEUROMYELITIS optica
مستخلص: We tested 61 anti-CD20-treated MS patients (anti-CD20 patients) and 10 healthy volunteers. Dear Sirs, Multiple sclerosis (MS) patients treated with anti-CD20 monoclonal antibodies are at higher risk of severe COVID-19 [[1]]. The repartition of immune response status was significantly different in patients with or without B-cell repletion (B-cell repletion being defined as >= 1 CD20 + B cell/mm SP 3 sp 6 months after previous anti-CD20 infusion) ( I p < i 0.0001) (Fig. [Extracted from the article]
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قاعدة البيانات: Complementary Index
الوصف
تدمد:03405354
DOI:10.1007/s00415-022-11353-y