التفاصيل البيبلوغرافية
| العنوان: |
No association of inducible nitric oxide synthase gene (NOS2A) to multiple sclerosis. |
| المؤلفون: |
Blanco, Yolanda, Yagüe, Jordi, Graus, Francesc, Saiz, Albert |
| المصدر: |
Journal of Neurology; May2003, Vol. 250 Issue 5, p598-600, 3p |
| مصطلحات موضوعية: |
NITRIC oxide, INFLAMMATORY mediators, MULTIPLE sclerosis, GENETIC polymorphisms, ETHNICITY, PATIENTS |
| مصطلحات جغرافية: |
SPAIN |
| مستخلص: |
Nitric oxide (NO) is a nonspecific inflammatory mediator that has been involved in the pathogenesis of multiple sclerosis (MS). The influence of the promoter polymorphism of inducible NO synthase gene (NOS2A) on susceptibility and outcome was studied in 140 MS Spanish patients and 147 healthy controls matched for sex, age, and ethnicity. No association was found between MS susceptibility, course or outcome of the disease, and NOS2A polymorphisms. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
