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1
المؤلفون: Tina Howard, Jie Shi, Kirsten Bell, Jon Read, Dennis Huszar, Marat Alimzhanov, Claudio Chuaqui, Lynsie Almeida, Geraldine Bebernitz, Michael Zinda, Shan Huang, Qibin Su, Stephanos Ioannidis, Mei Su, Michael Howard Block, Minwei Ye, Caroline Rivard Costa
المصدر: Journal of Medicinal Chemistry. 57:144-158
مصطلحات موضوعية: Antineoplastic Agents, Pharmacology, medicine.disease_cause, Mice, Structure-Activity Relationship, chemistry.chemical_compound, Dogs, hemic and lymphatic diseases, Drug Discovery, medicine, Animals, Humans, Imidazole, Structure–activity relationship, Transferase, Protein Kinase Inhibitors, Mutation, Janus kinase 2, biology, Drug discovery, Imidazoles, JAK-STAT signaling pathway, Janus Kinase 2, Xenograft Model Antitumor Assays, Rats, chemistry, biology.protein, Molecular Medicine, Tumor growth inhibition
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dab13e0e0cd5b5d00f867f1419e01319Test
https://doi.org/10.1021/jm401546nTest -
2
المؤلفون: Changyuan Wang, Xiaodong Ma, Xiaohong Shu, Youwen Zhou, Yang Ge, Zhendong Song, Shan-Shan Huang, Kexin Liu
المصدر: Journal of medicinal chemistry. 59(14)
مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, Lung Neoplasms, Pyridones, Antineoplastic Agents, Pharmacology, Small Molecule Libraries, 03 medical and health sciences, T790M, Mice, Structure-Activity Relationship, 0302 clinical medicine, Carcinoma, Non-Small-Cell Lung, Cell Line, Tumor, Drug Discovery, medicine, Animals, Humans, Osimertinib, Rociletinib, Epidermal growth factor receptor, Lung cancer, Protein Kinase Inhibitors, EGFR inhibitors, Cell Proliferation, biology, Dose-Response Relationship, Drug, Molecular Structure, Chemistry, Cell growth, Kinase, Neoplasms, Experimental, medicine.disease, respiratory tract diseases, ErbB Receptors, 030104 developmental biology, 030220 oncology & carcinogenesis, biology.protein, Molecular Medicine, Drug Screening Assays, Antitumor
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f7b2a67fa75fd5dd3d6c332e6d41d08Test
https://pubmed.ncbi.nlm.nih.gov/26882288Test -
3
المؤلفون: Mingshi Dai, Swanee Jacutin-Porte, Wei Yin, Charles A. Minor, Shan Huang, Tracy J. Jenkins, Weirong Chen, Gang Li, Thomas E. Lightburn, Daniel Cardillo, Matthew Jones, Shomir Ghosh, Douglas F. Burdi, Christopher Blackburn, Robert Bennett, Roland Kolbeck, Sean Smith, B. Scott Freeze, Timothy D. Ocain, Geraldine C Harriman, Kenneth M. Gigstad, Bing Guan
المصدر: Journal of Medicinal Chemistry. 50:566-584
مصطلحات موضوعية: medicine.drug_class, Stereochemistry, Administration, Oral, Biological Availability, Stereoisomerism, Carboxamide, Naphthalenes, Chemical synthesis, Receptors, CCR8, Cell Line, Structure-Activity Relationship, chemistry.chemical_compound, Cricetulus, Cricetinae, Drug Discovery, medicine, Animals, Humans, Structure–activity relationship, Naphthalene, chemistry.chemical_classification, Sulfonamides, Bicyclic molecule, Biological Transport, In vitro, Rats, Sulfonamide, Solubility, chemistry, Drug Design, Molecular Medicine, Calcium, Receptors, Chemokine
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81ece8a43fb824560f99d9d32c158515Test
https://doi.org/10.1021/jm061118eTest -
4
المؤلفون: Hsu Shan Huang, Chia Chung Lee, Tsung Chih Chen, Fei Lan Liu, Ahmed Atef Ahmed Ali, Deh-Ming Chang, Chun Liang Chen, Huey-Kang Sytwu
المصدر: Journal of medicinal chemistry. 57(19)
مصطلحات موضوعية: musculoskeletal diseases, Stereochemistry, Osteoclasts, Inhibitory postsynaptic potential, Salicylanilides, Bone resorption, chemistry.chemical_compound, Mice, Structure-Activity Relationship, Osteoclast, Drug Discovery, Oxazines, medicine, Animals, Bone Resorption, Cytotoxicity, Cells, Cultured, Tartrate-resistant acid phosphatase, Chemistry, RANK Ligand, Osteoblast, Cell Differentiation, Salicylanilide, medicine.anatomical_structure, Cancer research, Molecular Medicine
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9342cc44ff8d802ae43995771e61afbcTest
https://pubmed.ncbi.nlm.nih.gov/25200306Test -
5
المؤلفون: Klaus Müller, Wolfgang Wiegrebe, Hsu Shan Huang
المصدر: Journal of Medicinal Chemistry. 39:3132-3138
مصطلحات موضوعية: Keratinocytes, Neutrophils, Leukotriene B4, Stereochemistry, Thio, Antioxidants, Lipid peroxidation, Mice, chemistry.chemical_compound, Hydroxyeicosatetraenoic Acids, Drug Discovery, medicine, Animals, Humans, Psoriasis, 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid, Lipoxygenase Inhibitors, Cells, Cultured, chemistry.chemical_classification, Molecular Structure, biology, Anthralin, HaCaT, Enzyme, medicine.anatomical_structure, chemistry, Deoxyribose, Biochemistry, Arachidonate 5-lipoxygenase, biology.protein, Molecular Medicine, Cattle, Epidermis, Keratinocyte, Cell Division
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1367996aa130881c1763c00dc98432deTest
https://doi.org/10.1021/jm960259lTest -
6
المؤلفون: Jing Wen Shih, Jen Yi Wang, Yu Cheng Lu, Jeng Fong Chiou, Hsu Shan Huang, Yen Ru Pan, Ching Cheng Hou, Jing-Jer Lin, Yaou Fong
المصدر: Journal of medicinal chemistry. 46(15)
مصطلحات موضوعية: Telomerase, Chemistry, Somatic cell, Cell Survival, Biological activity, Anthraquinones, Antineoplastic Agents, Alkaline Phosphatase, Telomere, Cell Line, DNA-Binding Proteins, Enzyme Activation, Structure-Activity Relationship, Biochemistry, Cell culture, Drug Discovery, Tumor Cells, Cultured, Molecular Medicine, Alkaline phosphatase, Humans, Telomerase reverse transcriptase, Stem cell, Drug Screening Assays, Antitumor, Enzyme Inhibitors
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1197d7496b36975e748b10835cc14e8Test
https://pubmed.ncbi.nlm.nih.gov/12852760Test -
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المؤلفون: Hsu Shan Huang, Klaus Müller, Helge Prinz, Ingo Gawlik, Klaus Ziereis
المصدر: Journal of medicinal chemistry. 40(23)
مصطلحات موضوعية: Keratinocytes, Stereochemistry, Leukotriene B4, Administration, Topical, Anti-Inflammatory Agents, Chemical synthesis, Sensitivity and Specificity, Antioxidants, chemistry.chemical_compound, Structure-Activity Relationship, Drug Discovery, Dithranol, medicine, Animals, Humans, Psoriasis, Lipoxygenase Inhibitors, Arachidonate 5-Lipoxygenase, Bicyclic molecule, Cell growth, Chemistry, Anti-Inflammatory Agents, Non-Steroidal, Anthralin, Oxidants, Quinone, medicine.anatomical_structure, Mechanism of action, Biochemistry, Leukocytes, Mononuclear, Molecular Medicine, Cattle, medicine.symptom, Keratinocyte, Cell Division, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53ceef48d305d6e5cf9047dd7f8bc872Test
https://pubmed.ncbi.nlm.nih.gov/9371243Test -
8دورية أكاديمية
المؤلفون: Tracy J. Jenkins, Bing Guan, Mingshi Dai, Gang Li, Thomas E. Lightburn, Shan Huang, B. Scott Freeze, Douglas F. Burdi, Swanee Jacutin-Porte, Robert Bennett, Weirong Chen, Charles Minor, Shomir Ghosh, Christopher Blackburn, Kenneth M. Gigstad, Matthew Jones, Roland Kolbeck, Wei Yin, Sean Smith, Daniel Cardillo
المصدر: Journal of Medicinal Chemistry; Feb2007, Vol. 50 Issue 3, p566-584, 19p
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9
المؤلفون: Paul L. Chello, James C. Parham, Lily Yip, Bao-Shan Huang
المصدر: Journal of Medicinal Chemistry. 23:575-577
مصطلحات موضوعية: Purine, Hypoxanthine Phosphoribosyltransferase, Xanthine Oxidase, Guanine, Chemical Phenomena, medicine.drug_class, Stereochemistry, Antineoplastic Agents, Carboxamide, Mice, chemistry.chemical_compound, Drug Discovery, medicine, Animals, Leukemia L1210, Xanthine oxidase, chemistry.chemical_classification, Sulfonyl, biology, Imidazoles, Aminoimidazole Carboxamide, Xanthine, Sulfonamide, Chemistry, chemistry, Xanthines, biology.protein, Molecular Medicine, Phosphoribosyltransferase
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2910af11774603a85be26f6071373da8Test
https://doi.org/10.1021/jm00179a021Test