Reactivation of overt and occult hepatitis B infection in various immunosuppressive settings
| العنوان: | Reactivation of overt and occult hepatitis B infection in various immunosuppressive settings |
|---|---|
| المؤلفون: | Caterina Sagnelli, Evangelista Sagnelli, Salvatore Guastafierro, Maria Stanzione, Messina, G. Tonziello, Mariantonietta Pisaturo, Nicolina Capoluongo, Iodice, Giuseppe Pasquale, Nicola Coppola, Marco Fiore |
| المساهمون: | Coppola, N., Tonziello, G., Pisaturo, M., Messina, V., Guastafierro, S., Fiore, M., Iodice, V., Sagnelli, C., Stanzione, M., Capoluongo, N., Pasquale, G., Sagnelli, E., Coppola, Nicola, Tonziello, G, Pisaturo, M, Messina, V, Guastafierro, Salvatore, Fiore, M, Iodice, V, Sagnelli, Caterina, Stanzione, M, Capoluongo, N, Pasquale, Giuseppe |
| المصدر: | Journal of medical virology. 83(11) |
| سنة النشر: | 2011 |
| مصطلحات موضوعية: | Occult HBV infection, Adult, Male, Antiviral Agents, Immunosuppressive disease, Immunosuppressive Agent, Antibodies, Monoclonal, Murine-Derived, Immunocompromised Host, Retrospective Studie, Virology, Telbivudine, medicine, Adefovir, Humans, Viremia, HBV infection, Aged, Retrospective Studies, Antiviral Agent, business.industry, Lamivudine, virus diseases, Entecavir, Middle Aged, Viral Load, Hepatitis B, Occult, Survival Analysis, digestive system diseases, Fludarabine, Infectious Diseases, Onco-hematological disease, DNA, Viral, Rituximab, Female, Virus Activation, Survival Analysi, business, Viral load, Immunosuppressive Agents, Vidarabine, medicine.drug, Human |
| الوصف: | The aim of the study was to evaluate clinical and virological differences in HBV reactivation between patients with overt and occult HBV infection. Twenty-three consecutive patients with symptomatic HBV reactivation occurring during or after immunosuppressive therapy were enrolled in a retrospective study: 10 with reactivation of overt HBV infection (overt group) and 13 of occult HBV infection (occult group). Twenty-one patients were treated with nucleot(s)ide analogues after HBV reactivation. Regimens including rituximab or fludarabine were administered more frequently in the occult group (61% vs. 31%, respectively). HBV reactivation was severe frequently in the overt (40%) and occult groups (38.4%). Patients in the overt group showed higher HBV-DNA titers (1.1×10 8±1.4×10 8 vs. 5.1×10 5±6.8×10 5IU; P |
| تدمد: | 1096-9071 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::012c7309d4459f46f244ebd2f6d3047eTest https://pubmed.ncbi.nlm.nih.gov/21915865Test |
| حقوق: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....012c7309d4459f46f244ebd2f6d3047e |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 10969071 |
|---|