Bone metastases from a 1p/19q codeleted and IDH1-mutant anaplastic oligodendroglioma: a case report
| العنوان: | Bone metastases from a 1p/19q codeleted and IDH1-mutant anaplastic oligodendroglioma: a case report |
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| المؤلفون: | Khalil Bourahla, Roland Schott, Georges Noël, Marie-Pierre Chenard, Mickaël Burgy |
| المصدر: | Journal of Medical Case Reports, Vol 13, Iss 1, Pp 1-5 (2019) Journal of Medical Case Reports |
| بيانات النشر: | BMC, 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | Adult, Male, Pathology, medicine.medical_specialty, IDH1, Axial skeleton, Oligodendroglioma, Brain tumor, lcsh:Medicine, Case Report, Bone Neoplasms, 030204 cardiovascular system & hematology, 03 medical and health sciences, 0302 clinical medicine, Surgical oncology, Biopsy, Medicine, Humans, Sequence Deletion, medicine.diagnostic_test, Base Sequence, business.industry, Brain Neoplasms, Bone metastases, lcsh:R, General Medicine, medicine.disease, Isocitrate Dehydrogenase, nervous system diseases, medicine.anatomical_structure, Chromosomes, Human, Pair 1, 030220 oncology & carcinogenesis, Anaplastic oligodendroglioma, Immunohistochemistry, Bone marrow, business, Metastatic oligodendroglioma |
| الوصف: | Background Oligodendroglioma is a rare type of primary brain tumor which, like other malignant gliomas, metastasizes very rarely even when in high-grade form. Case report A 36-year-old white man diagnosed 29 months previously as having 1p/19q codeleted anaplastic oligodendroglioma presented bilateral cruralgia and lower limb motor deficits. A computed tomography scan showed multiple osteoblastic bone lesions. The presence of oligodendroglial cells was revealed by bone marrow biopsy and confirmed by immunohistochemical analyses. A positon emission tomography-computed tomography scan confirmed the exclusive involvement of bones. Conclusion This case joins less than 20 other reported cases of oligodendroglioma bone marrow metastasis, and is one of only a handful of cases of diffuse bone metastases beyond the axial skeleton. To the best of our knowledge, the early relapse of 1p/19q codeleted anaplastic oligodendroglioma with this distribution of metastases has never been described in the literature. |
| اللغة: | English |
| تدمد: | 1752-1947 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb64b9a58424b927db0c0a3e2230ec3aTest http://link.springer.com/article/10.1186/s13256-019-2061-4Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....fb64b9a58424b927db0c0a3e2230ec3a |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 17521947 |
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