نتائج البحث

1

Generation and validation of a conditional knockout mouse model for desmosterolosis

المؤلفون: Roman Tyshynsky, Shailendra B. Patel, Sithara Raju Ponny, Kirthi Pulakanti, Babu Nageswararao Kanuri, Ranjuna Weerasekera, Kriya S. Patel, Vincent Fong

المصدر: Journal of Lipid Research
Journal of Lipid Research, Vol 62, Iss, Pp 100028-(2021)

مصطلحات موضوعية: 0301 basic medicine, DHCR24, 030204 cardiovascular system & hematology, Biochemistry, FDFT1, farnesyl-diphosphate farnesyl transferase 1, chemistry.chemical_compound, LDLR, low density lipoprotein receptor, 0302 clinical medicine, Endocrinology, SREBF1/2, sterol regulatory element binding transcription factor 1/2, Desmosterol, Conditional gene knockout, CYP27A1, CEACAM1, carcinoembryonic antigen-related cell adhesion molecule 1, GEO, Gene Expression Omnibus, MTTP, microsomal triglyceride transfer protein, Sterol homeostasis, dysmorphology, CYP7A1, cytochrome P450 family 7 subfamily A member 1, FAS, fatty acid synthase, animal models, liver-X-receptor, desmosterol, HMGCR, 3-hydroxy-3-methylglutaryl-CoA reductase, NR1H2/3/4, nuclear receptor subfamily 1 group H member 2/3/4, Research Article, medicine.medical_specialty, LIPC, hepatic triacylglycerol lipase, CYP8B1, cytochrome P450 family 8 subfamily B member 1, bile, QD415-436, Biology, Cholesterol 7 alpha-hydroxylase, liver, CD36, cluster of differentiation 36, CYP27A1, cytochrome P450 family 27 subfamily A member 1, Lipid Metabolism, Inborn Errors, DHCR7, 3β-hydroxysterol-Δ7 reductase, 03 medical and health sciences, Internal medicine, DHCR24, 3β-hydroxysterol-Δ24 reductase, medicine, Abnormalities, Multiple, Liver X receptor, 7-DHC, 7-dehydrocholsterol, SCARB1, Scavenger receptor class B member 1, cholesterol, Cell Biology, medicine.disease, SCARB1, Desmosterolosis, lipoproteins, 030104 developmental biology, chemistry, gene expression, LXR, liver X receptor, PCSK9, proprotein convertase subtilisin/kexin type 9

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07891d6a4a13061ce051312bb0c74109Test
http://europepmc.org/articles/PMC7933790Test

2

Robust passive and active efflux of cellular cholesterol to a designer functional mimic of high density lipoprotein

المؤلفون: Michael C. Phillips, Chad A. Mirkin, Daniel J. Rader, Duyen Quach, C. Shad Thaxton, Nicholas N. Lyssenko, Kasey C. Vickers, John S. Millar, Andrea J. Luthi, Kaylin M. McMahon

المصدر: Journal of Lipid Research
Journal of Lipid Research, Vol 56, Iss 5, Pp 972-985 (2015)

مصطلحات موضوعية: ATP-binding cassette transporter G1, Cardiotonic Agents, Lipoproteins, Phospholipid, Drug Evaluation, Preclinical, QD415-436, ATP-binding cassette transporter A1, Coronary Artery Disease, 030204 cardiovascular system & hematology, Biology, Biochemistry, Cell Line, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Endocrinology, High-density lipoprotein, Drug Stability, scavenger receptor class B type I, Cricetinae, Animals, Scavenger receptor, Research Articles, Phospholipids, 030304 developmental biology, ATP Binding Cassette Transporter, Subfamily G, Member 1, 0303 health sciences, Apolipoprotein A-I, Cholesterol, Macrophages, Molecular Mimicry, Biological Transport, Cell Biology, Scavenger Receptors, Class B, ATP Binding Cassette Transporter 1, chemistry, ABCG1, ABCA1, biology.protein, Nanoparticles, lipids (amino acids, peptides, and proteins), ATP-Binding Cassette Transporters, Efflux, Gold, atherosclerosis, cholesterol efflux

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0550abb1901911bc2d06d1f118adbb66Test
http://europepmc.org/articles/PMC4409287Test

3

Nascent HDL formation in hepatocytes and role of ABCA1, ABCG1, and SR-BI

المؤلفون: Nancy R. Webb, Maria C. de Beer, Deneys R. van der Westhuyzen, Ailing Ji, Joanne M. Wroblewski, Lei Cai

المصدر: Journal of Lipid Research, Vol 53, Iss 3, Pp 446-455 (2012)

مصطلحات موضوعية: Lipoproteins, Blotting, Western, class B scavenger receptor type 1, QD415-436, Biology, Real-Time Polymerase Chain Reaction, Biochemistry, chemistry.chemical_compound, Basal (phylogenetics), Mice, Endocrinology, Nascent HDL, Cellular cholesterol, polycyclic compounds, hepatocyte, Animals, Humans, Immunoprecipitation, high density lipoprotein formation, Liver X receptor, Research Articles, Cells, Cultured, ATP Binding Cassette Transporter, Subfamily G, Member 1, Mice, Knockout, ATP binding cassette transporter G1, Cholesterol, nutritional and metabolic diseases, Cell Biology, Scavenger Receptors, Class B, Molecular biology, chemistry, ABCG1, ABCA1, biology.protein, Hepatocytes, ATP-Binding Cassette Transporters, lipids (amino acids, peptides, and proteins), Efflux, ATP binding cassette transporter A1, Lipoproteins, HDL, cholesterol efflux, ATP Binding Cassette Transporter 1

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02f737cd53abd1e4e531bdbcfba5c063Test
http://www.sciencedirect.com/science/article/pii/S0022227520413604Test

4

ABCG1 regulates mouse adipose tissue macrophage cholesterol levels and ratio of M1 to M2 cells in obesity and caloric restriction

المؤلفون: Elizabeth J. Tarling, Renee C. LeBoeuf, Chongren Tang, Timothy S. McMillen, Hao Wei

المصدر: Journal of Lipid Research, Vol 56, Iss 12, Pp 2337-2347 (2015)

مصطلحات موضوعية: Male, medicine.medical_specialty, Adipose tissue macrophages, Lipoproteins, Sterol O-acyltransferase, Adipose tissue, QD415-436, Biology, Biochemistry, Macrophage chemotaxis, chemistry.chemical_compound, Mice, Endocrinology, Internal medicine, Adipocyte, medicine, Lipolysis, Glucose homeostasis, Animals, Obesity, Research Articles, ATP Binding Cassette Transporter, Subfamily G, Member 1, Caloric Restriction, ATP binding cassette transporter G1, diabetes, Cholesterol, Macrophages, Cell Biology, Mice, Inbred C57BL, chemistry, Adipose Tissue, lipids (amino acids, peptides, and proteins), ATP-Binding Cassette Transporters, ATP binding cassette transporter A1, fatty acid, gallstones

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e414c4d15627e36c1afb0fa6e27808c3Test
https://pubmed.ncbi.nlm.nih.gov/26489644Test

5

ATP binding cassette G1-dependent cholesterol efflux during inflammation

المؤلفون: Maria C. de Beer, Anisa Jahangiri, Ashley M. Vaughan, Nancy R. Webb, Frederick C. de Beer, Deneys R. van der Westhuyzen, Ailing Ji

المصدر: Journal of Lipid Research. 52:345-353

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e2735d87692fafa854804ece06ba557Test
https://doi.org/10.1194/jlr.m012328Test

6

Regulation of ABCG1 expression in human keratinocytes and murine epidermis

المؤلفون: Biao Lu, Peter M. Elias, Debbie Crumrine, Mao-Qiang Man, Elizabeth J. Tarling, Peggy Kim, Peter A. Edwards, Yan J. Jiang, Kenneth R. Feingold

المصدر: Journal of Lipid Research, Vol 51, Iss 11, Pp 3185-3195 (2010)

مصطلحات موضوعية: Keratinocytes, Hydrocarbons, Fluorinated, Peroxisome proliferator-activated receptor, Lamellar granule, Biochemistry, Calcitriol receptor, Gene Knockout Techniques, Mice, Endocrinology, PPAR delta, Research Articles, Barrier function, ATP Binding Cassette Transporter, Subfamily G, Member 1, Liver X Receptors, chemistry.chemical_classification, Sulfonamides, Cell Differentiation, Orphan Nuclear Receptors, Up-Regulation, Cell biology, Sterols, Female, adenosine 5′-triphosphate binding cassette transporter, lipids (amino acids, peptides, and proteins), Peroxisome proliferator-activated receptor delta, liver X receptor, medicine.medical_specialty, Lipoproteins, QD415-436, Biology, Retinoid X receptor, Permeability, Internal medicine, medicine, Animals, Humans, lamellar body, RNA, Messenger, Liver X receptor, Dose-Response Relationship, Drug, peroxisome proliferator-activated receptor, Cell Biology, Retinoic acid receptor, Epidermal Cells, Gene Expression Regulation, chemistry, ATP-Binding Cassette Transporters, Epidermis, barrier function

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b27161089ff02f006a9412ca6a44c2cdTest
https://doi.org/10.1194/jlr.m006445Test

7

Targeted PPARγ deficiency in alveolar macrophages disrupts surfactant catabolism

المؤلفون: Mary Jane Thomassen, Mani S. Kavuru, A Malur, Anna D. Baker, Anagha Malur, Shobha Ghosh, Barbara P. Barna

المصدر: Journal of Lipid Research, Vol 51, Iss 6, Pp 1325-1331 (2010)

مصطلحات موضوعية: medicine.medical_specialty, pulmonary alveolar proteinosis, Lipoproteins, Peroxisome proliferator-activated receptor, QD415-436, Biochemistry, Gene Knockout Techniques, Mice, Surface-Active Agents, Endocrinology, Internal medicine, Macrophages, Alveolar, medicine, Animals, Liver X receptor, Lung, Surfactant homeostasis, ATP Binding Cassette Transporter, Subfamily G, Member 1, Liver X Receptors, chemistry.chemical_classification, biology, Catabolism, Lipid metabolism, Cell Biology, respiratory system, Orphan Nuclear Receptors, medicine.disease, PPAR gamma, peroxisome proliferator-activated receptor-γ, Cholesterol, ABCG1, chemistry, granulocyte-macrophage colony-stimulating factor, Organ Specificity, ABCA1, Immunology, biology.protein, ATP-Binding Cassette Transporters, lipids (amino acids, peptides, and proteins), Lipoproteins, HDL, Pulmonary alveolar proteinosis, Research Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01b73a43bb382467dd5a802ec9c9c463Test
https://doi.org/10.1194/jlr.m001651Test

8

Serum, but not monocyte macrophage foam cells derived from low HDL-C subjects, displays reduced cholesterol efflux capacity

المؤلفون: Miriam Lee-Rueckert, Matti Jauhiainen, Jari Metso, Marja-Riitta Taskinen, Christian Ehnholm, Mikko Muilu, Riikka Vikstedt, Shuhei Nakanishi, Sanni Söderlund, Petri T. Kovanen, Anne Hiukka, Jussi Naukkarinen, Leena Palotie

المصدر: Journal of Lipid Research, Vol 50, Iss 2, Pp 183-192 (2009)

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Apolipoprotein B, QD415-436, 030204 cardiovascular system & hematology, Biochemistry, Monocytes, Excretion, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Endocrinology, Internal medicine, medicine, Macrophage, Humans, RNA, Messenger, Cells, Cultured, 030304 developmental biology, ATP Binding Cassette Transporter, Subfamily G, Member 1, 0303 health sciences, biology, Chemistry, Cholesterol, Macrophages, Reverse cholesterol transport, Cholesterol, HDL, nutritional and metabolic diseases, Cell Biology, Middle Aged, reverse cholesterol transport, lipoproteins, ATP Binding Cassette Transporter 1, ABCA1, Immunology, biology.protein, ATP-Binding Cassette Transporters, Female, lipids (amino acids, peptides, and proteins), Efflux, atherosclerosis, Foam Cells

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adeaf361ba8738a5741f8f24f34a5243Test
http://www.sciencedirect.com/science/article/pii/S0022227520414427Test

9

ABCG1 and ABCG4 are coexpressed in neurons and astrocytes of the CNS and regulate cholesterol homeostasis through SREBP-2

المؤلفون: Peter A. Edwards, Paul T. Tarr

المصدر: Journal of Lipid Research, Vol 49, Iss 1, Pp 169-182 (2008)

مصطلحات موضوعية: Lipoproteins, Central nervous system, Receptors, Cytoplasmic and Nuclear, ATP Binding Cassette Transporter, Subfamily G, Endosomes, QD415-436, Biology, Biochemistry, Mice, Endocrinology, sterol-regulatory element binding protein 2, medicine, Animals, ATP binding cassette transporters G1 and G4, RNA, Messenger, Liver X receptor, Cellular localization, ATP Binding Cassette Transporter, Subfamily G, Member 1, Liver X Receptors, Neurons, Messenger RNA, Microglia, Brain, Cell Biology, Lipid Metabolism, Orphan Nuclear Receptors, central nervous system, Molecular biology, Sterol regulatory element-binding protein, Cell biology, DNA-Binding Proteins, Mice, Inbred C57BL, Vesicular transport protein, Cholesterol, Endocytic vesicle, medicine.anatomical_structure, Astrocytes, ATP-Binding Cassette Transporters, lipids (amino acids, peptides, and proteins), Sterol Regulatory Element Binding Protein 2, liver X receptor

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75dd2c0a0359da0a04414e10fc69a728Test
https://doi.org/10.1194/jlr.m700364-jlr200Test

10

SR-BI inhibits ABCG1-stimulated net cholesterol efflux from cells to plasma HDL

المؤلفون: Alan R. Tall, May Brundert, Nan Wang, Takafumi Senokuchi, Tamara A. Pagler, Laurent Yvan-Charvet, Hongna Li, F. Rinninger

المصدر: Journal of Lipid Research, Vol 49, Iss 1, Pp 107-114 (2008)

مصطلحات موضوعية: medicine.medical_specialty, lecithin:cholesterol acyltransferase, Apolipoprotein B, Lipoproteins, Receptors, Cytoplasmic and Nuclear, macrophage, QD415-436, Transfection, Biochemistry, Cell Line, Phosphatidylcholine-Sterol O-Acyltransferase, Mice, chemistry.chemical_compound, Endocrinology, High-density lipoprotein, scavenger receptor class B type I, Internal medicine, medicine, Animals, Humans, RNA, Small Interfering, Scavenger receptor, Liver X receptor, ATP Binding Cassette Transporter, Subfamily G, Member 1, Liver X Receptors, ATP binding cassette transporter G1, biology, Cholesterol, Cholesterol, HDL, Reverse cholesterol transport, Cell Biology, Scavenger Receptors, Class B, Orphan Nuclear Receptors, Mice, Mutant Strains, DNA-Binding Proteins, Lipoproteins, LDL, chemistry, high density lipoprotein, ABCA1, Macrophages, Peritoneal, biology.protein, ATP-Binding Cassette Transporters, lipids (amino acids, peptides, and proteins), Cholesterol Esters, Efflux, Lipoproteins, HDL, liver X receptor

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b465fd308de9a005fb30e115d5eeab6Test
https://doi.org/10.1194/jlr.m700200-jlr200Test

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