دورية أكاديمية

Sexual Role and Transmission of HIV Type 1 among Men Who Have Sex with Men, in Peru.

التفاصيل البيبلوغرافية
العنوان: Sexual Role and Transmission of HIV Type 1 among Men Who Have Sex with Men, in Peru.
المؤلفون: Goodreau, Steven M.1 goodreau@u.washington.edu, Goicochea, L. Pedro2,3, Sanchez, Jorge3
المصدر: Journal of Infectious Diseases. 2/1/2005 Supplement, Vol. 191, pS147-S158. 12p.
مصطلحات موضوعية: *HIV infections, *HIV, *HIV infection transmission, *EPIDEMICS, *IMMUNITY
مصطلحات جغرافية: PERU
مستخلص: In Latin America, men who have sex with men (MSM) have traditionally practiced role segregation—that is, the adoption of a fixed role (insertive or receptive) rather than a versatile role (both practices) during anal sex. Previous modeling has shown that role segregation may yield a lower incidence of human immunodeficiency virus (HIV) type 1 infection, compared with role versatility; however, the modeling assumed no risk of acquiring HIV-1 during insertive sex, which is now recognized as unlikely. We reexamine the issue by use of a deterministic model incorporating bidirectional transmission and data from a cohort study of MSM in Lima, Peru, to demonstrate the potential effects of role segregation on the trajectory of the HIV-1 epidemic. In Lima, 67% of MSM reported segregated roles in their recent male partnerships. A population of MSM with identical contact rates but complete role versatility would have twice the prevalence of HIV-1 infection throughout the epidemic's first 3 decades. Preferential mixing among versatile MSM does not change overall prevalence but affects which individuals become infected. [ABSTRACT FROM AUTHOR]
قاعدة البيانات: Academic Search Index