Early and Significant Reduction in C-Reactive Protein Levels After Corticosteroid Therapy Is Associated With Reduced Mortality in Patients With COVID-19
| العنوان: | Early and Significant Reduction in C-Reactive Protein Levels After Corticosteroid Therapy Is Associated With Reduced Mortality in Patients With COVID-19 |
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| المؤلفون: | Zhu Cui, Leonidas Palaiodimos, Andrei Assa, William N. Southern, Erica Chung, Margaret E McCort, Zachary Merritt, Shitij Arora, Bibi Ayesha, Hashim Mustehsan, Anand Kumthekar, Yelena Averbukh, Sichen Liu, Sarah W. Baron |
| المصدر: | Journal of Hospital Medicine. 16:E1-E7 |
| بيانات النشر: | Wiley, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Male, medicine.medical_specialty, Reduced risk, Coronavirus disease 2019 (COVID-19), Leadership and Management, Assessment and Diagnosis, 03 medical and health sciences, 0302 clinical medicine, Adrenal Cortex Hormones, Internal medicine, Humans, Medicine, In patient, 030212 general & internal medicine, Care Planning, Aged, Retrospective Studies, 030304 developmental biology, 0303 health sciences, biology, SARS-CoV-2, business.industry, Health Policy, C-reactive protein, COVID-19, Retrospective cohort study, General Medicine, Odds ratio, Middle Aged, COVID-19 Drug Treatment, C-Reactive Protein, Corticosteroid therapy, biology.protein, Biomarker (medicine), Female, Fundamentals and skills, business, Biomarkers |
| الوصف: | BACKGROUND: Corticosteroids may be beneficial in a subset of patients with coronavirus disease 2019 (COVID-19), but predictors of therapeutic response remain unknown. C-reactive protein (CRP) is a routinely measured biomarker, and reduction in its levels after initiation of therapy may predict inpatient mortality. METHODS: In this retrospective cohort study, the charts of patients who were admitted to Montefiore Medical Center between March 10, 2020, and May 2, 2020 for the management of COVID-19 were examined. Of all patients who met inclusion criteria, patients who received corticosteroid treatment were categorized as CRP responders (≥50% CRP level reduction) and CRP nonresponders ( |
| تدمد: | 1553-5606 1553-5592 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62f24ed19069ce542201ec8a01257f03Test https://doi.org/10.12788/jhm.3560Test |
| رقم الانضمام: | edsair.doi.dedup.....62f24ed19069ce542201ec8a01257f03 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15535606 15535592 |
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