التفاصيل البيبلوغرافية
| العنوان: |
The potential impact of primary headache disorders on stroke risk. |
| المؤلفون: |
Tsai, Chia-Lin, Chou, Chung-Hsing, Lee, Pei-Jung, Yin, Jiu-Haw, Chen, Shao-Yuan, Lin, Chun-Chieh, Sung, Yueh-Feng, Yang, Fu-Chi, Chung, Chi-Hsiang, Chien, Wu-Chien, Tsai, Chia-Kuang, Lee, Jiunn-Tay |
| المصدر: |
Journal of Headache & Pain; 12/1/2016, Vol. 17 Issue 1, p1-7, 7p |
| مصطلحات موضوعية: |
STROKE risk factors, CHI-squared test, CONFIDENCE intervals, HEADACHE, PROBABILITY theory, RESEARCH funding, STATISTICAL sampling, COMORBIDITY, DISEASE incidence, PROPORTIONAL hazards models, RETROSPECTIVE studies, CASE-control method, DATA analysis software, KAPLAN-Meier estimator, DISEASE complications |
| مصطلحات جغرافية: |
TAIWAN |
| مستخلص: |
Background: Headache such as migraine is associated with stroke. Studies focused on primary headache disorders (PHDs) as a risk factor for stroke are limited. The purpose of this population-based cohort study was to explore whether patients with PHDs were at a high risk for developing stroke. Methods: A total of 1346 patients with PHDs were enrolled and compared with 5384 age-, gender- and co-morbidity-matched control cohorts. International Classification of Diseases, Clinical Modification codes were administered for the definition of PHDs, stroke, and stroke risk factors. Cox proportional-hazards regressions were performed for investigating hazard ratios (HR). Results: PHDs patients exhibited a 1.49 times (95% CI :1.15-1.98, p < 0.01) higher risk for developing ischaemic stroke compared with that of control cohorts. Both migraine (HR = 1.22, 95% CI :1.13-1.97, p < 0.05) and tension-type headache (HR = 2.29, 95% CI :1.22-2.80, p < 0.01) were associated with an increased risk of ischemic stroke. Females with PHDs were at greater risk of developing ischaemic stroke (HR = 1.49, 95% CI :1.13-1.90, p < 0.01) than those without PHDs. PHDs patient aged 45 to 64 years displayed significantly higher risk to develop ischaemic stroke (HR = 1.50, 95% CI: 1.11-2.10, p < 0.05) than the matched controls. The impact of PHDs on ischaemic stroke risk became gradually apparent by different following time intervals beyond 2 years after first diagnosis. Conclusion: PHDs is suggestive of an incremental risk for ischaemic stroke with gender-dependent, age-specific and time-dependent characteristics. [ABSTRACT FROM AUTHOR] |
|
Copyright of Journal of Headache & Pain is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| قاعدة البيانات: |
Complementary Index |
Full Text Finder