Evaluation of CA 242 as a Tumor Marker in Gallbladder Cancer
| العنوان: | Evaluation of CA 242 as a Tumor Marker in Gallbladder Cancer |
|---|---|
| المؤلفون: | Rajesh Gupta, R Pal, Satyavati Rana, Chander Kant Nain, Kartar Singh, Surinder Singh Rana, Kapil Jain, Birender Nagi, Radhika Srinivasan, Usha Dutta, Rakesh Kochhar |
| المصدر: | Journal of Gastrointestinal Cancer. 43:267-271 |
| بيانات النشر: | Springer Science and Business Media LLC, 2011. |
| سنة النشر: | 2011 |
| مصطلحات موضوعية: | Male, medicine.medical_specialty, CA-19-9 Antigen, CA 15-3, Enzyme-Linked Immunosorbent Assay, Sensitivity and Specificity, Gastroenterology, Pancreatic cancer, Internal medicine, Biomarkers, Tumor, medicine, Humans, Antigens, Tumor-Associated, Carbohydrate, Gallbladder cancer, Tumor marker, business.industry, Gallbladder, Gallstones, Middle Aged, medicine.disease, Carcinoembryonic Antigen, medicine.anatomical_structure, ROC Curve, Oncology, Area Under Curve, CA 242, Female, Gallbladder Neoplasms, CA19-9, business |
| الوصف: | Gallbladder and pancreas share common embryological origin, and malignancies of these organs may share common tumor antigens. CA 242 is a tumor marker for pancreatic cancer, but has not been studied in gallbladder cancer (GBC). We measured serum CA 242 levels in patients with GBC and compared it with those in patients with gallstones (GS) and healthy volunteers. We enrolled consecutive patients with GBC (cases), GS (disease controls), and healthy volunteers (healthy controls). Serum CA 242, CEA, and CA 19–9 levels were measured using ELISA. Receiver operator curve was plotted for all the three markers. We studied 117 patients with GBC, 58 with GS, and 10 healthy volunteers. Among patients with GBC, 81 (69%) also had GB calculi. Patients with GBC more often had elevated CA 242 levels (64%) compared to those with GS (17%; p |
| تدمد: | 1941-6636 1941-6628 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78fb2fd874918bd4c3bfb2c9e2c5f272Test https://doi.org/10.1007/s12029-011-9288-7Test |
| حقوق: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....78fb2fd874918bd4c3bfb2c9e2c5f272 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19416636 19416628 |
|---|