Deep‐learning system for real‐time differentiation between Crohn's disease, intestinal Behçet's disease, and intestinal tuberculosis
| العنوان: | Deep‐learning system for real‐time differentiation between Crohn's disease, intestinal Behçet's disease, and intestinal tuberculosis |
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| المؤلفون: | Jae Hee Cheon, Jun Gu Kang, Sung-Won Kim, Jung Min Kim |
| المصدر: | Journal of Gastroenterology and Hepatology. 36:2141-2148 |
| بيانات النشر: | Wiley, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Adult, Male, medicine.medical_specialty, Adolescent, Gastrointestinal Diseases, Colonoscopy, Behcet's disease, Disease, INTESTINAL TUBERCULOSIS, Gastroenterology, Diagnosis, Differential, Young Adult, 03 medical and health sciences, Deep Learning, 0302 clinical medicine, Crohn Disease, Internal medicine, medicine, Humans, Crohn's disease, Hepatology, Receiver operating characteristic, medicine.diagnostic_test, business.industry, Behcet Syndrome, Deep learning, Middle Aged, medicine.disease, Enteritis, Tuberculosis, Gastrointestinal, 030220 oncology & carcinogenesis, Female, 030211 gastroenterology & hepatology, Neural Networks, Computer, Artificial intelligence, Differential diagnosis, business |
| الوصف: | Background and aim Pattern analysis of big data can provide a superior direction for the clinical differentiation of diseases with similar endoscopic findings. This study aimed to develop a deep-learning algorithm that performs differential diagnosis between intestinal Behcet's disease (BD), Crohn's disease (CD), and intestinal tuberculosis (ITB) using colonoscopy images. Methods The typical pattern for each disease was defined as a typical image. We implemented a convolutional neural network (CNN) using Pytorch and visualized a deep-learning model through Gradient-weighted Class Activation Mapping. The performance of the algorithm was evaluated using the area under the receiver operating characteristic curve (AUROC). Results A total of 6617 colonoscopy images of 211 CD, 299 intestinal BD, and 217 ITB patients were used. The accuracy of the algorithm for discriminating the three diseases (all-images: 65.15% vs typical images: 72.01%, P = 0.024) and discriminating between intestinal BD and CD (all-images: 78.15% vs typical images: 85.62%, P = 0.010) was significantly different between all-images and typical images. The CNN clearly differentiated colonoscopy images of the diseases (AUROC from 0.7846 to 0.8586). Algorithmic prediction AUROC for typical images ranged from 0.8211 to 0.9360. Conclusion This study found that a deep-learning model can discriminate between colonoscopy images of intestinal BD, CD, and ITB. In particular, the algorithm demonstrated superior discrimination ability for typical images. This approach presents a beneficial method for the differential diagnosis of the diseases. |
| تدمد: | 1440-1746 0815-9319 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac3fe9f7b6b9d86be3fb92b219936afeTest https://doi.org/10.1111/jgh.15433Test |
| حقوق: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....ac3fe9f7b6b9d86be3fb92b219936afe |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14401746 08159319 |
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