دورية أكاديمية

Evaluation of endoscopic variceal ligation in prophylactic therapy for bleeding of oesophageal varices: A prospective, controlled trial compared with endoscopic injection sclerotherapy.

التفاصيل البيبلوغرافية
العنوان: Evaluation of endoscopic variceal ligation in prophylactic therapy for bleeding of oesophageal varices: A prospective, controlled trial compared with endoscopic injection sclerotherapy.
المؤلفون: Gotoh, Yudai, Iwakiri, Ryuichi, Sakata, Yasushi, Koyama, Takanori, Noda, Takahiro, Matsunaga, Chika, Ogata, Shin-Ichi, Ishibashi, Sadatoshi, Sakata, Hiroyuki, Tsunada, Seiji, Fujimoto, Kazuma
المصدر: Journal of Gastroenterology & Hepatology; Mar1999, Vol. 14 Issue 3, p241-244, 4p, 4 Charts, 1 Graph
مصطلحات موضوعية: LIGATURE (Surgery), ESOPHAGEAL varices, PENTAZOCINE, SCLEROTHERAPY
مستخلص: Background: To evaluate the efficacy of endoscopic variceal ligation (EVL) in prophylactic therapy for oesophageal varices, we performed a randomized prospective trial to compare the recurrence of oesophageal varices treated by EVL with those treated by endoscopic injection sclerotherapy. Methods: Fifty patients with liver cirrhosis were divided into two groups at random, after informed consents were obtained, to receive prophylactic therapy for bleeding of oesophageal varices. Group 1 patients underwent sessions of sclerotherapy with 5% ethanolamine oleate used as the sclerosant. Group 2 patients underwent EVL followed by one or two sessions of sclerotherapy. Results: During the 18 month follow-up period, both the recurrence rate in group 2 (56%) and the incidence of bleeding (20%) were significantly higher compared with group 1 (recurrence rate 16%, bleeding 0%). Conclusions: This result indicates that EVL is not effective for prophylactic therapy for oesophageal varices in liver cirrhosis. [ABSTRACT FROM AUTHOR]
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قاعدة البيانات: Complementary Index
الوصف
تدمد:08159319
DOI:10.1046/j.1440-1746.1999.01841.x