Human metapneumovirus in patients hospitalized with acute respiratory infections: A meta-analysis
| العنوان: | Human metapneumovirus in patients hospitalized with acute respiratory infections: A meta-analysis |
|---|---|
| المؤلفون: | Pierre Pothier, Ludwig Serge Aho-Glélé, Isabelle Fournel, Rachid Abbas, K. Astruc, Michel Tiv, Jean-Baptiste Bour, A. Lefebvre, Catherine Manoha |
| المصدر: | Journal of Clinical Virology |
| بيانات النشر: | Elsevier BV, 2016. |
| سنة النشر: | 2016 |
| مصطلحات موضوعية: | 0301 basic medicine, Pediatrics, medicine.medical_specialty, viruses, 030106 microbiology, Respiratory virus, Article, 03 medical and health sciences, 0302 clinical medicine, Human metapneumovirus, Virology, Prevalence, Humans, Medicine, Metapneumovirus, 030212 general & internal medicine, Paramyxoviridae Infections, biology, business.industry, Incidence (epidemiology), virus diseases, Respiratory infection, biology.organism_classification, respiratory tract diseases, Hospitalization, Meta-analysis, Infectious Diseases, Acute respiratory infection, Etiology, Observational study, business |
| الوصف: | Highlights • 6% of acute respiratory infections were linked to human metapneumovirus. • High heterogeneity was observed. • HMPV should be taken into account as a possible etiology in hospitalized ARI. This meta-analysis aimed to estimate the prevalence of human metapneumovirus (hMPV) infections in patients hospitalized for acute respiratory infection (ARI) and to study factors associated with this prevalence. Medline and ScienceDirect databases were searched for prospective observational studies that screened hospitalized patients with ARI for hMPV by RT-PCR, with data available at December 27, 2014. The risk of bias was assessed regarding participation rate, definition of ARI, description of diagnostic technique, method of inclusion identical for all subjects, standardized and identical sampling method for all subjects, analysis performed according to the relevant subgroups, and presentation of data sources. Random-effect meta-analysis with arcsine transformation and meta-regressions was used. In the 75 articles included, the prevalence of hMPV among hospitalized ARI was 6.24% (95% CI 5.25–7.30). An effect of the duration of the inclusion period was observed (p = 0.0114), with a higher prevalence of hMPV in studies conducted during periods of 7–11 months (10.56%, 95% CI 5.97–16.27) or complete years (7.55%, 95% CI 5.90–9.38) than in periods of 6 months or less (5.36%, 95% CI 4.29–6.54). A significant increase in the incidence with increasing distance from the equator was observed (p = 0.0384). hMPV should be taken into account as a possible etiology in hospitalized ARI. |
| تدمد: | 1386-6532 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cefaeb83980d42642ef5ef09c4eb4ecTest https://doi.org/10.1016/j.jcv.2016.05.015Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....7cefaeb83980d42642ef5ef09c4eb4ec |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 13866532 |
|---|