Diffuse midline glioma presenting with central sleep apnea and pulmonary hypertension in a 4-year-old patient: a case report
| العنوان: | Diffuse midline glioma presenting with central sleep apnea and pulmonary hypertension in a 4-year-old patient: a case report |
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| المؤلفون: | Mei-Hwan Wu, Jou-Kou Wang, Meng-Fai Kuo, Pei-Lin Lee, Ming-Tai Lin, Chun-An Chen, Pi-Chuan Fan, Chun-Wei Lu, Shuenn-Nan Chiu, Szu Wei Huang |
| المصدر: | J Clin Sleep Med |
| بيانات النشر: | American Academy of Sleep Medicine (AASM), 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Pulmonary and Respiratory Medicine, Pediatrics, medicine.medical_specialty, Central sleep apnea, biology, business.industry, Syncope (genus), Case Reports, Brain stem glioma, medicine.disease, biology.organism_classification, Pulmonary hypertension, Neurology, Apnea–hypopnea index, Glioma, medicine, Brainstem glioma, Neurology (clinical), business, Pediatric population |
| الوصف: | Central sleep apnea is a rare disorder in the pediatric population with various initial presentations and is secondary to many underlying diseases. We report on a 4-year-old boy with episodes of syncope. He also had pulmonary hypertension and cardiomegaly. Polysomnography showed the finding for central sleep apnea with a high apnea-hypopnea index (up to 138.1 events/h). Brain magnetic resonance imaging showed an ill-defined area near the medulla oblongata and lower pons. The lesion from a brainstem biopsy confirmed the diagnosis of low-grade glioma. Conservative medical follow-up was suggested, and brain magnetic resonance imaging 6 months later showed no obvious tumor progression. To our best knowledge, this is the first case report that workup on the cause of syncope and pulmonary hypertension led to the final diagnosis of central sleep apnea and a brain neoplasm. CITATION: Huang S-W, Lee P-L, Fan P-C, et al. Diffuse midline glioma presenting with central sleep apnea and pulmonary hypertension in a 4-year-old patient: a case report. J Clin Sleep Med. 2021;17(2):325–328. |
| تدمد: | 1550-9397 1550-9389 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f80555994067c4a99ca5131977e1875Test https://doi.org/10.5664/jcsm.8854Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....3f80555994067c4a99ca5131977e1875 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15509397 15509389 |
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