التفاصيل البيبلوغرافية
| العنوان: |
Hyperglycemia and Hypoglycemia Are Associated with In-Hospital Mortality among Patients with Coronavirus Disease 2019 Supported with Extracorporeal Membrane Oxygenation. |
| المؤلفون: |
Son, Kuk Hui, Kim, Woong-Han, Kwak, Jae Gun, Choi, Chang-Hyu, Lee, Seok In, Ko, Ui Won, Kim, Hyoung Soo, Lee, Haeyoung, Chung, Euy Suk, Kim, Jae-Bum, Jang, Woo Sung, Jung, Jae Seung, Kim, Jieon, Yoon, Young Kyung, Song, Seunghwan, Sung, Minji, Jang, Myung Hun, Kim, Young Sam, Jeong, In-Seok, Kim, Do Wan |
| المصدر: |
Journal of Clinical Medicine; Sep2022, Vol. 11 Issue 17, p5106, 12p |
| مصطلحات موضوعية: |
COVID-19, EXTRACORPOREAL membrane oxygenation, HOSPITAL mortality, HYPOGLYCEMIA, HYPERGLYCEMIA, MORTALITY risk factors |
| مستخلص: |
Metabolic abnormalities, such as preexisting diabetes or hyperglycemia or hypoglycemia during hospitalization aggravated the severity of COVID-19. We evaluated whether diabetes history, hyperglycemia before and during extracorporeal membrane oxygenation (ECMO) support, and hypoglycemia were risk factors for mortality in patients with COVID-19. This study included data on 195 patients with COVID-19, who were aged ≥19 years and were treated with ECMO. The proportion of patients with diabetes history among nonsurvivors was higher than that among survivors. Univariate Cox regression analysis showed that in-hospital mortality after ECMO support was associated with diabetes history, renal replacement therapy (RRT), and body mass index (BMI) < 18.5 kg/m2. Glucose at admission >200 mg/dL and glucose levels before ventilator >200 mg/dL were not associated with in-hospital mortality. However, glucose levels before ECMO >200 mg/dL and minimal glucose levels during hospitalization <70 mg/dL were associated with in-hospital mortality. Multivariable Cox regression analysis showed that glucose >200 mg/dL before ECMO and minimal glucose <70 mg/dL during hospitalization remained risk factors for in-hospital mortality after adjustment for age, BMI, and RRT. In conclusion, glucose >200 mg/dL before ECMO and minimal glucose level <70 mg/dL during hospitalization were risk factors for in-hospital mortality among COVID-19 patients who underwent ECMO. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
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