المؤلفون: Liyun Ding, Matthew P. Coghlan, Ellen P.S. Conceição Furber, Jorge Alsina-Fernandez, Kyle W. Sloop, Brian A. Droz, Mridula Dogra, Annie M. Long, Michael E. Christe, Tamer Coskun, Ruth E. Gimeno, Xiaoping Ruan, Jill A. Willency, William C. Roell, Debra L. Konkol, Adrienne K. Holland, Ricardo J. Samms, Jessica L. Friedrich, Libbey S. O’Farrell, Valentina Pirro, Over Cabrera, Daniel A. Briere, Richard Cosgrove, Samantha Wojnicki, Kyla A.L. Collins, Julie S. Moyers, Yanzhu Lin, Christine C. Cheng

المصدر: J Clin Invest

مصطلحات موضوعية: 0301 basic medicine, Agonist, medicine.medical_specialty, medicine.drug_class, Adipose Tissue, White, medicine.medical_treatment, Gastric Inhibitory Polypeptide, White adipose tissue, Type 2 diabetes, Glucagon-Like Peptide-1 Receptor, Mice, 03 medical and health sciences, 0302 clinical medicine, Downregulation and upregulation, Internal medicine, Diabetes mellitus, Brown adipose tissue, medicine, Animals, Obesity, Sensitization, Mice, Knockout, business.industry, Insulin, Body Weight, General Medicine, medicine.disease, 030104 developmental biology, medicine.anatomical_structure, Endocrinology, 030220 oncology & carcinogenesis, Insulin Resistance, business, Amino Acids, Branched-Chain, hormones, hormone substitutes, and hormone antagonists, Research Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a4281cb2d7c4426d2de7cba245f46e9Test
https://doi.org/10.1172/jci146353Test

المؤلفون: David A. D'Alessio, Jonathan E. Campbell

المصدر: Journal of Clinical Investigation. 127:793-795

مصطلحات موضوعية: Neurons, 0301 basic medicine, Brain, Stimulation, General Medicine, Biology, Proglucagon, Glucagon-Like Peptide-1 Receptor, Mice, 03 medical and health sciences, 030104 developmental biology, medicine.anatomical_structure, Metabolic regulation, In vivo, Drug Design, Commentary, medicine, Animals, Humans, Glucose homeostasis, Neuron, Receptor, Neuroscience, Function (biology)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1514de168fe171e7e06e1b73ffd75adaTest
https://doi.org/10.1172/jci92845Test

المؤلفون: Jacovetti Cécile, Abderrahmani Amar, Parnaud Géraldine, Jonas Jean Christophe, Peyot Marie Line, Cornu Marion, Laybutt Ross, Meugnier Emmanuelle, Rome Sophie, Thorens Bernard, Prentki Marc, Bosco Domenico, Regazzi Romano

المساهمون: Université de Lausanne (UNIL), Metabolic functional (epi)genomics and molecular mechanisms involved in type 2 diabetes and related diseases - UMR 8199 - UMR 1283 (GI3M), Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre National de la Recherche Scientifique (CNRS), Department of Surgery, University of Geneva [Switzerland], Université Catholique de Louvain = Catholic University of Louvain (UCL), Centre Hospitalier de l'Université de Montréal (CHUM), Université de Montréal (UdeM), St. Vincent's Hospital, Sydney, Cardiovasculaire, métabolisme, diabétologie et nutrition (CarMeN), Hospices Civils de Lyon (HCL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Institut National des Sciences Appliquées (INSA)-Université de Lyon-Institut National des Sciences Appliquées (INSA)-Université de Lyon-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Institut National de la Recherche Agronomique (INRA), This work was supported by grants of the Swiss National Science Foundation (31003A-127254 to R. Regazzi, 32003B-120376 to D. Bosco), European Foundation for the Study of Diabetes (to R. Regazzi), Société Francophone du Diabète (to C. Jacovetti), National Health and Medical Research Council of Australia (1030715 to R. Laybutt), Fondation pour la Recherche Médicale (to S. Rome), Association Française de recherche sur les Myopathies (to S. Rome), Association Française de Diabétologie (to S. Rome), and Canadian Diabetes Association (to M. Prentki)., We thank Corinne Sinigaglia (Cell Isolation and Transplantation Center, Geneva University, Geneva, Switzerland) for technical assistance., Université de Lausanne = University of Lausanne (UNIL), Metabolic functional (epi)genomics and molecular mechanisms involved in type 2 diabetes and related diseases - UMR 8199 - UMR 1283 (EGENODIA (GI3M)), Université de Genève = University of Geneva (UNIGE), Institut National de la Recherche Agronomique (INRA)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Hospices Civils de Lyon (HCL)-Institut National de la Santé et de la Recherche Médicale (INSERM), Génomique Intégrative et Modélisation des Maladies Métaboliques (EGID), Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille)-Centre National de la Recherche Scientifique (CNRS), Université Catholique de Louvain (UCL), Université de Montréal [Montréal], Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Hospices Civils de Lyon (HCL), Université de Lille-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Centre National de la Recherche Scientifique (CNRS)-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille)

المصدر: Journal of Clinical Investigation
Journal of Clinical Investigation, American Society for Clinical Investigation, 2012, 122 (10), pp.3541-3551. ⟨10.1172/JCI64151⟩
Journal of Clinical Investigation, 2012, 122 (10), pp.3541-3551. ⟨10.1172/JCI64151⟩
Journal of Clinical Investigation, vol. 122, no. 10, pp. 3541-3551
The Journal of clinical investigation

مصطلحات موضوعية: Male, PLACENTAL-LACTOGEN, [SDV]Life Sciences [q-bio], Estrogen receptor, Receptors, G-Protein-Coupled, Mice, 0302 clinical medicine, Glucagon-Like Peptide 1, Pregnancy, Receptors, Glucagon, Receptor, Fulvestrant, Cells, Cultured, 0303 health sciences, geography.geographical_feature_category, Estradiol, Postpartum Period, Estrogen Antagonists, PROLIFERATION, Organ Size, General Medicine, Islet, Adaptation, Physiological, PROTEIN-COUPLED RECEPTOR, ESTROGEN, medicine.anatomical_structure, PROBE LEVEL, Cytokines, Female, GPER, Signal Transduction, Research Article, EXPRESSION, medicine.medical_specialty, 030209 endocrinology & metabolism, Biology, MASS, INSULIN-SECRETION, Glucagon-Like Peptide-1 Receptor, Islets of Langerhans, 03 medical and health sciences, Insulin resistance, Internal medicine, Diabetes mellitus, microRNA, medicine, Animals, Obesity, Rats, Wistar, 030304 developmental biology, geography, Pancreatic islets, DIABETES-MELLITUS, PANCREATIC-ISLETS, medicine.disease, Mice, Mutant Strains, Rats, MicroRNAs, Endocrinology, Gene Expression Regulation, Insulin Resistance

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f189b662c37d5496272c355c52e821c4Test