دورية أكاديمية
Serum Fluorescence of Advanced Glycation End Products: A Potential Screening Tool to Distinguish Between Diabetic Patients with and without Microvascular Complications
| العنوان: | Serum Fluorescence of Advanced Glycation End Products: A Potential Screening Tool to Distinguish Between Diabetic Patients with and without Microvascular Complications |
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| المؤلفون: | Sadaf Ali, Nivedita L Rao |
| المصدر: | Journal of Clinical and Diagnostic Research, Vol 14, Iss 11, Pp BC06-BC09 (2020) |
| بيانات النشر: | JCDR Research and Publications Private Limited, 2020. |
| سنة النشر: | 2020 |
| المجموعة: | LCC:Medicine |
| مصطلحات موضوعية: | diabetes mellitus, neuropathy, retinopathy, spectrofluorometry, Medicine |
| الوصف: | Introduction: Enhanced formation and accumulation of Fluorescent Advanced Glycation End products (F-AGEs) in diabetes mellitus have been linked to increased risk of developing the associated vascular complications. Aim: To evaluate the potential of serum fluorescence levels of F-AGEs as screening tools to distinguish between type 2 diabetic patients with and without microvascular complications such as retinopathy, neuropathy. Materials and Methods: This cross-sectional study was conducted between June 2016 and June 2017, included 95 type 2 diabetic patients with more than 1 year of diabetes duration. Fasting blood glucose, glycated haemoglobin and total protein levels were estimated by automated methods. Serum F-AGEs were estimated by using a simple spectrofluorometric method. Microvascular complications due to diabetes mellitus were studied in each patient from medical records data on fundus examination for retinopathy and touch, vibration sensation detection for neuropathy. Diabetic patients were categorised into two groups as those without microvascular complications and those with microvascular complications-retinopathy and neuropathy. Statistical tests used for comparisons between groups were chi-square test for gender distribution, independent t-test for other parameters and Pearson’s correlations. The p-value |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2249-782X 0973-709X 30347033 |
| العلاقة: | https://jcdr.net/articles/PDF/14191/45484_CETest[Ra1]_F(SL)_PF1(AKA_KM)_PN(SL).pdf; https://doaj.org/toc/2249-782XTest; https://doaj.org/toc/0973-709XTest |
| DOI: | 10.7860/JCDR/2020/45484.14191 |
| الوصول الحر: | https://doaj.org/article/29261c589b38473a8b9d4f303470331eTest |
| رقم الانضمام: | edsdoj.29261c589b38473a8b9d4f303470331e |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 2249782X 0973709X 30347033 |
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| DOI: | 10.7860/JCDR/2020/45484.14191 |