التفاصيل البيبلوغرافية
| العنوان: |
Oxidative stress in rats exercised at different intensities. |
| المؤلفون: |
de Araújo, Michel Barbosa1 mbujo@ig.com.br, Voltarelli, Fabrício Azevedo1, Ledesma Contarteze, Ricardo Vinícius1, Manchado-Gobatto, Fülvia de Barros1, de Mello, Maria Alice Rostom1 |
| المصدر: |
Journal of Chinese Clinical Medicine. 2009, Vol. 4 Issue 1, p11-18. 8p. 4 Graphs. |
| مصطلحات موضوعية: |
*PHYSICAL training & conditioning, *AEROBIC exercises, *OXIDATIVE stress, *BIOMARKERS, *LABORATORY mice, *ALKALINE phosphatase, *ANTIOXIDANTS, *ANAEROBIC capacity, *EXERCISE intensity |
| مستخلص: |
Objective The present study aimed to analyze the effects of physical training at different intensities on aerobic conditioning and oxidative stress biomarkers in rats. Methods Wistar rats (90 d of age) weighing 250 - 320 g at the beginning of the experiment had the aerobic / anaerobic metabolic transition determined by maximal lactate steady state test (MLSS). The rats were trained during 40 min/d ,5 d/week ,at the speed equivalent to MLSS (MT) or 25% above it (AT). ,during 8 weeks. As controls ,rats maintained sedentary (S) were used. At the end, all rats were sacrificed in order to analyze biomarkers of the lipid peroxidation : concentration of substances that react to thiobarbituric acids (TBARs) ;antioxidant status:catalase activity (CAT) and cellular activity:alkaline phosphatase activity (AP) in different organs including muscle gastrocnemius,liver, brain and blood. Results Physical training at intensities equivalent to the metabolic transition and 25% above it improved the aerobic conditioning of the animals. Exercise-training at both intensities probably induced antioxidant compensatory responses which avoided tissue lipid peroxidation. Conclusion These results suggest that, at least in part, that the antioxidant defense mechanisms showed adaptative responses to training in the different ways, in the different organs and tissues analyzed. [ABSTRACT FROM AUTHOR] |
| قاعدة البيانات: |
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