التفاصيل البيبلوغرافية
| العنوان: |
Spectrum and Prevalence of Vasculopathy in Pediatric Neurofibromatosis Type 1. |
| المؤلفون: |
Kaas, Bonnie, Huisman, Thierry A. G. M., Tekes, Aylin, Bergner, Amanda, Blakeley, Jaishri O., Jordan, Lori C. |
| المصدر: |
Journal of Child Neurology; May2013, Vol. 28 Issue 5, p561-569, 9p |
| مصطلحات موضوعية: |
NEUROFIBROMATOSIS, PHAKOMATOSES, MOYAMOYA disease, PEDIATRICS, PERIPHERAL vascular diseases, NEUROFIBROMA, GLIOMAS, PATIENTS, DIAGNOSIS |
| مستخلص: |
To describe the spectrum and associated clinical features of peripheral and cerebral vasculopathy in pediatric patients with neurofibromatosis type 1, children seen at a single center from 2000 to 2010 with appropriate imaging studies were identified. Scans were assessed for vascular disease by 2 pediatric neuroradiologists. Of 181 children, 80 had pertinent imaging studies: 77 had brain imaging, 6 had peripheral imaging, and 3 had both. Vasculopathy was identified in 14/80 children (18%, minimum prevalence of 14/181; 8%). Of those with vascular abnormalities, 2/14 had peripheral vasculopathy (1% minimum prevalence) and 12/14 had cerebrovascular abnormalities (7% minimum prevalence). No associations were found between vasculopathy and common clinical features of neurofibromatosis type 1, including optic pathway glioma, plexiform neurofibroma, skeletal abnormalities, attention-deficit hyperactivity disorder (ADHD), or suspected learning disability. Both peripheral and cerebral vasculopathy are important complications of pediatric neurofibromatosis type 1 and should be considered in the management of this complex disease. [ABSTRACT FROM AUTHOR] |
|
Copyright of Journal of Child Neurology is the property of Sage Publications Inc. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| قاعدة البيانات: |
Complementary Index |
