E11/Podoplanin Protein Stabilization Through Inhibition of the Proteasome Promotes Osteocyte Differentiation in Murine in Vitro Models
| العنوان: | E11/Podoplanin Protein Stabilization Through Inhibition of the Proteasome Promotes Osteocyte Differentiation in Murine in Vitro Models |
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| المؤلفون: | Staines, Katherine A., Prideaux, Matt, Allen, Steve, Buttle, David J., Pitsillides, Andrew A., Farquharson, Colin |
| المصدر: | Journal of Cellular Physiology |
| بيانات النشر: | John Wiley and Sons Inc., 2015. |
| سنة النشر: | 2015 |
| مصطلحات موضوعية: | Biomedical Science Research Group, rho GTP-Binding Proteins, Proteasome Endopeptidase Complex, Time Factors, Physiology, Clinical Biochemistry, Cysteine Proteinase Inhibitors, Transfection, Osteocytes, Cell Line, 571 Physiology & related subjects, Original Research Articles, Animals, Original Research Article, RNA, Messenger, QP Physiology, Membrane Glycoproteins, Osteoblasts, Dose-Response Relationship, Drug, Calpain, Protein Stability, Ubiquitination, Cell Differentiation, Cell Biology, Mice, Inbred C57BL, Phenotype, Health, embryonic structures, Proteolysis, rhoA GTP-Binding Protein, Proteasome Inhibitors |
| الوصف: | The transmembrane glycoprotein E11 is considered critical in early osteoblast–osteocyte transitions (osteocytogenesis), however its function and regulatory mechanisms are still unknown. Using the late osteoblast MLO‐A5 cell line we reveal increased E11 protein/mRNA expression (P |
| وصف الملف: | |
| اللغة: | English |
| تدمد: | 1097-4652 0021-9541 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::6bd91a47b97f5dd490b30bec73752a03Test http://europepmc.org/articles/PMC4832367Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.pmid.dedup....6bd91a47b97f5dd490b30bec73752a03 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 10974652 00219541 |
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