التفاصيل البيبلوغرافية
| العنوان: |
Electrophysiological findings during atrial fibrillation reablation: Extending from pulmonary vein reconnection to sequential bipolar voltage map information. |
| المؤلفون: |
Huo, Yan, Kronborg, Mads Brix, Richter, Utz, Guo, Jianping, Ulbrich, Stefan, Zedda, Angela M., Kirstein, Bettina, Mayer, Julia, Pu, Liying, Piorkowski, Judith, Wagner, Michael, Gaspar, Thomas, Piorkowski, Christopher |
| المصدر: |
Journal of Cardiovascular Electrophysiology; Apr2020, Vol. 31 Issue 4, p885-894, 10p, 2 Illustrations, 1 Diagram, 3 Charts, 2 Graphs |
| مصطلحات موضوعية: |
ATRIAL fibrillation, BODY surface mapping, CATHETER ablation, ELECTROPHYSIOLOGY, PATIENT aftercare, PULMONARY veins, STATISTICS, DISEASE relapse, QUANTITATIVE research, DISEASE prevalence, DESCRIPTIVE statistics |
| مستخلص: |
Background: Left atrial substrate modification targeting low voltage zones (LVZ) is an ablation strategy that—in addition to pulmonary vein (PV) isolation—tries to eliminate arrhythmogenic mechanisms harbored in such tissue. Electrophysiological findings at reablation include (a) PV reconnection, (b) reconnection over previous substrate ablation, and (c) de‐novo LVZ. Objective: To study, prevalence and contribution of these arrhythmogenic electrophysiological entities in patients with atrial fibrillation (AF) recurrences. Methods: Consecutive patients with highly symptomatic AF undergoing index and reablation were included (n = 113). In all patients' PV reconnection, reconnection over previous substrate ablation and spontaneous de‐novo LVZ were quantitatively assessed and integrated into an individual reablation strategy. Follow‐up was based on continuous device monitoring. Results: At re‐do procedure, 45 out of 113 (39.8%) patients showed PV reconnection as the only electrophysiological abnormality. Reconduction over previous lines was the only electrophysiological abnormality in 8 out of 113 (7.1%) patients. Spontaneous de‐novo LVZ was the only electrophysiological abnormality in 12 out of 113 (10.6%) patients. Combined findings of PV reconnection, line reconduction, and/or spontaneous de‐novo LVZ were seen in 40 out of 113 (35.4%) patients. No detectable electrophysiological abnormality was observed in 8 out of 113 (7.1%) patients. In univariate analysis, none of the tested electrophysiological characteristics independently predicted the outcome after re‐do. Conclusions: In patients undergoing reablation, we could show that reconduction over previous substrate ablation as well as the development of new low voltage areas are frequent findings besides classical PV reconnection—without a clear leading cause for recurrences. These findings impact reablation strategies as well as the strategic focus during index procedures. [ABSTRACT FROM AUTHOR] |
|
Copyright of Journal of Cardiovascular Electrophysiology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| قاعدة البيانات: |
Complementary Index |
