المؤلفون: Yue Sun, Galahad Deperalta, Saeed Izadi, Matthew D. Callahan, Aaron T. Wecksler

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: 0301 basic medicine, Glycosylation, Protein Conformation, DNA Mutational Analysis, Receptors, Fc, Biochemistry, Fragment antigen-binding, Receptor, FA, formic acid, Antibody-dependent cell-mediated cytotoxicity, biology, Chemistry, Editors' Pick, afucosylation, N297, asparagine 297, Fab, fragment antigen-binding, Antibody, mAbs, monoclonal antibodies, Research Article, antibody-dependent cellular cytotoxicity, Protein Binding, Glycan, Fuc, fucose, medicine.drug_class, Fab–Fc receptor interactions, CHO Cells, LC, light chain, Molecular Dynamics Simulation, Immunoglobulin light chain, Monoclonal antibody, CHO, Chinese hamster ovary, fast photochemical oxidation of proteins (FPOP), Immunoglobulin Fab Fragments, 03 medical and health sciences, FcγRIIIa, Cricetulus, nG0-F, normalized G0-F, medicine, Animals, Molecular Biology, Fucose, mAb, IgG1, immunoglobulin G1, ADCC, antibody-dependent cellular cytotoxicity, 030102 biochemistry & molecular biology, Hydroxyl Radical, IgG1, HC, heavy chain, Antibody-Dependent Cell Cytotoxicity, SASA, solvent-accessible surface area, Cell Biology, Fragment crystallizable region, molecular dynamics, 030104 developmental biology, Immunoglobulin G, Mutation, hydroxyl radical footprinting-mass spectrometry, biology.protein, Biophysics, HRF, hydroxyl radical footprint, HDX, hydrogen–deuterium exchange

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc1434bc455747921029f61b4b0ee4f0Test
https://doi.org/10.1016/j.jbc.2021.100826Test

المؤلفون: Bernhard C. Lechtenberg, Maricel Gomez-Soler, Marina P. Gehring, Zichen Wang, Taylor P. Light, Kelly Karl, Elena B. Pasquale, Taras V. Pogorelov, Kalina Hristova, Elmer Zapata-Mercado

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: 0301 basic medicine, Mutant, Mutation, Missense, DMEM, Dulbecco’s modified eagle medium, medicine.disease_cause, Biochemistry, Receptor tyrosine kinase, RMSD, root mean square deviation, FIF, fluorescence intensity fluctuation, 03 medical and health sciences, PBS, phosphate buffered saline, Neoplasms, melanoma, medicine, Humans, LDS, lithium dodecyl sulfate, Ephrin, FSI, fully quantified spectral imaging, Kinase activity, Molecular Biology, SAM, sterile alpha motif, Mutation, FRET, Föster resonance energy transfer, 030102 biochemistry & molecular biology, biology, phosphorylation, Chemistry, Autophosphorylation, Receptor, EphA4, Erythropoietin-producing hepatocellular (Eph) receptor, HRP, horseradish peroxidase, Cell Biology, ALS, amyotrophic lateral sclerosis, MD, molecular dynamics, molecular dynamics, Cell biology, Sterile Alpha Motif, HEK293 Cells, 030104 developmental biology, receptor tyrosine kinase, FRET, MSE, mean squared error, biology.protein, SASA, solvent accessible surface area, Protein Multimerization, Sterile alpha motif, Signal Transduction, Research Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3935e9df6565e4ef06f9dce1b7624c7Test
https://doi.org/10.1016/j.jbc.2021.100876Test

المؤلفون: Christian J. Muñoz Sosa, Maria E. Carrizo, Federico M. Issoglio

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: Models, Molecular, 0301 basic medicine, RING, Really Interesting New Gene, Protein Conformation, RMSD, Root Mean Square Deviation, B30.2-SPRY Domain, Crystallography, X-Ray, Biochemistry, Tripartite Motif Proteins, GN1, glycogenin-1, TRIM7, CD, circular dichroism, SOCS, suppressor of cytokine signaling, Coiled coil, biology, Chemistry, BTN3A1, Butyrophilin 3A1, computer.file_format, PRY-SPRY, Ubiquitin ligase, E3 ubiquitin ligase, Glucosyltransferases, site-directed mutagenesis, glycogenin, Research Article, CBD, chitin-binding domain, crystal structure, Ubiquitin-Protein Ligases, Computational biology, MD, Molecular Dynamics, Antiparallel (biochemistry), CC, coiled-coil, Protein–protein interaction, 03 medical and health sciences, B30.2, PDB, Protein Data Bank, Humans, Molecular Biology, Glycoproteins, TRIM, TRIpartite Motif, Binding Sites, 030102 biochemistry & molecular biology, C-terminus, Cell Biology, Protein Data Bank, molecular dynamics, protein–protein interaction, 030104 developmental biology, GNIP, Glycogen Interacting Protein, biology.protein, SASA, solvent accessible surface area, TRIM Motif, TRIM Family, computer

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2597aa278709ef8e63b06f58122a91fbTest
https://doi.org/10.1016/j.jbc.2021.100772Test