المؤلفون: Jared J. Lindenberger, Nicholas E. Powers, Karsten Beckmann, Liqiong Jiang, Suzhao Li, Stephan Fischer, Dennis M. de Graaf, Ulrich Pessara, Charles A. Dinarello, Jesper F Højen, Elan Z. Eisenmesser, Tania Azam

المصدر: Li, S, Jiang, L, Beckmann, K, Højen, J F, Pessara, U, Powers, N E, de Graaf, D M, Azam, T, Lindenberger, J, Eisenmesser, E Z, Fischer, S & Dinarello, C A 2021, ' A novel anti-human IL-1R7 antibody reduces IL-18-mediated inflammatory signaling ', The Journal of Biological Chemistry, vol. 296, 100630 . https://doi.org/10.1016/J.JBC.2021.100630Test
The Journal of Biological Chemistry

مصطلحات موضوعية: Lipopolysaccharides, 0301 basic medicine, medicine.medical_treatment, Anti-Inflammatory Agents, Biochemistry, Candida albicans, Interferon gamma, Receptor, Research Articles, Receptors, Interleukin-18, Chemistry, Macrophage Activation Syndrome, Interleukin-18, NF-kappa B, Antibodies, Monoclonal, interleukin-18 (IL-18), Cytokine, Interleukin 18, Tumor necrosis factor alpha, medicine.symptom, Signal transduction, Signal Transduction, medicine.drug, Primary Cell Culture, Inflammation, macrophage activation syndrome (MAS), Proinflammatory cytokine, Interferon-gamma, 03 medical and health sciences, medicine, Humans, Immunologic Factors, Molecular Biology, 030102 biochemistry & molecular biology, Interleukin-6, SARS-CoV-2, Tumor Necrosis Factor-alpha, COVID-19, blockade, Cell Biology, Antibodies, Neutralizing, COVID-19 Drug Treatment, therapeutic, HEK293 Cells, 030104 developmental biology, Gene Expression Regulation, Immunology, Leukocytes, Mononuclear, IL-1 receptor 7 (IL-1R7), IFNγ

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::851f20ff30c87257bb17818022c0f22aTest
https://doi.org/10.1016/j.jbc.2021.100630Test

المؤلفون: Peter D. Mace, James M. Murphy

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: RAF, rapidly accelerated fibrosarcoma kinase, 0301 basic medicine, dead enzyme, KSR, kinase suppressor of Ras, MLKL, mixed lineage kinase domain-like, Biochemistry, PEAK, pseudopodium-enriched atypical kinase, RKS1, resistance-related kinase 1, Protein structure, PsK, pseudokinase, IRAK, IL-1 receptor-associated kinase, RIPK, receptor interacting serine/threonine kinase, biology, Chemistry, Kinase, protein kinase, ILK, integrin-linked kinase, Cell biology, PABPs, poly(A)-binding proteins, ULK4, Unc-51-like kinase 4, Signal transduction, JAK, Janus kinase, Signal Transduction, Cell signaling, PK-1, protein kinase-1, DSF, differential scanning fluorimetry, Catalysis, 03 medical and health sciences, Allosteric Regulation, HER, Receptor tyrosine-protein kinase erbB, Integrin-linked kinase, protein structure, Kinase activity, Protein kinase A, Molecular Biology, BUBR1, BUB1 related-1, 030102 biochemistry & molecular biology, JBC Reviews, SgK, Sugen kinase, HDX-MS, hydrogen-deuterium exchange mass spectrometry, Cell Biology, nonenzyme, EGFR, epidermal growth factor receptor, 030104 developmental biology, pseudoenzyme, biology.protein, TRIB, Tribbles family pseudokinase, MEK1, MAPK/ERK kinase 1, Janus kinase, Protein Kinases

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::347bb969af6393a9dbd36972faefed95Test
https://doi.org/10.1016/j.jbc.2021.100705Test

المؤلفون: Maria Loiarro, Roberto Furlan, Elisabetta Volpe, Chiara Maiorino, Vito Ruggiero, Claudio Sette, Luca Battistini, Grazia Gallo

المصدر: Journal of Biological Chemistry. 288:30210-30222

مصطلحات موضوعية: animal diseases, medicine.disease_cause, Biochemistry, Monocytes, Interleukin-1 Receptor-Associated Kinases, Site-Directed, Toll IL-1 Receptor (TIR) Domain, Settore BIO/16, Mutation, Tumor, NF-kappa B, Signal transducing adaptor protein, hemic and immune systems, Toll-like Receptor (TLR), Signal transduction, Signal Transduction, Protein Structure, Mutation, Missense, chemical and pharmacologic phenomena, Biology, Cell Line, Cell Line, Tumor, medicine, Humans, Molecular Biology, Death domain, HEK 293 cells, Dendritic Cells, HEK293 Cells, Cellular Immune Response, Toll-Like Receptor 2, Protein Multimerization, Toll-Like Receptor 4, Mutagenesis, MyD88, Mutagenesis, Site-Directed, Myeloid Differentiation Factor 88, Protein Structure, Tertiary, Amino Acid Substitution, Cell Biology, biochemical phenomena, metabolism, and nutrition, Molecular biology, TLR2, bacteria, Missense, Tertiary

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a4b800be5ba362dfd5682179b21a1bfTest
https://doi.org/10.1074/jbc.m113.490946Test