نتائج البحث - "Lactate dehydrogenase"

1

Oxidative stress induces Z-DNA-binding protein 1–dependent activation of microglia via mtDNA released from retinal pigment epithelial cells

المؤلفون: Jamal Saada, Ryan J. McAuley, Michela Marcatti, Tony Zifeng Tang, Massoud Motamedi, Bartosz Szczesny

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: NLRP3, nucleotide-binding domain leucine-rich repeat family, pyrin-domain containing 3, MCT3, monocarboxylate transporter 3, genetic structures, microglia, mitochondrial DNA, Retinal Pigment Epithelium, Biochemistry, BrDU, bromodeoxyuridine, 0302 clinical medicine, oxidative stress, 8-oxoG, 8-hydroxy-2′-deoxy-guanosine, AMD, age-related macular degeneration, IL, interleukins, 0303 health sciences, LDH, lactate dehydrogenase, TFAM, mitochondrial transcription factor A, qPCR, quantitative real-time PCR, EVs, extracellular vesicles, RNA-Binding Proteins, IP, immunoprecipitation, RIPK1 and RIPK3, kinases receptor-interacting protein 1 and 3, DNA-Binding Proteins, retinal pigment epithelial, extracellular vesicles, Retinal Pigments, Research Article, MTT assay, 3-[4,5-dimethylthiazol-2-yl]-2,5 diphenyl tetrazolium bromide assay, STING, stimulator of interferon genes, DNA, Mitochondrial, 03 medical and health sciences, ROS, reactive oxygen species, TLR9, Toll like receptor 9, Humans, IFN, interferon, Molecular Biology, 030304 developmental biology, Inflammation, ZBP1, Z-DNA binding protein 1, PLA, proximity ligation assay, IRF3, interferon regulatory factor 3, Epithelial Cells, Cell Biology, eye diseases, GOx, glucose oxidase, nuDNA, nuclear DNA, mtDNA, mitochondrial DNA, RPE, retinal pigment epithelial, CRLBP, cellular retinaldehyde-binding protein 1, cGAS, cyclic GMP-AMP synthase, TBK1, TANK-binding kinase 1, LA-qPCR, long amplicon semiquantitative PCR, sense organs, NTA, Nanoparticle Tracking Analysis, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6155e8a22f65e20ca59d4f81e0fe350eTest
https://doi.org/10.1016/j.jbc.2021.101523Test

2

Metallothionein-III Prevents γ-Ray-induced 8-Oxoguanine Accumulation in Normal and hOGG1-depleted Cells

المؤلفون: In-Youb Chang, Ho Jin You, Mihwa Kim, Yun Sil Lee, Hong-Beum Kim, Myung-Hee Chung, Cha-Kyung Youn, Hyun Ju Cho, Hye Gwang Jeong, Soo-Hyun Kim

المصدر: Journal of Biological Chemistry. 279:34138-34149

مصطلحات موضوعية: Small interfering RNA, Guanine, Blotting, Western, DNA Mutational Analysis, Genetic Vectors, Mutant, Down-Regulation, Nerve Tissue Proteins, Biology, medicine.disease_cause, Biochemistry, Neuroprotection, Antioxidants, Cell Line, DNA Glycosylases, chemistry.chemical_compound, medicine, Humans, Protein Isoforms, Gene Silencing, RNA, Messenger, RNA, Small Interfering, Mutation frequency, Molecular Biology, Neurons, Mutation, L-Lactate Dehydrogenase, Reverse Transcriptase Polymerase Chain Reaction, Dose-Response Relationship, Radiation, DNA, Cell Biology, Fibroblasts, Molecular biology, Metallothionein 3, 8-Oxoguanine, Oxidative Stress, DNA-Formamidopyrimidine Glycosylase, chemistry, Gamma Rays, DNA glycosylase, Oxidative stress, DNA Damage

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b3657f9487dd888819aae0eb809d01bTest
https://doi.org/10.1074/jbc.m402530200Test

3

Low Energy Visible Light Induces Reactive Oxygen Species Generation and Stimulates an Increase of Intracellular Calcium Concentration in Cardiac Cells

المؤلفون: Harry Friedmann, Ophra Rickover, Rachel Lubart, Vladimir Shneyvays, Asher Shainberg, Doron Kaplan, Ronit Lavi, Maor Eichler

المصدر: Journal of Biological Chemistry. 278:40917-40922

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2fa288088d586d81d2f8d7ac5fcfcf3Test
https://doi.org/10.1074/jbc.m303034200Test

4

Induction of Glia Maturation Factor-β in Proximal Tubular Cells Leads to Vulnerability to Oxidative Injury through the p38 Pathway and Changes in Antioxidant Enzyme Activities

المؤلفون: Takeshi Sugaya, Kousaku Okubo, Hideaki Nakajima, Masaru Horio, Enyu Imai, Masatsugu Hori, Takahito Ito, Masaru Takenaka, Takayuki Hamano, Jun-ya Kaimori

المصدر: Journal of Biological Chemistry. 278:33519-33527

مصطلحات موضوعية: Time Factors, Apoptosis, Kidney, medicine.disease_cause, p38 Mitogen-Activated Protein Kinases, Biochemistry, Antioxidants, Mice, chemistry.chemical_compound, Annexin A5, Coloring Agents, In Situ Hybridization, chemistry.chemical_classification, Microscopy, Confocal, Caspase 3, Angiotensin II, Glutathione peroxidase, Brain, 3T3 Cells, Flow Cytometry, Cell biology, Kidney Tubules, Caspases, Tumor necrosis factor alpha, Mitogen-Activated Protein Kinases, Glia Maturation Factor, Programmed cell death, Cell Survival, Glia maturation factor, Biology, Transfection, Models, Biological, medicine, Animals, Molecular Biology, Glutathione Peroxidase, L-Lactate Dehydrogenase, Superoxide Dismutase, Tumor Necrosis Factor-alpha, Lasers, Hydrogen Peroxide, Cell Biology, Glutathione, Blotting, Northern, Actins, Mice, Inbred C57BL, Oxygen, Oxidative Stress, chemistry, Oxidative stress

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9092bd0a87bab091cfcc450959cab7cTest
https://doi.org/10.1074/jbc.m301552200Test

5

A Newly Established Neuronal ρ-0 Cell Line Highly Susceptible to Oxidative Stress Accumulates Iron and Other Metals

المؤلفون: Hirofumi Sakaguchi, Teruo Mukainaka, Hiroe Toba, Taizen Nakase, Shinji Fushiki, Takuya Saiwaki, Ryuichi Fukuyama, Hiromu Sakurai, Akihiko Nakayama, Mikio Wada

المصدر: Journal of Biological Chemistry. 277:41455-41462

مصطلحات موضوعية: Mitochondrial DNA, Cellular respiration, Cell, Cell Biology, Biology, medicine.disease_cause, Biochemistry, Molecular biology, Deferoxamine, chemistry.chemical_compound, medicine.anatomical_structure, chemistry, Cell culture, Lactate dehydrogenase, medicine, Glycolysis, Molecular Biology, Oxidative stress, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::59e264ed9ab7ac4446e858dfd4f8ed88Test
https://doi.org/10.1074/jbc.m204176200Test

6

Oxidative Damage of Cardiomyocytes Is Limited by Extracellular Regulated Kinases 1/2-mediated Induction of Cyclooxygenase-2

المؤلفون: Desmond J. Fitzgerald, Sharon R. Adderley

المصدر: Journal of Biological Chemistry. 274:5038-5046

مصطلحات موضوعية: MAPK/ERK pathway, Free Radicals, Prostacyclin, Pharmacology, medicine.disease_cause, Biochemistry, chemistry.chemical_compound, Lactate dehydrogenase, medicine, Animals, Myocyte, Doxorubicin, Iloprost, Rats, Wistar, Molecular Biology, Cells, Cultured, Mitogen-Activated Protein Kinase 3, Base Sequence, biology, Kinase, Myocardium, NF-kappa B, DNA, Hydrogen Peroxide, Cell Biology, Molecular biology, Rats, Isoenzymes, Transcription Factor AP-1, Oxidative Stress, Animals, Newborn, chemistry, Cyclooxygenase 2, Prostaglandin-Endoperoxide Synthases, Enzyme Induction, Calcium-Calmodulin-Dependent Protein Kinases, biology.protein, Cyclooxygenase, Mitogen-Activated Protein Kinases, Oxidative stress, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72b545766d36a3152618f59eef7f416aTest
https://doi.org/10.1074/jbc.274.8.5038Test

7

The Small Heat-shock Protein IbpB from Escherichia coli Stabilizes Stress-denatured Proteins for Subsequent Refolding by a Multichaperone Network

المؤلفون: Pierre Goloubinoff, Johannes Buchner, Lea Veinger, Sophia Diamant

المصدر: Journal of Biological Chemistry. 273:11032-11037

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7836c8ae1ed945677da3296c46723f49Test
https://doi.org/10.1074/jbc.273.18.11032Test

8

Down-regulation of P4501A1 and P4501A2 mRNA expression in isolated hepatocytes by oxidative stress

المؤلفون: C W Barker, D S Pasco, John Fagan

المصدر: Journal of Biological Chemistry. 269:3985-3990

مصطلحات موضوعية: Messenger RNA, Cytochrome P450, Dehydrogenase, Cell Biology, Biology, medicine.disease_cause, Biochemistry, Molecular biology, chemistry.chemical_compound, medicine.anatomical_structure, chemistry, Downregulation and upregulation, Transcription (biology), Hepatocyte, Lactate dehydrogenase, medicine, biology.protein, Molecular Biology, Oxidative stress

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::953bcc3d3019fe3ce37827edf6b76d20Test
https://doi.org/10.1016/s0021-9258Test(17)41731-5

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