التفاصيل البيبلوغرافية
| العنوان: |
Bone Density in Adolescents and Young Adults with Autism Spectrum Disorders. |
| المؤلفون: |
Ekhlaspour, Laya1 lekhlaspour@mgh.harvard.edu, Baskaran, Charumathi1 cbaskaran@mgh.harvard.edu, Campoverde, Karen2 kcampoverdereyes@partners.org, Sokoloff, Natalia2 natalia.cano@gmail.com, Neumeyer, Ann3 aneumeyer@mgh.harvard.edu, Misra, Madhusmita1 mmisra@partners.org |
| المصدر: |
Journal of Autism & Developmental Disorders. Nov2016, Vol. 46 Issue 11, p3387-3391. 5p. 2 Charts. |
| مصطلحات موضوعية: |
*RISK factors of fractures, *AUTISM, *STATISTICAL correlation, *MULTIVARIATE analysis, *PROBABILITY theory, *BONE density, *BODY mass index, *DATA analysis software, *PHOTON absorptiometry, *ADOLESCENCE |
| مستخلص: |
Patients with autism spectrum disorder (ASD) are at increased risk for fracture, and peri-pubertal boys with ASD have lower bone mineral density (BMD) than controls. Data are lacking regarding BMD in older adolescents with ASD. We compared BMD using dual-energy X-ray absorptiometry in 9 adolescents/young adults with ASD against 9 typically developing matched controls. Patients with ASD and controls were excluded if they had other underlying conditions that may affect bone. Compared to controls, patients with ASD had (i) lower femoral neck and hip BMD Z-scores, and (ii) lower spine, femoral neck and hip height adjusted BMD Z-scores even after controlling for BMI. Understanding the underlying pathophysiology will be key to developing therapies to improve BMD and reduce fracture risk. [ABSTRACT FROM AUTHOR] |
| قاعدة البيانات: |
Academic Search Index |
