Quantitative analysis of MRI-guided radiotherapy treatment process time for tumor real-time gating efficiency

التفاصيل البيبلوغرافية
العنوان: Quantitative analysis of MRI-guided radiotherapy treatment process time for tumor real-time gating efficiency
المؤلفون: Veronica Pollutri, Giuditta Chiloiro, Viola De Luca, Vincenzo Valentini, Luca Indovina, Davide Cusumano, C. Votta, Luca Boldrini, Marco Valerio Antonelli, F. Catucci, Angela Romano, Lorenzo Placidi
المصدر: Journal of Applied Clinical Medical Physics
سنة النشر: 2020
مصطلحات موضوعية: Breathing control, gating efficiency, medicine.medical_treatment, Radiotherapy Planning, MR‐guided radiotherapy, Gating, MR-guided radiotherapy, 030218 nuclear medicine & medical imaging, Breath Holding, 03 medical and health sciences, Computer-Assisted, 0302 clinical medicine, Neoplasms, Medicine, Humans, Radiation Oncology Physics, Radiology, Nuclear Medicine and imaging, Instrumentation, Settore MED/36 - DIAGNOSTICA PER IMMAGINI E RADIOTERAPIA, Radiation, Radiotherapy, business.industry, Radiotherapy Planning, Computer-Assisted, Treatment process, Continuous monitoring, Magnetic Resonance Imaging, Radiation therapy, Time gating, Image-Guided, time analysis, 030220 oncology & carcinogenesis, Particle Accelerators, business, Nuclear medicine, Mri guided radiotherapy, Quantitative analysis (chemistry), Radiotherapy, Image-Guided
الوصف: Purpose Magnetic Resonance‐guided radiotherapy (MRgRT) systems allow continuous monitoring of therapy volumes during treatment delivery and personalized respiratory gating approaches. Treatment length may therefore be significantly affected by patient’s compliance and breathing control. We quantitatively analyzed treatment process time efficiency (TE) using data obtained from real‐world patient treatment logs to optimize MRgRT delivery settings. Methods Data corresponding to the first 100 patients treated with a low T hybrid MRI‐Linac system, both in free breathing (FB) and in breath hold inspiration (BHI) were collected. TE has been computed as the percentage difference of the actual single fraction’s total treatment time and the predicted treatment process time, as computed by the TPS during plan optimization. Differences between the scheduled and actual treatment room occupancy time were also evaluated. Finally, possible correlations with planning, delivery and clinical parameters with TE were also investigated. Results Nine hundred and nineteen treatment fractions were evaluated. TE difference between BHI and FB patients’ groups was statistically significant and the mean TE were 42.4%, and −0.5% respectively. No correlation was found with TE for BHI and FB groups. Planning, delivering and clinical parameters classified BHI and FB groups, but no correlation with TE was found. Conclusion The use of BHI gating technique can increase the treatment process time significantly. BHI technique could be not always an adequate delivery technique to optimize the treatment process time. Further gating techniques should be considered to improve the use of MRgRT.
تدمد: 1526-9914
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a06c26e16405bb055b5ae52bd0eed9c4Test
https://pubmed.ncbi.nlm.nih.gov/33089954Test
حقوق: OPEN
رقم الانضمام: edsair.doi.dedup.....a06c26e16405bb055b5ae52bd0eed9c4
قاعدة البيانات: OpenAIRE