دورية أكاديمية
Genome-wide association study for the free amino acid and nucleotide components of breast meat in an F2 crossbred chicken population
| العنوان: | Genome-wide association study for the free amino acid and nucleotide components of breast meat in an F2 crossbred chicken population |
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| المؤلفون: | Minjun Kim, Eunjin Cho, Jean Pierre Munyaneza, Thisarani Kalhari Ediriweera, Jihye Cha, Daehyeok Jin, Sunghyun Cho, Jun Heon Lee |
| المصدر: | Journal of Animal Science and Technology, Vol 65, Iss 1, Pp 57-68 (2023) |
| بيانات النشر: | Korean Society of Animal Sciences and Technology, 2023. |
| سنة النشر: | 2023 |
| المجموعة: | LCC:Animal culture |
| مصطلحات موضوعية: | Chicken, Breast meat, Free amino acids, Nucleotides, Genome-wide association study, Animal culture, SF1-1100 |
| الوصف: | Flavor is an important sensory trait of chicken meat. The free amino acid (FAA) and nucleotide (NT) components of meat are major factors affecting meat flavor during the cooking process. As a genetic approach to improve meat flavor, we performed a genome-wide association study (GWAS) to identify the potential candidate genes related to the FAA and NT components of chicken breast meat. Measurements of FAA and NT components were recorded at the age of 10 weeks from 764 and 767 birds, respectively, using a White leghorn and Yeonsan ogye crossbred F2 chicken population. For genotyping, we used 60K Illumina single-nucleotide polymorphism (SNP) chips. We found a total of nine significant SNPs for five FAA traits (arginine, glycine, lysine, threonine content, and the essential FAAs and one NT trait (inosine content), and six significant genomic regions were identified, including three regions shared among the essential FAAs, arginine, and inosine content traits. A list of potential candidate genes in significant genomic regions was detected, including the KCNRG, KCNIP4, HOXA3, THSD7B, and MMUT genes. The essential FAAs had significant gene regions the same as arginine. The genes related to arginine content were involved in nitric oxide metabolism, while the inosine content was possibly affected by insulin activity. Moreover, the threonine content could be related to methylmalonyl-CoA mutase. The genes and SNPs identified in this study might be useful markers in chicken selection and breeding for chicken meat flavor. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2672-0191 2055-0391 |
| العلاقة: | http://www.ejast.org/archive/view_article?doi=10.5187/jast.2022.e96Test; https://doaj.org/toc/2672-0191Test; https://doaj.org/toc/2055-0391Test |
| DOI: | 10.5187/jast.2022.e96 |
| الوصول الحر: | https://doaj.org/article/a798046ea7d64f00a1ab073bfca28036Test |
| رقم الانضمام: | edsdoj.798046ea7d64f00a1ab073bfca28036 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 26720191 20550391 |
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| DOI: | 10.5187/jast.2022.e96 |