نتائج البحث

1

Hepatitis B virus reactivation in cancer patients with positive Hepatitis B surface antigen undergoing PD-1 inhibition

المؤلفون: Yuxiang Ma, Ming Zhao, Yan Huang, Xiuyu Cai, Wenqi Jiang, Yixin Zhou, Hongyun Zhao, Chen Chen, Xiaoshi Zhang, Wenfeng Fang, Zuan Lin, Shaodong Hong, Li Zhang, Xuanye Zhang, Rui-Hua Xu, Yunpeng Yang, Bei Zhang

المصدر: Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-10 (2019)
Journal for Immunotherapy of Cancer

مصطلحات موضوعية: Male, 0301 basic medicine, Cancer Research, HBsAg, medicine.medical_treatment, Programmed Cell Death 1 Receptor, medicine.disease_cause, Gastroenterology, B7-H1 Antigen, Antineoplastic Agents, Immunological, 0302 clinical medicine, Risk Factors, Neoplasms, PD-1, Immunology and Allergy, Cancer, biology, Checkpoint, virus diseases, Middle Aged, Reactivation, Hepatitis B, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, virology, Oncology, 030220 oncology & carcinogenesis, Molecular Medicine, Female, Immunotherapy, Safety, Antibody, liver disease, Research Article, Adult, PD-L1, medicine.medical_specialty, Hepatitis B virus, Immunology, Antiviral Agents, lcsh:RC254-282, Young Adult, 03 medical and health sciences, Internal medicine, Biomarkers, Tumor, medicine, Humans, Retrospective Studies, Pharmacology, Hepatitis, Chemotherapy, Hepatitis B Surface Antigens, business.industry, medicine.disease, digestive system diseases, 030104 developmental biology, Alanine transaminase, Commentary, biology.protein, Virus Activation, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ea49583d5b5c254a92def2d9371d965Test
http://link.springer.com/article/10.1186/s40425-019-0808-5Test

2

Secondary resistance to immunotherapy associated with β-catenin pathway activation or PTEN loss in metastatic melanoma

المؤلفون: Stefani Spranger, Lauren L. Ritterhouse, Jonathan A. Trujillo, Jason J. Luke, Karen Matijevich, Jeremy P. Segal, Thomas F. Gajewski, Yuanyuan Zha

المصدر: Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-11 (2019)
Journal for Immunotherapy of Cancer

مصطلحات موضوعية: 0301 basic medicine, Male, Cancer Research, medicine.medical_treatment, Programmed Cell Death 1 Receptor, 0302 clinical medicine, Antineoplastic Agents, Immunological, PTEN-loss, Immunology and Allergy, β-Catenin activation, CTLA-4 Antigen, Melanoma, beta Catenin, Peptide vaccine, biology, High-Throughput Nucleotide Sequencing, Immune exclusion, Middle Aged, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Interleukin-12, 3. Good health, medicine.anatomical_structure, Nivolumab, Oncology, 030220 oncology & carcinogenesis, Molecular Medicine, Immunotherapy, Antibody, Research Article, Signal Transduction, Adult, Metastatic melanoma, T cell, Immunology, Secondary resistance, Cancer Vaccines, lcsh:RC254-282, 03 medical and health sciences, Young Adult, medicine, PTEN, Humans, Pharmacology, business.industry, PTEN Phosphohydrolase, Ipilimumab, Blockade, 030104 developmental biology, Drug Resistance, Neoplasm, Catenin, biology.protein, Cancer research, Next-generation sequencing, business, Transcriptome, Immune checkpoint blockade

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4b7cfeb16493056edddd6f47f459901Test
http://link.springer.com/article/10.1186/s40425-019-0780-0Test

3

Intratumoral talimogene laherparepvec injection with concurrent preoperative radiation in patients with locally advanced soft-tissue sarcoma of the trunk and extremities: phase IB/II trial

المصدر: Journal for Immunotherapy of Cancer
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 7 (2021)

مصطلحات موضوعية: 0301 basic medicine, Male, Cancer Research, medicine.medical_treatment, Herpesvirus 1, Human, 0302 clinical medicine, Antineoplastic Agents, Immunological, Immunology and Allergy, Medicine, RC254-282, Tumor Biomarkers, Aged, 80 and over, Oncolytic Virotherapy, medicine.diagnostic_test, Soft tissue sarcoma, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Sarcoma, Middle Aged, Oncology, 030220 oncology & carcinogenesis, Preoperative Period, Molecular Medicine, Female, Radiology, Talimogene laherparepvec, Adult, medicine.medical_specialty, Immunology, 03 medical and health sciences, Biopsy, Humans, Clinical Trials, Aged, Pharmacology, Myxoid liposarcoma, Biological Products, Radiotherapy, business.industry, Phase II as Topic, Extremities, medicine.disease, Oncolytic virus, Clinical trial, Radiation therapy, Oncolytic and Local Immunotherapy, 030104 developmental biology, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10e946535cd1aa54618adf1d03683614Test
https://pubmed.ncbi.nlm.nih.gov/34330766Test

4

Genomic profiling of advanced cervical cancer to predict response to programmed death-1 inhibitor combination therapy: a secondary analysis of the CLAP trial

المؤلفون: Chunyan Lan, Zhimin Liu, Dongqin Zhu, Fan Yang, Minjun He, Hongyu Peng, Chongjie Tong, Xiao-Long Zhang, Xin Huang, Jiani C. Yin, Junli Zhang, Yang Shao

المصدر: Journal for ImmunoTherapy of Cancer, Vol 9, Iss 5 (2021)
Journal for Immunotherapy of Cancer

مصطلحات موضوعية: 0301 basic medicine, Oncology, Cancer Research, Time Factors, Pyridines, medicine.medical_treatment, Programmed Cell Death 1 Receptor, Phases of clinical research, Uterine Cervical Neoplasms, chemistry.chemical_compound, 0302 clinical medicine, Risk Factors, Immunotherapy Biomarkers, Antineoplastic Combined Chemotherapy Protocols, Immunology and Allergy, Apatinib, Immune Checkpoint Inhibitors, RC254-282, Cervical cancer, biology, medicine.diagnostic_test, High-Throughput Nucleotide Sequencing, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Middle Aged, Progression-Free Survival, drug therapy, Gene Expression Regulation, Neoplastic, 030220 oncology & carcinogenesis, Disease Progression, Molecular Medicine, Female, immunotherapy, Signal Transduction, Adult, medicine.medical_specialty, Combination therapy, Immunology, Antibodies, Monoclonal, Humanized, Risk Assessment, 03 medical and health sciences, Predictive Value of Tests, Internal medicine, Biopsy, medicine, PTEN, Humans, Protein Kinase Inhibitors, PI3K/AKT/mTOR pathway, Aged, combination, Pharmacology, business.industry, Gene Expression Profiling, Immunotherapy, medicine.disease, 030104 developmental biology, chemistry, genetic markers, biology.protein, business, Transcriptome

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f04b4bdd5597fc08e7efbeb45dcf1695Test
https://jitc.bmj.com/content/9/5/e002223.fullTest

5

Predicting anti-PD-1 responders in malignant melanoma from the frequency of S100A9+ monocytes in the blood

المؤلفون: Soudabeh Rad Pour, Xavier Martinez Demorentin, Yago Pico de Coaña, David Gomez-Cabrero, Maria Wolodarski, Johan Hansson, Manjula Thimma, Rolf Kiessling, Jeroen Melief, Jesper Tegnér

المصدر: Journal for ImmunoTherapy of Cancer, Vol 9, Iss 5 (2021)
Journal for Immunotherapy of Cancer

مصطلحات موضوعية: Male, 0301 basic medicine, Oncology, Cancer Research, Skin Neoplasms, Time Factors, medicine.medical_treatment, Programmed Cell Death 1 Receptor, active, Monocytes, 0302 clinical medicine, Immunology and Allergy, RNA-Seq, Immune Checkpoint Inhibitors, Melanoma, RC254-282, Aged, 80 and over, Clinical/Translational Cancer Immunotherapy, medicine.diagnostic_test, CD4-CD8 ratio, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Middle Aged, Flow Cytometry, Nivolumab, Treatment Outcome, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Molecular Medicine, Female, immunotherapy, Single-Cell Analysis, Adult, medicine.medical_specialty, Immunology, therapies, investigational, Peripheral blood mononuclear cell, Flow cytometry, 03 medical and health sciences, Predictive Value of Tests, Internal medicine, gene expression profiling, medicine, Calgranulin B, Humans, Aged, Sweden, Pharmacology, business.industry, Monocyte, Immunotherapy, medicine.disease, Blockade, 030104 developmental biology, business, Checkpoint Blockade Immunotherapy

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dce267ed6b6145ca7733d8384ece8faTest
https://jitc.bmj.com/content/9/5/e002171.fullTest

6

Tumor hypoxia is associated with resistance to PD-1 blockade in squamous cell carcinoma of the head and neck

المؤلفون: Angen Liu, Robert L. Ferris, Dan P. Zandberg, Ashley V. Menk, Maria A. Velez, Greg M. Delgoffe, Kristin DePeaux, Daniel P. Normolle

المصدر: Journal for Immunotherapy of Cancer
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 5 (2021)

مصطلحات موضوعية: 0301 basic medicine, lymphocytes, Male, Cancer Research, medicine.medical_treatment, T-Lymphocytes, Programmed Cell Death 1 Receptor, 0302 clinical medicine, Antineoplastic Agents, Immunological, Tumor Microenvironment, Immunology and Allergy, Immune Checkpoint Inhibitors, RC254-282, Clinical/Translational Cancer Immunotherapy, Aged, 80 and over, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Immunosuppression, Middle Aged, Progression-Free Survival, Tumor Burden, Oncology, 030220 oncology & carcinogenesis, Molecular Medicine, Female, immunotherapy, medicine.symptom, metabolic networks and pathways, Oxidation-Reduction, Signal Transduction, Adult, Immunology, 03 medical and health sciences, head and neck neoplasms, Lymphocytes, Tumor-Infiltrating, Cell Line, Tumor, medicine, Pimonidazole, Animals, Humans, Progression-free survival, Aged, Retrospective Studies, Pharmacology, Tumor microenvironment, Tumor hypoxia, business.industry, Squamous Cell Carcinoma of Head and Neck, Immunotherapy, Hypoxia (medical), tumor-infiltrating, Xenograft Model Antitumor Assays, Mice, Inbred C57BL, 030104 developmental biology, Drug Resistance, Neoplasm, Cancer research, Tumor Hypoxia, business, Energy Metabolism, CD8

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90a738a335f0dbb51e76431215797d38Test
http://europepmc.org/articles/PMC8126285Test

7

Avelumab as second-line therapy for metastatic, platinum-treated urothelial carcinoma in the phase Ib JAVELIN Solid Tumor study: 2-year updated efficacy and safety analysis

المؤلفون: Jeffrey R. Infante, Patrick Schöffski, Michael S. Gordon, Alain Ravaud, Manish Agrawal, John Allan Ellerton, Juliane Manitz, Manish R. Patel, Mary Ruisi, Andrea B. Apolo, Matthew H. Taylor, Luc Dirix, Ding Wang, Keun Wook Lee, Raid Aljumaily, Gregory Pennock, Theodore Gourdin, J.L. Gulley

المصدر: Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Journal for Immunotherapy of Cancer

مصطلحات موضوعية: 0301 basic medicine, Adult, Male, Cancer Research, medicine.medical_specialty, Metastatic Urothelial Carcinoma, Immunology, Antibodies, Monoclonal, Humanized, Gastroenterology, B7-H1 Antigen, programmed cell death 1 receptor, Avelumab, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Programmed cell death 1, Antineoplastic Combined Chemotherapy Protocols, Immunology and Allergy, Medicine, Humans, Until Disease Progression, Solid tumor, RC254-282, Urothelial carcinoma, Aged, Platinum, Pharmacology, Aged, 80 and over, Clinical/Translational Cancer Immunotherapy, Second-line therapy, Carcinoma, Transitional Cell, biology, clinical trials as topic, business.industry, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Middle Aged, 030104 developmental biology, Oncology, 030220 oncology & carcinogenesis, Toxicity, biology.protein, Molecular Medicine, Female, business, urinary bladder neoplasms, medicine.drug

وصف الملف: Print

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b5b9fa96546aac04d870e76ec58182cTest
https://jitc.bmj.com/content/8/2/e001246.fullTest

8

Enhancing clinical and immunological effects of anti-PD-1 with belapectin, a galectin-3 inhibitor

المصدر: Journal for ImmunoTherapy of Cancer, Vol 9, Iss 4 (2021)
Journal for Immunotherapy of Cancer

مصطلحات موضوعية: 0301 basic medicine, Oncology, Male, Cancer Research, Time Factors, medicine.medical_treatment, Programmed Cell Death 1 Receptor, Pembrolizumab, 0302 clinical medicine, Antineoplastic Combined Chemotherapy Protocols, Immunology and Allergy, Immune Checkpoint Inhibitors, T-lymphocytes, RC254-282, Clinical/Translational Cancer Immunotherapy, clinical trials as topic, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Blood Proteins, Middle Aged, Treatment Outcome, Head and Neck Neoplasms, 030220 oncology & carcinogenesis, immunohistochemistry, Molecular Medicine, Pectins, Female, Multiple Myeloma, Adult, medicine.medical_specialty, Galectins, Immunology, Antibodies, Monoclonal, Humanized, 03 medical and health sciences, Memory T Cells, Immune system, Internal medicine, medicine, Humans, Aged, Pharmacology, Autoimmune disease, business.industry, Squamous Cell Carcinoma of Head and Neck, Myeloid-Derived Suppressor Cells, Immunotherapy, medicine.disease, Head and neck squamous-cell carcinoma, Blockade, 030104 developmental biology, Myeloid-derived Suppressor Cell, business, CD8

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a1c844347afeb00988b18adab8210aeTest
https://jitc.bmj.com/content/9/4/e002371.fullTest

9

Tumor DNA methylation profiles correlate with response to anti-PD-1 immune checkpoint inhibitor monotherapy in sarcoma patients

المؤلفون: Stefan Traint, Sebastian Bauer, Thomas Brodowicz, Gerwin Heller, Katharina Feldmann, Julia Furtner, Gabriele Amann, Rainer Hamacher, Teresa Hatziioannou, Iris M. Noebauer-Huhmann, Leonhard Müllauer, Wolfgang Lamm, Angelika M. Starzer, Erwin Tomasich, Hans-Ulrich Schildhaus, Anna S. Berghoff, Matthias Preusser

المصدر: Journal for ImmunoTherapy of Cancer, Vol 9, Iss 3 (2021)
Journal for Immunotherapy of Cancer

مصطلحات موضوعية: Epigenomics, Male, 0301 basic medicine, Cancer Research, Time Factors, sarcoma, medicine.medical_treatment, Programmed Cell Death 1 Receptor, Medizin, biostatistics, Soft Tissue Neoplasms, Epigenome, 0302 clinical medicine, Germany, Immunotherapy Biomarkers, Tumor Microenvironment, Immunology and Allergy, Immune Checkpoint Inhibitors, RC254-282, Aged, 80 and over, Osteosarcoma, Predictive marker, FOXP3, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Methylation, Middle Aged, Progression-Free Survival, Oncology, CpG site, Austria, 030220 oncology & carcinogenesis, DNA methylation, Molecular Medicine, Female, immunotherapy, Sarcoma, Signal Transduction, Adult, tumor, Immunology, Bone Neoplasms, Young Adult, 03 medical and health sciences, Lymphocytes, Tumor-Infiltrating, medicine, Humans, Aged, Retrospective Studies, Pharmacology, business.industry, biomarkers, Immunotherapy, DNA Methylation, medicine.disease, Immune checkpoint, 030104 developmental biology, Cancer research, CpG Islands, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::757e63d071fac70057305b1163d6f22aTest
https://jitc.bmj.com/content/9/3/e001458.fullTest

10

Copy number loss in granzyme genes confers resistance to immune checkpoint inhibitor in nasopharyngeal carcinoma

المؤلفون: Yunpeng Yang, Yang Zhang, Hua Bao, Xue Wu, Wanxiangfu Tang, Shaodong Hong, Wenfeng Fang, Ao Wang, Yang Shao, Li Zhang, Yan Huang, Qingguang Lin, Yuxiang Ma, Hongyun Zhao, Xi Chen

المصدر: Journal for ImmunoTherapy of Cancer, Vol 9, Iss 3 (2021)
Journal for Immunotherapy of Cancer

مصطلحات موضوعية: 0301 basic medicine, Oncology, Male, Cancer Research, Time Factors, medicine.medical_treatment, Programmed Cell Death 1 Receptor, Gene Dosage, Granzymes, Metastasis, 0302 clinical medicine, Immunotherapy Biomarkers, Immunology and Allergy, Immune Checkpoint Inhibitors, RC254-282, Nasopharyngeal Carcinoma, biology, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Middle Aged, Progression-Free Survival, 030220 oncology & carcinogenesis, Disease Progression, Molecular Medicine, Female, immunotherapy, Adult, medicine.medical_specialty, DNA Copy Number Variations, Immunology, Antibodies, Monoclonal, Humanized, GZMB, 03 medical and health sciences, Young Adult, Clinical Trials, Phase II as Topic, head and neck neoplasms, Internal medicine, medicine, Biomarkers, Tumor, Humans, Aged, Retrospective Studies, Pharmacology, Chemotherapy, business.industry, Nasopharyngeal Neoplasms, Immunotherapy, medicine.disease, Granzyme B, 030104 developmental biology, Granzyme, Nasopharyngeal carcinoma, Drug Resistance, Neoplasm, tumor biomarkers, biology.protein, business, Granzyme H

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3e933c8331f27c24226e77838695cf3Test
https://jitc.bmj.com/content/9/3/e002014.fullTest

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