نتائج البحث

1

Real-world insights on preferred treatments for steroid-refractory immune checkpoint inhibitor-induced pneumonitis

المؤلفون: Gatti-Mays, Margaret, Gulley, James L

المصدر: Journal for ImmunoTherapy of Cancer, Vol 9, Iss 2 (2021)
Journal for Immunotherapy of Cancer

مصطلحات موضوعية: 0301 basic medicine, Oncology, Cancer Research, medicine.medical_specialty, Immune checkpoint inhibitors, medicine.medical_treatment, Immunology, programmed cell death 1 receptor, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, polycyclic compounds, medicine, Immunology and Allergy, Adverse effect, RC254-282, Pneumonitis, Pharmacology, business.industry, Incidence (epidemiology), Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Immunotherapy, Programmed Cell Death 1 Receptor, medicine.disease, Clinical trial, Editorial, 030104 developmental biology, 030220 oncology & carcinogenesis, Molecular Medicine, immunotherapy, Steroid refractory, business, guidelines as topic, hormones, hormone substitutes, and hormone antagonists

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c649cef396578a61a9a2f9dc3a664994Test
https://jitc.bmj.com/content/9/2/e002252.fullTest

2

Hepatitis B virus reactivation in cancer patients with positive Hepatitis B surface antigen undergoing PD-1 inhibition

المؤلفون: Yuxiang Ma, Ming Zhao, Yan Huang, Xiuyu Cai, Wenqi Jiang, Yixin Zhou, Hongyun Zhao, Chen Chen, Xiaoshi Zhang, Wenfeng Fang, Zuan Lin, Shaodong Hong, Li Zhang, Xuanye Zhang, Rui-Hua Xu, Yunpeng Yang, Bei Zhang

المصدر: Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-10 (2019)
Journal for Immunotherapy of Cancer

مصطلحات موضوعية: Male, 0301 basic medicine, Cancer Research, HBsAg, medicine.medical_treatment, Programmed Cell Death 1 Receptor, medicine.disease_cause, Gastroenterology, B7-H1 Antigen, Antineoplastic Agents, Immunological, 0302 clinical medicine, Risk Factors, Neoplasms, PD-1, Immunology and Allergy, Cancer, biology, Checkpoint, virus diseases, Middle Aged, Reactivation, Hepatitis B, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, virology, Oncology, 030220 oncology & carcinogenesis, Molecular Medicine, Female, Immunotherapy, Safety, Antibody, liver disease, Research Article, Adult, PD-L1, medicine.medical_specialty, Hepatitis B virus, Immunology, Antiviral Agents, lcsh:RC254-282, Young Adult, 03 medical and health sciences, Internal medicine, Biomarkers, Tumor, medicine, Humans, Retrospective Studies, Pharmacology, Hepatitis, Chemotherapy, Hepatitis B Surface Antigens, business.industry, medicine.disease, digestive system diseases, 030104 developmental biology, Alanine transaminase, Commentary, biology.protein, Virus Activation, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ea49583d5b5c254a92def2d9371d965Test
http://link.springer.com/article/10.1186/s40425-019-0808-5Test

3

Moving forward to address key unanswered questions on targeting PD-1/PD-L1 in cancer: limitations in preclinical models and the need to incorporate human modifying factors

المؤلفون: William J. Murphy, Catherine T. Le

المصدر: Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-5 (2019)
Journal for immunotherapy of cancer, vol 7, iss 1
Journal for Immunotherapy of Cancer

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Exhaustion, Cell, Programmed Cell Death 1 Receptor, Drug Evaluation, Preclinical, B7-H1 Antigen, Mice, Antineoplastic Agents, Immunological, 0302 clinical medicine, T-cell, Neoplasms, PD-1, Immunology and Allergy, 2.1 Biological and endogenous factors, Molecular Targeted Therapy, Aetiology, Cancer, biology, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Preclinical, medicine.anatomical_structure, Immunological, Oncology, 5.1 Pharmaceuticals, Priming, 030220 oncology & carcinogenesis, Disease Progression, Molecular Medicine, Development of treatments and therapeutic interventions, Signal Transduction, PD-L1, Cell type, T cell, Immunology, Antineoplastic Agents, lcsh:RC254-282, 03 medical and health sciences, Immune checkpoint inhibitors, Immune system, Rare Diseases, medicine, Animals, Humans, Pharmacology, business.industry, Animal, Xenograft Model Antitumor Assays, Immune checkpoint, Blockade, Disease Models, Animal, 030104 developmental biology, Orphan Drug, Good Health and Well Being, Preclinical modeling, Tumor progression, Disease Models, Commentary, biology.protein, Drug Evaluation, business, Neuroscience

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96ff35d61f1bd5b87f50f39a1beb34e6Test
http://link.springer.com/article/10.1186/s40425-019-0789-4Test

4

Secondary resistance to immunotherapy associated with β-catenin pathway activation or PTEN loss in metastatic melanoma

المؤلفون: Stefani Spranger, Lauren L. Ritterhouse, Jonathan A. Trujillo, Jason J. Luke, Karen Matijevich, Jeremy P. Segal, Thomas F. Gajewski, Yuanyuan Zha

المصدر: Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-11 (2019)
Journal for Immunotherapy of Cancer

مصطلحات موضوعية: 0301 basic medicine, Male, Cancer Research, medicine.medical_treatment, Programmed Cell Death 1 Receptor, 0302 clinical medicine, Antineoplastic Agents, Immunological, PTEN-loss, Immunology and Allergy, β-Catenin activation, CTLA-4 Antigen, Melanoma, beta Catenin, Peptide vaccine, biology, High-Throughput Nucleotide Sequencing, Immune exclusion, Middle Aged, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Interleukin-12, 3. Good health, medicine.anatomical_structure, Nivolumab, Oncology, 030220 oncology & carcinogenesis, Molecular Medicine, Immunotherapy, Antibody, Research Article, Signal Transduction, Adult, Metastatic melanoma, T cell, Immunology, Secondary resistance, Cancer Vaccines, lcsh:RC254-282, 03 medical and health sciences, Young Adult, medicine, PTEN, Humans, Pharmacology, business.industry, PTEN Phosphohydrolase, Ipilimumab, Blockade, 030104 developmental biology, Drug Resistance, Neoplasm, Catenin, biology.protein, Cancer research, Next-generation sequencing, business, Transcriptome, Immune checkpoint blockade

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4b7cfeb16493056edddd6f47f459901Test
http://link.springer.com/article/10.1186/s40425-019-0780-0Test

5

Peritumoral administration of DRibbles-pulsed antigen-presenting cells enhances the antitumor efficacy of anti-GITR and anti-PD-1 antibodies via an antigen presenting independent mechanism

المؤلفون: Hong-Ming Hu, Jaina Patel, Catherine Dinh, Zhifa Wen, Zhihua Cui

المصدر: Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-18 (2019)
Journal for Immunotherapy of Cancer

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Lung Neoplasms, T-Lymphocytes, Programmed Cell Death 1 Receptor, Priming (immunology), Dendritic cells, 0302 clinical medicine, Phagosomes, PD-1, Immunology and Allergy, Medicine, Antigen Presentation, Mice, Inbred BALB C, Peritumoral injection, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, medicine.anatomical_structure, Oncology, Tumor microenvironment, 030220 oncology & carcinogenesis, Cytokines, Molecular Medicine, Research Article, T cell, Immunology, Antigen presentation, Antigen-Presenting Cells, Bone Marrow Cells, lcsh:RC254-282, Antibodies, 03 medical and health sciences, Lymphocytes, Tumor-Infiltrating, Immune system, Antigen, Antigens, Neoplasm, Cell Line, Tumor, Glucocorticoid-Induced TNFR-Related Protein, Antigen presenting cells, Animals, GITR, Antigen-presenting cell, Pharmacology, business.industry, Mice, Inbred C57BL, Pancreatic Neoplasms, 030104 developmental biology, Cancer research, Cytokine secretion, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::479cdec7fcc9de373aff0d71fd2fcb2cTest
http://link.springer.com/article/10.1186/s40425-019-0786-7Test

6

Niclosamide, an antihelmintic drug, enhances efficacy of PD-1/PD-L1 immune checkpoint blockade in non-small cell lung cancer

المؤلفون: Fan Luo, Qi Xiang Rong, Min Luo, Hong Zhang, Zhen Chen, Hong Yun Zhao, Liwu Fu, Fang Wang

المصدر: Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-13 (2019)
Journal for Immunotherapy of Cancer

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Lung Neoplasms, medicine.medical_treatment, Programmed Cell Death 1 Receptor, Apoptosis, NSCLC, B7-H1 Antigen, STAT3, Mice, 0302 clinical medicine, Carcinoma, Non-Small-Cell Lung, Tumor Cells, Cultured, Immunology and Allergy, Niclosamide, biology, Antinematodal Agents, Antibodies, Monoclonal, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, medicine.anatomical_structure, Oncology, 030220 oncology & carcinogenesis, Molecular Medicine, Drug Therapy, Combination, Female, Immunotherapy, medicine.drug, Research Article, PD-L1, T cell, Immunology, lcsh:RC254-282, 03 medical and health sciences, medicine, Animals, Humans, Cell Proliferation, Pharmacology, business.industry, Drug Repositioning, Xenograft Model Antitumor Assays, Immune checkpoint, Blockade, Granzyme B, Mice, Inbred C57BL, 030104 developmental biology, Cancer cell, Cancer research, biology.protein, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23b4656e47c8aed420fa4588eebad9c7Test
http://link.springer.com/article/10.1186/s40425-019-0733-7Test

7

ATM/NEMO signaling modulates the expression of PD-L1 following docetaxel chemotherapy in prostate cancer

المؤلفون: Zongren Wang, Wei Ou, Guangyin Zhao, Chengqiang Mo, Zhaoyang Huang, Haiqi Chen, Bin Huang, Junxing Chen, Xinyao Zhang, Wuguo Li, Xueling Zhang, Qiao Su, Lingwu Chen, Lan Shao

المصدر: Journal for ImmunoTherapy of Cancer, Vol 9, Iss 7 (2021)
Journal for Immunotherapy of Cancer

مصطلحات موضوعية: Male, 0301 basic medicine, Cancer Research, medicine.medical_treatment, Docetaxel, B7-H1 Antigen, Mice, Prostate cancer, 0302 clinical medicine, Immunotherapy Biomarkers, Immunology and Allergy, Medicine, RC254-282, Aged, 80 and over, biology, Intracellular Signaling Peptides and Proteins, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Middle Aged, drug therapy, Oncology, 030220 oncology & carcinogenesis, Molecular Medicine, Immunotherapy, immune evation, Signal Transduction, medicine.drug, Programmed cell death, Immunology, Antineoplastic Agents, programmed cell death 1 receptor, 03 medical and health sciences, In vivo, Cell Line, Tumor, PD-L1, Animals, Humans, Aged, Retrospective Studies, combination, Pharmacology, business.industry, Prostatic Neoplasms, medicine.disease, 030104 developmental biology, Cancer cell, Ataxia-telangiectasia, biology.protein, Cancer research, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51cb8a531f6d8ad4fdf5dd4435d73393Test
https://jitc.bmj.com/content/9/7/e001758.fullTest

8

Immunotherapy using IgE or CAR T cells for cancers expressing the tumor antigen SLC3A2

المصدر: Journal for ImmunoTherapy of Cancer, Vol 9, Iss 6 (2021)
Journal for Immunotherapy of Cancer

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Fusion Regulatory Protein 1, Heavy Chain, T cell, medicine.medical_treatment, Immunology, receptors, Immunoglobulin E, 03 medical and health sciences, Mice, 0302 clinical medicine, Antigen, Cancer immunotherapy, medicine, Immunology and Allergy, Animals, Humans, immunoassay, RC254-282, Pharmacology, Clinical/Translational Cancer Immunotherapy, Receptors, Chimeric Antigen, biology, business.industry, antibody specificity, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Immunotherapy, Tumor antigen, Chimeric antigen receptor, cytokines, 030104 developmental biology, medicine.anatomical_structure, Oncology, 030220 oncology & carcinogenesis, chimeric antigen, Cancer research, biology.protein, Molecular Medicine, Antibody, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dac94c519acbe8026949f0b4afe6f254Test
https://jitc.bmj.com/content/9/6/e002140.fullTest

9

Massive PD-L1 and CD8 double positive TILs characterize an immunosuppressive microenvironment with high mutational burden in lung cancer

المؤلفون: Lijia Wu, Yun Chen, Han Wang, Libin Zhang, Yanhui Chen, Hongli Luo, Ying Yang, Henghui Zhang, Yang Wang, Hao Peng, Zheyuan Xu, Li Sixing, Jun Liu

المصدر: Journal for ImmunoTherapy of Cancer, Vol 9, Iss 6 (2021)
Journal for Immunotherapy of Cancer

مصطلحات موضوعية: lymphocytes, 0301 basic medicine, Cancer Research, Lung Neoplasms, Lymphocyte, medicine.medical_treatment, Programmed Cell Death 1 Receptor, Immunology, chemical and pharmacologic phenomena, CD8-Positive T-Lymphocytes, 03 medical and health sciences, Lymphocytes, Tumor-Infiltrating, 0302 clinical medicine, Immune system, PD-L1, Immunotherapy Biomarkers, Tumor Microenvironment, medicine, Humans, Immunology and Allergy, Lung cancer, RC254-282, Pharmacology, Tumor microenvironment, biology, business.industry, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Immunosuppression, hemic and immune systems, Immunotherapy, tumor-infiltrating, Prognosis, medicine.disease, Tumor Burden, 030104 developmental biology, medicine.anatomical_structure, Oncology, 030220 oncology & carcinogenesis, Mutation, biology.protein, Cancer research, Molecular Medicine, business, Progressive disease

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48237d0b194bf39afc40c41ccf65e28cTest
https://jitc.bmj.com/content/9/6/e002356.fullTest

10

Genomic profiling of advanced cervical cancer to predict response to programmed death-1 inhibitor combination therapy: a secondary analysis of the CLAP trial

المؤلفون: Chunyan Lan, Zhimin Liu, Dongqin Zhu, Fan Yang, Minjun He, Hongyu Peng, Chongjie Tong, Xiao-Long Zhang, Xin Huang, Jiani C. Yin, Junli Zhang, Yang Shao

المصدر: Journal for ImmunoTherapy of Cancer, Vol 9, Iss 5 (2021)
Journal for Immunotherapy of Cancer

مصطلحات موضوعية: 0301 basic medicine, Oncology, Cancer Research, Time Factors, Pyridines, medicine.medical_treatment, Programmed Cell Death 1 Receptor, Phases of clinical research, Uterine Cervical Neoplasms, chemistry.chemical_compound, 0302 clinical medicine, Risk Factors, Immunotherapy Biomarkers, Antineoplastic Combined Chemotherapy Protocols, Immunology and Allergy, Apatinib, Immune Checkpoint Inhibitors, RC254-282, Cervical cancer, biology, medicine.diagnostic_test, High-Throughput Nucleotide Sequencing, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Middle Aged, Progression-Free Survival, drug therapy, Gene Expression Regulation, Neoplastic, 030220 oncology & carcinogenesis, Disease Progression, Molecular Medicine, Female, immunotherapy, Signal Transduction, Adult, medicine.medical_specialty, Combination therapy, Immunology, Antibodies, Monoclonal, Humanized, Risk Assessment, 03 medical and health sciences, Predictive Value of Tests, Internal medicine, Biopsy, medicine, PTEN, Humans, Protein Kinase Inhibitors, PI3K/AKT/mTOR pathway, Aged, combination, Pharmacology, business.industry, Gene Expression Profiling, Immunotherapy, medicine.disease, 030104 developmental biology, chemistry, genetic markers, biology.protein, business, Transcriptome

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f04b4bdd5597fc08e7efbeb45dcf1695Test
https://jitc.bmj.com/content/9/5/e002223.fullTest

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