دورية أكاديمية
Molecular docking for thrombolytic activity of some isolated compounds from Clausena lansium.
| العنوان: | Molecular docking for thrombolytic activity of some isolated compounds from Clausena lansium. |
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| المؤلفون: | Arkajyoti Paul, Mohuya Majumder, Abdul Gafur, Sabrina Qureshi, Joy Chakraborty, Md. Abdullah Al Masum, Md. Nazim Uddin Chy, Mohammad Shah Hafez Kabir |
| المصدر: | Jounal of Negative and No Positive Results, Vol 2, Iss 3, Pp 115-119 (2017) |
| بيانات النشر: | Asociación Para el Progreso de la Biomedicina, 2017. |
| سنة النشر: | 2017 |
| المجموعة: | LCC:Medicine LCC:Science |
| مصطلحات موضوعية: | Clausena lansium, thrombolytic activity, Molecular docking, Clausemarin B, Medicine, Science |
| الوصف: | Clausena lansium (Family- Rutaceae) is commonly known as wampee, is found in fallow lands throughout Bangladesh. Our aim of the study to performed molecular docking studies to identify potential binding affinities of the phytocompounds from Clausena lansium, namely Clausemarin B, Clausenaline C, Clausenaline E, Murrayanine, vanillic acid and Xanthotoxol for searching of lead molecule for thrombolytic activity. A wide range of docking score found during molecular docking by Schrodinger. Clausemarin B , Clausenaline C , Clausenaline E, Murrayanine , vanillic acid and Xanthotoxol showed the docking score -6.926, -4.041, -4.889 , -4.356, -3.007 and -5.816 respectively. Among all the compounds Clausemarin B showed the best docking score. So, Clausemarin B is the best compounds for thrombolytic activity, as it possessed the best value in Molecular docking. Further in vivo investigation need to identify the thrombolytic activity of isolated compounds from Clausena lansium. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English Spanish; Castilian |
| تدمد: | 2529-850X |
| العلاقة: | http://www.jonnpr.com/pdf/1223.pdfTest; https://doaj.org/toc/2529-850XTest |
| DOI: | 10.19230/jonnpr.1223 |
| الوصول الحر: | https://doaj.org/article/1602dac653e14376ae216ecf1a1e3d9cTest |
| رقم الانضمام: | edsdoj.1602dac653e14376ae216ecf1a1e3d9c |
| قاعدة البيانات: | Directory of Open Access Journals |
| تدمد: | 2529850X |
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| DOI: | 10.19230/jonnpr.1223 |