CA19-9 versus CA-125 in Endometriosis
| العنوان: | CA19-9 versus CA-125 in Endometriosis |
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| المؤلفون: | Hind S. Abdulsalam, Hayfaa S. AL-Hadithi, H. Hassan |
| المصدر: | IOSR Journal of Dental and Medical Sciences. 13:27-30 |
| بيانات النشر: | IOSR Journals, 2014. |
| سنة النشر: | 2014 |
| مصطلحات موضوعية: | Infertility, medicine.medical_specialty, Pathology, business.industry, Uterus, Endometriosis, Adhesion (medicine), Inflammation, medicine.disease, Gastroenterology, medicine.anatomical_structure, Internal medicine, medicine, CA19-9, medicine.symptom, Stage (cooking), business, Tumor marker |
| الوصف: | Summary: Background: -Endometriosis is a condition characterized by the presence of endometrial tissue in ectopic foci outside the uterus. The lesions are not cancerous, but they can develop to the point that they cause obstruction or adhesion that attach to nearby organs, causing pain, inflammation, and sometimes infertility. Recently a tumor marker has been used in endometriosis which is CA- 125 (cancer antigen or carbohydrate antigen 125). Objective:-To evaluate the affectivity of serum CA19-9versus serum CA-125in the diagnosis of endometriosis. Patients and methods: -This study applied on 51women with endometriosis compared to 33 healthy women as control group starting from November 2011 to end of January 2012.Their serum samples were collected to investigate serum concentrations of CA-125 and CA19-9 by using ELISA technique. Results: -Serum level of CA-125 and CA19-9 weresignificantly increase inpatientswith endometriosis.Serum CA-125 level was significantly higher in stage III and IV, whileserum CA19-9 levels were only significantly increase in those with stage IV endometriosis. Alsothe highest sensitivity and PPV was for CA-125, while serum CA19-9 test had 5% sensitivity and 95% specificity but with lower accuracy than CA-125. Conclusion: -Serum CA-125 and CA19-9 were significantly higher in endometriosis patients than in control group,and their levels were very useful in predicting the severity of the disease. |
| تدمد: | 2279-0853 2279-0861 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_________::82723c6986bf654cbb0d0eddf42eb021Test https://doi.org/10.9790/0853-13432730Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi...........82723c6986bf654cbb0d0eddf42eb021 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 22790853 22790861 |
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