An unusual case of anti-glomerular basement membrane disease presenting with nephrotic syndrome
| العنوان: | An unusual case of anti-glomerular basement membrane disease presenting with nephrotic syndrome |
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| المؤلفون: | David T. Bourne, Turki O. Alhussain, Rasheed A. Balogun, Chidi C. Okafor, Emaad M. Abdel-Rahman |
| المصدر: | International Urology and Nephrology. 43:1249-1253 |
| بيانات النشر: | Springer Science and Business Media LLC, 2010. |
| سنة النشر: | 2010 |
| مصطلحات موضوعية: | Nephrology, medicine.medical_specialty, Pathology, Nephrotic Syndrome, Anti-Glomerular Basement Membrane Disease, Urology, urologic and male genital diseases, Renal Dialysis, Oliguria, Internal medicine, medicine, Humans, Hematuria, Basement membrane, Proteinuria, urogenital system, business.industry, Acute kidney injury, Middle Aged, medicine.disease, female genital diseases and pregnancy complications, medicine.anatomical_structure, Immunology, Female, Differential diagnosis, medicine.symptom, business, Nephrotic syndrome |
| الوصف: | Anti-glomerular basement membrane (anti-GBM) disease is a vasculitic disease characterized by acute kidney injury, oliguria, hematuria and proteinuria. Proteinuria is rarely in the nephrotic range. A case of anti-GBM disease with proteinuria of 22.5 g/day is discussed. Immunofluorescence showed strong linear IgG deposits while electron microscopy showed widespread visceral epithelial cell foot cell process effacement. No electron dense immune complex-type deposits were identified. Pathology findings were not suggestive of simultaneous presentation of anti-GBM disease and other diseases associated with nephrotic range proteinuria. Anti-GBM disease should be considered in a comprehensive differential diagnosis of severe proteinuria. |
| تدمد: | 1573-2584 0301-1623 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfb17c233e5d38c4193873ed42e5ba0dTest https://doi.org/10.1007/s11255-010-9862-0Test |
| حقوق: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....bfb17c233e5d38c4193873ed42e5ba0d |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15732584 03011623 |
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