AimTo report on the International Collaboration of Orthopaedic Nursing, a mostly virtual network of orthopaedic nursing organizations across four continents. BackgroundFormed by leaders of three national associations, the collaboration is based on recognition of patient problems and challenges shared by orthopaedic nurses globally. Methods/InitiativesThe Collaboration provides a range of services including education, mentoring, and organizational development. Low cost internet-based technologies, such as email and Skype, support global networking in real time. Discussion/Implications for Nursing and Health PolicyThe Collaboration is a cost effective example of how nurses can collaborate internationally to promote the highest standards of orthopaedic nursing.