التفاصيل البيبلوغرافية
| العنوان: |
Impact, Frequency, and Severity of Restless Legs Syndrome in Patients with Multiple Sclerosis in Argentina. |
| المؤلفون: |
Carnero Contentti, Edgar, López, Pablo A., Nadur, Debora, Balbuena, María Eugenia, Finkelstein, Ana Mariel, Tkachuk, Verónica |
| المصدر: |
International Journal of MS Care; Jul/Aug2019, Vol. 21 Issue 4, p157-165, 9p |
| مصطلحات موضوعية: |
MENTAL depression risk factors, SLEEP disorders, ANXIETY risk factors, FATIGUE risk factors, CHI-squared test, CONFIDENCE intervals, FISHER exact test, HYPERSOMNIA, INSOMNIA, INTERVIEWING, MULTIPLE sclerosis, MULTIVARIATE analysis, PSYCHOLOGICAL tests, QUESTIONNAIRES, SELF-evaluation, SMOKING, SPOUSES, T-test (Statistics), RESTLESS legs syndrome, MULTIPLE regression analysis, CROSS-sectional method, SEVERITY of illness index, CASE-control method, DISEASE duration, DATA analysis software, DESCRIPTIVE statistics, ODDS ratio, MANN Whitney U Test, DISEASE risk factors |
| مصطلحات جغرافية: |
ARGENTINA |
| مستخلص: |
Background: Restless legs syndrome (RLS) frequency, and its association with depression, anxiety, sleep disorders, and fatigue, has not been previously studied in Latin American patients with multiple sclerosis (MS). Wfe aimed to assess RLS frequency in patients with MS living in Argentina and to examine potential associations with depression, anxiety, and sleep disorders. Methods: A cross-sectional study (n = 427) was conducted using a self-administered questionnaire, including International RLS Study Group criteria, to compare RLS frequency in patients with MS versus controls. The Hospital Anxiety and Depression Scale and the Fatigue Severity Scale were administered to all participants. Insomnia, excessive daytime somnolence, and other risk factors in patients with MS with RLS were analyzed using logistic regression. Results: Wfe included 189 patients with definite MS and 238 controls. The RLS frequency was 29.1% in patients with MS versus 13.0% in controls (odds ratio [OR] = 2.74, P = .00005). Moreover, clinically significant RLS (csRLS; ie, symptoms present >2 days per week) frequency was 19.4% in patients with MS versus 4.2% in controls (OR = 5.37, P < .00001). Longer MS duration and presence of anxiety, depression, insomnia, and smoking cigarettes were all significantly associated with RLS. Multivariate analysis showed that anxiety and fatigue were significantly associated with MS with RLS and MS with csRLS. Conclusions: Both RLS and csRLS showed strong association with MS, supporting the need to screen for anxiety/depression, sleep quality, and fatigue in this patient population. Wfe believe that identifying the presence and severity of these conditions would contribute to better MS management and treatment. [ABSTRACT FROM AUTHOR] |
|
Copyright of International Journal of MS Care is the property of Consortium of Multiple Sclerosis Centers and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| قاعدة البيانات: |
Complementary Index |
Full Text Finder