التفاصيل البيبلوغرافية
| العنوان: |
A Multidisciplinary Approach to Patients with Psoriasis and a History of Malignancies or On-Treatment for Solid Tumors: A Narrative Literature Review. |
| المؤلفون: |
Denaro, Nerina, Nazzaro, Gianluca, Murgia, Giulia, Scarfì, Federica, Cauchi, Carolina, Carrera, Carlo Giovanni, Cattaneo, Angelo, Solinas, Cinzia, Scartozzi, Mario, Marzano, Angelo Valerio, Garrone, Ornella, Passoni, Emanuela |
| المصدر: |
International Journal of Molecular Sciences; Dec2023, Vol. 24 Issue 24, p17540, 14p |
| مصطلحات موضوعية: |
LITERATURE reviews, PSORIASIS, SYMPTOMS, TUMORS, DISEASE risk factors |
| مستخلص: |
Psoriasis is a chronic immune-mediated disease that is linked to an increased risk of cancer. Although numerous studies have explored whether neoplasms are concurrent conditions or are induced by psoriasis, a definitive definition remains elusive. In this study, we conducted a comprehensive narrative literature review to offer practical guidance to oncologists and dermatologists regarding the initiation and discontinuation of biologics for psoriasis. The findings indicate that a customized approach is recommended for each patient, and that a history of malignancies does not constitute an absolute contraindication for biologics. Growing evidence supports the treatment of selected patients, emphasizing a nuanced assessment of benefits and risks. There is a lack of data specifying a safe timeframe to initiate biologics following a neoplasm diagnosis due to influences from cancer-related and patient-specific characteristics impacting prognosis. Some patients may continue anti-psoriasis therapy during cancer treatments. Enhanced comprehension of the biological mechanisms in cancer progression and the immune microenvironment of psoriasis holds promise for refining therapeutic strategies. In conclusion, a personalized treatment approach necessitates collaboration between oncologists and dermatologists, considering factors such as cancer prognosis, psoriasis clinical manifestations, patient characteristics, and preferences when making treatment decisions. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
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